Results 171 to 180 of about 166,876 (291)

Procedure for executing administrative sanctions

, 2019
The purpose of this investigation is to analyze the justification of the existence of means and procedure of forced execution of the administrative sanctions before the voluntary breach of the provisions in the sanctioning administrative act by the offender.
openaire   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Impact of volcanic eruptions on heavy metal contamination in the food chain. [PDF]

Ital J Food Saf
Pulze S, Presti N, Anastasio A.
europepmc   +1 more source

A concept for multi-winner tenders for medicinal products with balancing between efficient prices, long-term competition and sustainability of supply. [PDF]

Front Med (Lausanne), 2023
Németh G, Mágó ML, Kaló Z, Lám J, Balogh T, Brodszky V.   +5 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Examining the presence and effects of coherence and fragmentation in the Gulf of Maine fishery management network. [PDF]

Reg Environ Change
Katznelson D, Sohns A, Kim D, Roozee E, Donner WR, Song AM, de Vries JR, Temby O, Hickey GM.   +8 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Statistic tells: the regulatory pendulum of permit trajectories in China's genetic governance (2021-2024). [PDF]

Front Genet
Song L, Liu Z, Meng F.
europepmc   +1 more source

Treble Damages, Deterrence, and Their Relation to Substantive Law: Ramifications Under the Insider Trading Sanctions Act of 1984 [PDF]

, 2011
Metzger, Michael J.
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source