Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron
Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej +20 more
wiley +2 more sources
Investigation of Solar Waste Sand as a Supplementary Raw Material for Ordinary Portland Cement Clinker Production. [PDF]
Smith RE +3 more
europepmc +1 more source
ABSTRACT The 2023 Australian Voice to Parliament Referendum presented a pivotal moment in the nation's democratic landscape. Despite support for Indigenous well‐being, the referendum did not secure the necessary approval, prompting extensive analysis of its outcome.
Scott Baum, William Mitchell
wiley +1 more source
Direct synthesis of sulfonimide‐based polymers of intrinsic microporosity enables comparison with compositionally similar flexible analogs. Incorporation of a common pore‐filling transport medium drives these fundamentally different polymer architectures toward similar bulk conductivity and mechanical properties while revealing distinct microscopic ion‐
Abraham Herzog‐Arbeitman +8 more
wiley +2 more sources
Research on the Mechanism of High-Performance Aluminum Alloy Casting of Frozen Sand Mold Coupled with Negative Pressure. [PDF]
Luo L +9 more
europepmc +1 more source
ABSTRACT Education is a central mechanism for ensuring that Indigenous–State treaties are understood, supported and endure through political change. Public knowledge shapes the negotiation, acceptance, implementation and long‐term stability of agreements. In Australia, however, treaty knowledge remains fragmented.
Jacob Prehn, Harry Hobbs, Jessica Horton
wiley +1 more source
Quantifying the Sites of Government, Commercial, and Personal Systems‐Perpetrated Financial Abuse
ABSTRACT This study explores the institutional systems through which post‐separation financial abuse is perpetrated. While existing measures seek to quantify the harms experienced by women post‐separation, this study draws on financial, welfare and legal service casefiles to identify where such harms occur. Drawing on 76 de‐identified Victorian service
Kay Cook +3 more
wiley +1 more source
T Cell‐Mediated Targeting of Interneurons in Mice Shapes Hippocampal Remodeling and Epilepsy
Objective Autoimmune encephalitis (AE) is associated with autoantibodies targeting distinct neuronal populations. In AE, antibodies against glutamate decarboxylase 65 (GAD65), expressed in GABAergic interneurons, are frequently detected. In GAD65‐AE, hippocampal biopsies often show infiltrates of CD8+ cytotoxic T cells (CTLs), suggesting a prominent T ...
Daniel S. Galvis‐Montes +6 more
wiley +1 more source
Numerical simulation of productivity evaluation for multi-cluster fracturing in horizontal wells considering non-uniform proppant placement within fractures. [PDF]
Wang Y +8 more
europepmc +1 more source
Study on the pollution law of complex working conditions in sand-filled fracture well washing operation. [PDF]
Shi W +6 more
europepmc +1 more source

