Results 71 to 80 of about 367 (228)

Against the Medicalization of Humanity: A Critical Ethnography of a Community Trying to Build a World Free of Sanism and Psychiatric Oppression

, 2012
We have to stop inventing disorders for every human experience that challenges the status quo… I dream of a world where people can peacefully co-exist… [where] differences are accepted… [and where] I, and everybody else, has a place (Jackie, psychiatric ...
Diamond, Shaindl Lin
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

'Things Have Changed': Looking at Non-Institutional Mental Disability Law Through the Sanism Filter

SSRN Electronic Journal, 2002
Almost all the literature about the influence of sanism and pretextuality on the development of mental disability law has dealt with questions of institutionalization and the rights of persons who are subject to commitment to in-patient psychiatric hospitals. Problems of mental disability, however, are not solely institutional problems.
openaire   +2 more sources

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Infinity Goes on Trial: Sanism, Pretextuality, and the Representation of Defendants with Mental Disabilities

, 2016
This paper, presented to the mid-winter meeting of the National Association of Criminal Defense Lawyers (Austin, TX, 2/18/16), explains why it is essential for lawyers representing criminal defendants with mental disabilities to understand the meanings ...
Perlin, Michael L.
core  

A Desire to be ‘Normal’? A Discursive and Intersectional Analysis of ‘Penetration Disorder’

, 2016
Psychiatry’s problematic framing of femininity, women’s bodies, and sexuality has attracted much condemnation (Caplan & Cosgrove, 2004; Frith, 2013; Ussher, 2011).
Carson, Krista, Tosh, Jemma
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Community-Based Accountability Processes Responding to Sexual and Domestic Violence, and the Mental Health Strategies that Sustain Them

, 2022
Community Accountability (CA) processes are one community-based approach to responding to sexual and domestic violence without relying on the state.
Fernandez, Annaliese
core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source