Results 41 to 50 of about 13,229 (184)

VALIDAÇÃO DE PROCESSO PRODUTIVO AUTOMATIZADO DE POOL DE PLAQUETAS RANDÔMICAS LEUCORREDUZIDO PARA ATINGIR CONTAGEM PLAQUETÁRIA EQUIVALENTE AOS CONCENTRADOS DE TROMBOCITAFÉRESE

Hematology, Transfusion and Cell Therapy
Objetivo: Validar a produção de pool de plaquetas randômicas leucorreduzido, padronizando o método para atingir rendimentos plaquetários iguais ou superiores os dos concentrados de plaquetas por aférese, garantindo a qualidade do produto, conforme ...
AJ Araujo, VGM Costa, WM Silva, AAA Castro, AFA Campos, ECP Assis, RF Cardoso, LHR Gabriel   +7 more
doaj   +1 more source

IMPLEMENTAÇÃO DO PROGRAMA DE LAVAGEM DE MÃOS NO SERVIÇO DE HEMOTERAPIA PARA MELHORIA DA SEGURANÇA DO PACIENTE/DOADOR/COLABORADOR

Hematology, Transfusion and Cell Therapy, 2023
Objetivo: Promover a adesão dos colaboradores ao processo de lavagem de mãos, a partir da realização de uma dinâmica estabelecida, visando a melhoria na segurança do ciclo do sangue.
NMO Godinho, TS Oliveira, F Latini, A Cortez, KCM Souza   +4 more
doaj   +1 more source

Functional validation of a modified platelet desialylation test for immune and hereditary thrombocytopenias

Transfusion Medicine, EarlyView.
Abstract Background Thrombocytopenia arises from heterogeneous inherited and acquired disorders, and identifying the underlying platelet clearance mechanisms remains challenging. Platelet desialylation, characterised by loss of sialic acid and consequent exposure of terminal β‐galactose residues recognised by the Ashwell–Morell receptor, represents an ...
Karen Nogueira Chinoca Ziza, Thamy Caroline Silva, Mateus Domentino, Marina Cavalcanti Albuquerque Veiga Conrado, João Vitor Bernardo Oliveira, Felipe Augusto Rós, Caroline Gabe, Elyse Moritz, Akemi Chiba, Paula Villaça, Vanderson Rocha, Alfredo Mendrone‐Junior, José Bordin, Dante Langhi, Carla Luana Dinardo   +14 more
wiley   +1 more source

Platelet aggregation and lipoprotein levels in a patient with familial hypercholescholesterolemia after selective LDL-apheresis

São Paulo Medical Journal
Platelet aggregation was studied in a patient with familial hypercholesterolemia immediately after aphereis selective for low-density lipoprotein (LDL), a lipid-lowering procedure.This treatment reduced plasmatic levels of total and LDL-cholesterol, apo ...
Madalena Nunes da Silva Pares, Elbio Antonio D'Amico, José Mauro Kutner, Dalton de Alencar Fischer Chamone, Sergio Paulo Bydlowski   +4 more
doaj   +1 more source

HTLV screening and confirmatory testing among blood donors in São Paulo: A cross‐sectional study

Transfusion Medicine, EarlyView.
Abstract Introduction Human T‐cell lymphotropic virus types 1 and 2 (HTLV‐1/2) are transfusion‐transmissible retroviruses associated with severe diseases, and blood donor screening is mandatory in Brazil. Increasing HTLV‐related discard rates at our institution prompted this study to determine the prevalence and incidence of HTLV‐1/2 and to investigate
Suzete C. Ferreira, Anna S. Nishyia, Jerenice E. Ferreira, Claudia Di Lorenzo Oliveira, Cesar de Almeida‐Neto, Tila Fanciani, Katia C. Dantas, Juliana Derriga, Silvia Petrossi Gallo Polato, Nanci Salles, Vanderson Rocha, Alfredo Mendrone‐Junior   +11 more
wiley   +1 more source

Signal to cut-off (S/CO) ratio and detection of HCV genotype 1 by real-time PCR one-step method: is there any direct relationship?

Brazilian Journal of Infectious Diseases
BACKGROUND: Polymerase chain reaction (PCR) methods play an essential role in providing data related to diagnosis, monitoring and treatment of hepatitis C virus (HCV) infection.
Guilherme Albertoni, CP Arnoni, PRB Araújo, FO Carvalho, JA Barreto   +4 more
doaj   +1 more source

IDENTIFICAÇÃO DE ANTI-G EM GESTANTE: RELATO DE CASO

Hematology, Transfusion and Cell Therapy, 2023
Introdução: O sistema Rh é um dos sistemas mais complexos, sendo o segundo sistema de importância clínica depois do sistema ABO. É composto por mais de 50 antígenos, tendo como principais: D,C,c,E,e.
GF Devides, FS Silva, F Latini, AJP Cortez, CP Arnoni, TAP Vendrame   +5 more
doaj   +1 more source

Clinical application of a modified platelet desialylation test for mechanistic characterization of platelet transfusion refractoriness

Transfusion, EarlyView.
Abstract Background Platelet transfusion refractoriness (PTR) is a major challenge in transfusion medicine and may result from both immune and non‐immune mechanisms. Although alloantibodies are well‐established contributors, Fc‐independent pathways such as platelet desialylation have emerged as alternative mechanisms of clearance.
Karen Ziza, Thamy Silva, Mateus Domentino, Marina Conrado, João Oliveira, Elyse Moritz, Akemi Chiba, Vanderson Rocha, Alfredo Mendrone‐Junior, José Bordin, Langhi Dante, Carla Dinardo   +11 more
wiley   +1 more source

Protection of fundamental human rights by improving patient access to plasma‐derived therapies and donor health protection

Vox Sanguinis, EarlyView.
Abstract Background and Objectives The main use of plasma has evolved into market‐driven plasma‐derived medicinal products (PDMPs), but it still requires donors. Availability of PDMPs in access to care is often considered restrictively, in terms of volumes of plasma required for production and whether or not to remunerate donors.
Jean‐Baptiste Thibert, Leni von Bonsdorff, Jean‐Philippe Plançon, Vincenzo de Angelis, Cynthia So‐Osman, Christian Erikstrup, Pierre Tiberghien, Katja van den Hurk   +7 more
wiley   +1 more source

Molecular characterization of D variants in Brazilian blood donors and their association with RhCE and Duffy phenotypes

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Serological classification of RhD‐negative and weak D is often insufficient in admixed populations, where diverse RHD variants have clinical implications. In Brazil's highly admixed population, RhD interpretation and donor–recipient matching are particularly challenging.
Thamy C. S. Silva, Marcia R. Dezan, Sidneia Costa, Beatriz C. Girardo, Bruno R. Cruz, Karen Ziza, Dante M. Langhi, José O. Bordin, Lilian Castilho, Carla L. Dinardo   +9 more
wiley   +1 more source