Results 21 to 30 of about 48,995 (266)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Aneurismas de las arterias pulmonares en relación al síndrome de Hughes Stovin

Revista Argentina de Reumatología, 2022
El síndrome de Hughes Stovin es una vasculitis de pequeños y grandes vasos, más frecuente en hombres jóvenes. Se manifiesta con trombosis y aneurismas. Inicia con tromboflebitis que evoluciona a aneurismas con eventual desenlace fatal por ruptura de los
Brian Marcelo Abdala, Antonella Baroni, Ana Castelli, Julia Crema, Fernanda Beduino, Ignacio Jesús Masello, Romina Resta   +6 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Phalangeal fractures treated with osteosynthesis plates. Short - term results.

Revista de la Asociación Argentina de Ortopedia y Traumatología, 2018
Introduction A prospective cohort study was carried out to evaluate functional results in workers with phalangeal fractures treated with plates and to establish poor prognostic factors.
Ricardo Martín Gardenal, Matías Santiago Seri, Sebastián José Faccendini, Gastón Bernardo Kalejman, Jorge Ariel Bichara   +4 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Correction: Kolchinsky, A. and Tracey, B.D. Estimating Mixture Entropy with Pairwise Distances. Entropy 2017, 19, 361

Entropy, 2017
Following the publication of our paper [1], we uncovered a mistake in the derivation of two formulas in the manuscript.[...]
Artemy Kolchinsky, Brendan D. Tracey
doaj   +1 more source

Insuficiencia suprarrenal aguda secundaria a hemorragia adrenal espontánea por síndrome antifosfolipídico: serie de casos

Revista Argentina de Reumatología, 2023
En la insuficiencia suprarrenal (ISR) la destrucción progresiva del tejido adrenal conduce a la disminución de la secreción de corticoides suprarrenales de forma tal que, una vez instalada, el cuadro clínico reviste gravedad y, sin tratamiento, una ...
Nadia Benzaquén, Julia Riera, Sebastián Giménez, Maximiliano Castro   +3 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Respuesta a cetuximab en carcinoma escamocelular de canal anal después de varias líneas de quimioterapia e inmunoterapia

Revista Colombiana de Gastroenterología
El cáncer anal primario representa del 1% al 3% de los cánceres gastrointestinales. La histología más común es el carcinoma escamocelular, con una incidencia de 0,5 a 2 por cada 100.000 personas.
Javier Mauricio Segovia, Sergio Alejandro Osorio Sánchez, Erick Andrés Cantor, Luis Eduardo Pino, Henry Alexander Vargas, John Alejandro Murillo Silva, Iván Camilo Triana, Valentina Navas Cardona   +7 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source