Results 51 to 60 of about 60,376 (258)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Suicidality among Students: An Experiment of Agnew's General Strain Theory [PDF]

جامعه شناسی کاربردی, 2014
Introduction Agnew's general strain theory is one of the best known theories of criminology. The popularity of this theory is derived from its scope and breadth which allows researchers to investigate about the effects of a variety of structural and ...
Neda Usefi, Akbar Aliverdinia
doaj   +2 more sources

Self-objectification and eating disorder pathology in an ethnically diverse sample of adult women: cross-sectional and short-term longitudinal associations

Journal of Eating Disorders, 2019
Background Extensive support exists for objectification theory’s original aim of explaining patterns of women’s mental health risk through a sociocultural lens.
Lisa Smith Kilpela, Rachel Calogero, Salomé A. Wilfred, Christina L. Verzijl, Willie J. Hale, Carolyn Black Becker   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Survey response rates by requestor’s characteristics

Advancements in Agricultural Development
Response rates are crucial for the effectiveness of survey-based behavioral science and the validity of research conclusions. This study investigates the impact of the characteristics of individuals requesting participation on response rates in online ...
Jason D. McKibben, Christopher A. Clemons, Jessica M. Blythe   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Impact of Economic Capital on Social Tolerance with the Mediation of Social Capital and Cultural Capital among Citizens of Isfahan Province [PDF]

جامعه شناسی کاربردی
Introduction Tolerance is defined as the acceptance and peaceful coexistence with individuals, who differ in values, beliefs, culture, ethnicity, religion, politics, or economics. Social tolerance extends beyond mere endurance; it encompasses respect for
Seyyed Saeed Zabihi Hoseini, Hasan Kheyri, Rza Parizad   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source