Results 41 to 50 of about 1,323,764 (303)

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

open access: yesAdvanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang   +10 more
wiley   +1 more source

Mujeres, música y memoria en San Juan: 1900-1930 Womens, music and memory in San Juan city: 1900-1930

open access: yesLa Aljaba, 2009
Esta miscelánea se refiere a mi libro publicado en 2008 con el título "Mujeres, música y memoria en San Juan. 1900-1930". El mismo trata de la memoria (y la identidad) musical femenina de un San Juan que despertaba al siglo XX incorporándose al mundo ...
Patricia Blanco
doaj  

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

open access: yesAdvanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia   +6 more
wiley   +1 more source

An hydroelectrical dam in the San Juan River? (Informative article) ¿Una represa hidroeléctrica sobre el río San Juan? (Artículo informativo)

open access: yesTecnología en Marcha, 2012
The author uses the geomorphological map of the San Juan River border sector to indicate the conse- quences for the border area with Costa Rica by the waters rising of the San Juan river hydroelectrical project.El autor utiliza el mapa geomorfológico del
Jean Pierre Bergoeing Guida
doaj  

Editor\u27s Note [PDF]

open access: yes, 1995
The articles found in this issue of Explorations in Ethnic Studies focus on a wide variety of topics. The first article by E. San Juan, Jr. challenges Ethnic Studies scholars to reassess the principles and goals of the discipline.
Carranza, Miguel A.
core   +1 more source

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

open access: yesAdvanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra   +23 more
wiley   +1 more source

TGFβ1 Activates Lnc‐APUE to Promote Tumor Metastasis via the Alu Element‐Driven STAU1‐Mediated Decay of CDH1 mRNA

open access: yesAdvanced Science, EarlyView.
We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li   +10 more
wiley   +1 more source

Spring Break In Puerto Rico: Helping Hurricane Victims 3-7-2018 [PDF]

open access: yes, 2018
With FEMA assistance lagging and hundreds of thousands still lacking basic amenities, an intrepid group of RWU Law students heads to San Juan, offering legal assistance to their neediest fellow ...
Bowden, Michael M.
core   +2 more sources

Spontaneous CP Violation [PDF]

open access: yes, 1998
In this talk I begin with some general discussion of the history of CP violation, then move on to aspects of the aspon model including the production of new particles at LHC, implications for B decay, generalized Cabibbo mixing and a reevaluation of kaon
Frampton, Paul H.
core   +3 more sources

Mannose‐Modified Cationic Liposome‐Based mRNA Therapeutics for Improved Triple‐Negative Breast Cancer Immunotherapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
Schematic illustration of mTEM8‐loaded cationic liposome (cLipo‐Man/mTEM8) therapeutics for improved triple‐negative breast cancer immunotherapy. Despite triple‐negative breast cancer (TNBC) is the most heterogeneous and aggressive subtype of breast cancer, immunotherapy is emerging as a promising therapy.
Kexin Deng   +10 more
wiley   +1 more source

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