Results 21 to 30 of about 292,213 (250)
Systematic Assessment of Carbon Emissions from Renewable Energy Access to Improve Rural Livelihoods
One way of increasing access to electricity for impoverished unconnected areas without adding significant amounts of CO2 to the atmosphere is by promoting renewable energy technologies.
Judith A. Cherni +4 more
doaj +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Introducción: Muchas organizaciones tratan de certificar su calidad atendiendo a los requisitos de ISO 9001, 2015. Para lograrlo, deben determinar, proporcionar y mantener la infraestructura necesaria, como se plantea en 7.1.3: “Infraestructura” de dicha
Rogej Arturo Marrero-Hernández +2 more
doaj
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Zoning of coastal erosion in Santa Clara del Mar, Buenos Aires province [PDF]
La zona de estudio comprende el área costera de la localidad de Santa Clara del Mar, ubicada en el sector sudeste de la provincia de Buenos Aires, en el partido de Mar Chiquita.
Bunicontro, Maria Paula +2 more
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
La extensión universitaria como forma de implementarla investigación-acción participativa [PDF]
En la Universidad Nacional de Mar del Plata se está desarrollando una experiencia de articulación entre investigación y extensión, con la finalidad de concretar el proceso de Investigación-Acción Participativa.
Benseny, Graciela +6 more
core
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source

