Results 281 to 290 of about 5,908,011 (360)

Implementation of guideline‐recommended medical therapy for patients with heart failure in Europe

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 790-798, April 2025.
Abstract Physicians' adherence to guideline‐recommended heart failure (HF) treatment remains suboptimal, especially regarding the target doses. In particular, there is evidence that non‐cardiologists are less compliant with HF guideline recommendations. This is likely to have a detrimental impact on patients' survival, readmissions and quality of life.
Maurizio Volterrani   +11 more
wiley   +1 more source

‘Free to Be Me?’: Gender Role Norms Constrain Career Interests Less for Lesbian, Gay and Bisexual People Than for Heterosexual People

open access: yesEuropean Journal of Social Psychology, EarlyView.
ABSTRACT Societal gender role norms play a crucial role in shaping men's and women's career aspirations. However, prior research documenting this key role of gendered norms has primarily focused on heterosexual women and men in the global North‐West. Previous studies documenting differences in career interests by sexual orientation suggest that gender ...
Katharina Block   +136 more
wiley   +1 more source

Frailty and All-Cause Mortality Among People With HIV Engaged in Clinical Care in the United States. [PDF]

open access: yesJ Acquir Immune Defic Syndr
Ruderman SA   +14 more
europepmc   +1 more source

Digital Rights Activism in Multilevel Governance

open access: yesEuropean Policy Analysis, EarlyView.
ABSTRACT Multilevel governance (MLG) without a clear hierarchical structure can create power imbalances among various actors, particularly in settings with overlapping jurisdictions and policy areas. This dynamic is especially pronounced in Internet governance, which faces a complex interplay of domestic laws, state interdependence, and heightened ...
Alison Harcourt
wiley   +1 more source

Cure Sickle Cell Initiative recommendations on common data elements for sickle cell disease gene therapy trials. [PDF]

open access: yesBlood Adv
Lanzkron S   +11 more
europepmc   +1 more source

Evolution of the European Medicines Agency clinical guidelines for epilepsy drug development between 2010 and 2025: A comparative analysis by the ILAE Task Force on Regulatory Affairs

open access: yesEpilepsia, EarlyView.
Abstract Objective The latest European Medicines Agency (EMA) guideline on the clinical investigation of medicines to treat epileptic disorders was adopted by the EMA Committee for Medicinal Products for Human Use in 2025. We compared this guideline with the previous version (2010), highlighting areas where significant revisions were introduced ...
Stéphane Auvin   +7 more
wiley   +1 more source

Intracranial electroencephalographic connectivity analysis to localize epileptogenic networks: Systematic review and meta‐analysis from ILAE Epilepsy Surgery Networks Task Force

open access: yesEpilepsia, EarlyView.
Abstract Intracranial electroencephalographic (iEEG) connectivity analysis is a promising method to localize epileptic networks and guide surgical planning in focal drug‐resistant epilepsy. Despite numerous studies exploring its utility, the added value of iEEG connectivity over standard clinical presurgical evaluation remains unclear.
Nishant Sinha   +15 more
wiley   +1 more source

Systematic statistical analysis of change in SEIzure interVAL with diazepam nasal spray supports this novel clinical endpoint for immediate‐use seizure medication

open access: yesEpilepsia, EarlyView.
Abstract Objective Appropriate endpoints for daily antiseizure medications may differ from those for intermittent, immediate‐use seizure medications (ISMs). The observed interval between seizure clusters over time (SEIzure interVAL [SEIVAL]) has been proposed as a novel effectiveness endpoint for ISMs.
Wesley T. Kerr   +4 more
wiley   +1 more source

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