Results 141 to 150 of about 48,995 (266)

USP7 Regulates TRPV1 Deubiquitination to Mediate Chondrocyte Ferroptosis and Alleviate Osteoarthritis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a common degenerative joint disease characterized by chondrocyte dysfunction. In this study, we explored the function and mechanism of ubiquitin‐specific protease 7 (USP7) in chondrocyte ferroptosis in OA. The USP7, TRPV1, collagen II, and GPX4 levels in knee joint tissue were detected using immunohistochemistry ...
Jun Li, Ding Chen, Wei‐Ye Zhong
wiley   +1 more source

Covalently Immobilized Lignin–Xanthene Conjugates for Persistent Surface Photochemistry and Self‐Sterilizing Interfaces Under Ambient Visible Light

open access: yesMacromolecular Rapid Communications, EarlyView.
Bio‐derived lignin–Eosin Y macromolecular networks are developed as visible‐light‐responsive self‐sterilizing coatings that generate reactive oxygen species without leaching. The spray‐coated photopolymerized surfaces exhibit durable antibacterial and antiviral activity under ambient light for extended periods, demonstrating a scalable and sustainable ...
Euna Oh   +7 more
wiley   +1 more source

LKB1 Loss Sensitizes Lung Tumor Spheres to Mitomet‐Induced Ferroptosis, and These Effects are Enhanced by mTOR Inhibition

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Owing to their robust antioxidant defense mechanisms, cancer stem‐like cells (CSCs) maintain a low level of oxidative stress, which is crucial for preserving stemness and pluripotency. Therefore, agents that either directly generate reactive oxygen species (ROS) or inhibit the antioxidant defense systems can selectively induce oxidative cell ...
Xueqing Liang   +4 more
wiley   +1 more source

Vegetales silvestres sub explotados del Chaco argentino y su potencial como recurso alimenticio

open access: yesArchivos Latinoamericanos de Nutrición
Se ha investigado el valor nutricional de especies vegetales subexplotadas salvajes recolectadas en el Chaco Argentino. Hojas de Hipochaeris sp.-, Coronopus didimus and Portulaca olearacea; frutos de Zyziphus sativa, Brumelia obtusifolia y Eugenia ...
Marcelino R. Freyre   +4 more
doaj  

Next‐Generation Paleopathology: Using Commercial AI in Bioarchaeological Diagnosis

open access: yesInternational Journal of Osteoarchaeology, EarlyView.
ABSTRACT Artificial intelligence encompasses computational systems capable of performing cognitive functions such as learning, reasoning, and problem‐solving. Within this domain, generative AI and large language models such as ChatGPT, Gemini, and Copilot have shown significant potential in clinical diagnostics.
Jessica Mongillo   +4 more
wiley   +1 more source

Genetic analysis of primary lung interdigitating dendritic cell sarcomas

open access: yesThe Journal of Pathology, EarlyView.
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov   +6 more
wiley   +1 more source

Hybrid Metal‐Coated Carbon Fiber/Multi‐Walled Carbon Nanotube Networks for Enhanced Electrical and Mechanical Performance

open access: yesPolymer Composites, EarlyView.
Multifunctional enhancement of metal‐coated carbon fiber/multi‐walled carbon nanotube hybrid composites fabricated by injection molding. ABSTRACT As electronic devices and components continue to become more powerful and highly integrated, there is an increasing demand for lightweight, cost‐effective, and easy‐to‐process conductive materials.
Min Su Kim   +6 more
wiley   +1 more source

Open letter: The need for a site‐based biodiversity standard measuring and certifying impacts from nature‐based projects

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Despite growing investment in restoration, weak accountability and poor biodiversity monitoring mean many projects fail to achieve ecological recovery. The Global Biodiversity Standard (TGBS) offers a practical way to ensure that restoration finance delivers measurable gains for nature.
David Bartholomew   +254 more
wiley   +1 more source

Introducing Simple Detection of Bioavailable Arsenic at Rafaela (Santa Fe Province, Argentina) Using the ARSOlux Biosensor. [PDF]

open access: yesInt J Environ Res Public Health, 2015
Siegfried K   +11 more
europepmc   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

open access: yesPest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King   +6 more
wiley   +1 more source

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