Results 81 to 90 of about 586,723 (251)
How health systems in sub-Saharan Africa can benefit from tuberculosis and other infectious disease programmes. [PDF]
Weak and dysfunctional health systems in low-income countries, particularly in sub-Saharan Africa, are recognised as major obstacles to attaining the health-related Millennium Development Goals by 2015.
Enarson, D A +4 more
core +1 more source
Researchers identified a pancreatic cancer subset with low global protein synthesis but heightened translation of stress‐response genes like ATF4, rendering cells resistant to chemotherapy and apoptosis. These tumors depend on serine and cysteine from surrounding cancer‐associated fibroblasts (CAFs), which shift to produce serine by curbing collagen ...
Sauyeun Shin +25 more
wiley +1 more source
Les Organisations de la Société Civile et la Lutte Contre la Pauvreté en Afrique Subsaharienne [PDF]
The paper presents the role played by civil society organisations to bring down the ...
Aurélien C. Atidegla +11 more
core
Improving the external validity of clinical trials: the case of multiple chronic conditions [PDF]
The U.S. Department of Health and Human Services vision and strategic framework on multiple chronic conditions (MCCs) incorporates recommendations designed to facilitate research that will improve our knowledge about interventions and systems that will ...
Fortin, Martin, Smith, Susan M.
core +4 more sources
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
Extended Fused Carbazole‐BODIPY, High Brightness NIR Organic Dyes
Highly fused boron‐dipyrromethene (BODIPY) with a strong donor group has been synthesized, and their photophysical behaviors fully characterized. They exhibit outstanding brightness for fluorophores emitting in the NIR region. Water‐soluble nanoparticles filled with one of these dyes demonstrate high efficiency as the NIR II visualization agent ...
Fabien Ceugniet +9 more
wiley +2 more sources
Heterogeneity in the Relationship between Disinfection By-Products in Drinking Water and Cancer: A Systematic Review. [PDF]
The epidemiological evidence demonstrating the effect of disinfection by-products (DBPs) from drinking water on colon and rectal cancers is well documented.
Benmarhnia, Tarik +4 more
core +2 more sources
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen +15 more
wiley +1 more source
Objectif : Dans ce papier, nous avons analysé l’effet de la transformation structurelle sur la santé des populations dans les pays de l’Afrique subsaharienne.
Yaovi Fagda Tchota Agbe +1 more
doaj +1 more source
O refúgio e o acesso as políticas públicas de saúde no Brasil
Este artigo apresenta o resultado de um estudo que se insere no Programa de Iniciação Científica, do ciclo de 2017-2018 da Universidade Católica Dom Bosco – UCDB, Campo Grande, Mato Grosso do Sul, Brasil, cujo objetivo é investigar a questão do acesso à ...
Karine Giuliano Soares +1 more
doaj +1 more source

