Results 111 to 120 of about 3,151,138 (201)

Molecular analysis of BRCA1 and BRCA2 genes in La Rioja (Spain): five new variants

open access: yesHereditary Cancer in Clinical Practice
Background To study BRCA1/2 gene variants in La Rioja in the northcentral area of Spain. Methods We performed a molecular analysis of BRCA1 and BRCA2 in 642 individuals from 427 different families from June 2008 to December 2019. Results We identified 71
Raquel Salazar Saez   +10 more
doaj   +1 more source

Tau‐PET correlates of mild behavioral impairment in preclinical and prodromal Alzheimer's disease: A head‐to‐head comparison of Flortaucipir and MK6240

open access: yesAlzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION We compared the association between mild behavioral impairment (MBI) and first‐ versus second‐generation tau‐positron emission tomography (PET) tracers in preclinical and prodromal Alzheimer's disease (AD). METHODS We assessed 110 individuals with head‐to‐head [18F]MK6240 and [18F]Flortaucipir tau‐PET.
Isabella Bizzi   +83 more
wiley   +1 more source

Synergistic Cytotoxicity of Cafestol and Kahweol With Doxorubicin in Breast Cancer Cells Involves TNF‑α Targeting and NF‑κB Downregulation

open access: yesArchiv der Pharmazie, Volume 359, Issue 10, October 2026.
Cafestol and kahweol (C&K) are cytotoxic to breast cancer cells and have a synergistic effect with doxorubicin. C&K interact with TNF‐α and downregulate the TNF‐α/NF‐κB pathway, underscoring their therapeutic potential for breast cancer. NIAID Visual & Medical Arts. Generic Cells. NIAID NIH BIOART Source. bioart.niaid.nih.gov/bioart/171. NIAID Visual &
Layane D. Souza   +16 more
wiley   +1 more source

An ecosystem model of San Pedro Bay, Leyte, Philippines: initial parameter estimates [PDF]

open access: yes
A mass-balance model of the trophic structure of San Pedro Bay, Leyte Province, Philippines was constructed using the Ecopath modeling software. The model is composed of 16 ecological groups (13 consumer, 2 producers, 1 detritus groups).
Campos, W.L.
core  

Cocinemos con mostaza

open access: yes, 2012
En Argentina, investigaciones desarrolladas en el INTA San Pedro han permitido obtener el primer cultivar nacional de mostaza blanca, que se denominó Delfina INTA. Las posibilidades de producción para autoabastecimiento y exportación son muy interesantes,
Pángaro, Federico, Taibo, Juan M.
core   +1 more source

Metformin Attenuates Behavioral Deficits and Oxidative Stress in a Preclinical Model of Autism

open access: yesDevelopmental Neurobiology, Volume 86, Issue 4, October 2026.
ABSTRACT Autism spectrum disorder (ASD) is a complex neurodevelopmental condition lacking effective pharmacological treatments. Metformin has emerged as a candidate for drug repurposing in ASD due to its metabolic and neurobiological actions. This study evaluated the in vivo effects of metformin (400 mg/kg, orally) administered from postnatal day 21 to
Madna Costa Freitas   +9 more
wiley   +1 more source

(+)‐Trans‐Cannabidiol Is an Agonist at Human CB2 Receptors

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT (−)‐trans‐Cannabidiol ((−)‐CBD) is a principal phytocannabinoid from Cannabis sativa. (−)‐CBD has complex pharmacology but is a relatively weak inhibitor of CB1 and CB2 receptor signaling. Cannabidiol has two chiral centres and thus four stereoisomers.
Pedro Bans Burtchaell   +6 more
wiley   +1 more source

Pisos de vegetación de la Sierra de San Pedro Mártir, Baja California, México

open access: yesActa Botanica Mexicana, 1994
Se describen los pisos de vegetación de la sierra de San Pedro Mártir, Baja California. El estudio se ha realizado mediante fotointerpretación de unidades de vegetación, las cuales se identificaron en el campo como asociaciones empleando técnicas ...
Manuel Peinado   +3 more
doaj  

Polyglycolic Acid Polymer Versus Porcine Small Intestine Submucosa Graft After Plaque Incision in Peyronie's Disease: A Comparative Study

open access: yesAndrology, Volume 14, Issue 7, Page 2160-2165, October 2026.
ABSTRACT Background Peyronie's disease (PD) with severe penile curvature often requires surgical correction through plaque incision and grafting (PIG). Objectives To compare surgical outcomes between polyglycolic acid polymer grafts and porcine small intestinal submucosa (SIS) grafts in patients undergoing PIG for PD.
Renan Trevisan Jost   +7 more
wiley   +1 more source

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