Results 11 to 20 of about 75,071 (182)

Two-way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3. [PDF]

FEBS Open Bio
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Ueno R, Terasaki A, Imai Y, Kimura Y, Kojima Y, Irie M, Odaira K, Noura M, Okamoto S, Yasuda T, Tsuzuki S, Kiyoi H, Hayakawa F.   +12 more
europepmc   +2 more sources

Characterization of the complete chloroplast genome of Rhodiola sachalinensis and comparative analysis with its congeneric plants. [PDF]

FEBS Open Bio
The chloroplast genome of Rhodiola sachalinensis was sequenced, assembled, annotated and compared with 24 other Rhodiola species. It had a length of 151 595 bp and a CG content of 37.7%. Within the Rhodiola genus, R. sachalinensis is most closely related to Rhodiola rosea, despite R.
Sun T, Tang Y, Zhou L, Qiao X, Ma X, Qin H, Han Y, Sui C.   +7 more
europepmc   +2 more sources

The linguistic characterisation of Galdós’s characters in his last play, Santa Juana de Castilla

Orbis Litterarum, Volume 78, Issue 1, Page 45-58, February 2023., 2023
Abstract In this work I propose to examine the linguistic characterisation of the characters in Galdós’s last play, Santa Juana de Castilla (Saint Joanna of Castile, 1918). The analysis will show that in addition to the use of archaic language, the purpose of which may be to evoke the era, the linguistic style of the play is characterised by the use of
Miguel Á. Perdomo‐Batista
wiley   +1 more source

DNA release from plant tissue using focused ultrasound extraction (FUSE)

Applications in Plant Sciences, Volume 11, Issue 1, January-February 2023., 2023
Abstract Premise Sample preparation in genomics is a critical step that is often overlooked in molecular workflows and impacts the success of downstream genetic applications. This study explores the use of a recently developed focused ultrasound extraction (FUSE) technique to enable the rapid release of DNA from plant tissues for genetic analysis ...
Alexia Stettinius, Hal Holmes, Qian Zhang, Isabelle Mehochko, Misa Winters, Ruby Hutchison, Adam Maxwell, Jason Holliday, Eli Vlaisavljevich   +8 more
wiley   +1 more source

EORTC‐QLQ‐C30 and SKINDEX‐29 measurement of health‐related quality of life in patients with mycosis fungoides and Sézary syndrome: Real‐world data in Spanish patients (MICADOS Study)

JEADV Clinical Practice, Volume 1, Issue 4, Page 438-449, December 2022., 2022
Abstract Background Few studies have explored the impact of cutaneous T‐cell lymphoma (CTCL) on health‐related quality of life (HRQoL) and compared it to other patients with cancer. Objectives The primary objective of the study was to assess the QoL of patients diagnosed with the mycosis fungoides (MF) and Sézary syndrome (SS) types of CTCL in Spain ...
Belén Navarro Matilla, Mª del Mar Onteniente Gomis, Ramon M. Pujol Vallverdú, Andrea Combalia Escudero, Irma Zapata Paz, Cristina Muniesa Montserrat, Eva González Barca, Mercedes Morillo Andújar, Amparo Pérez Ferriols, Mª Concepción Román Curto, Ricardo Fernández de Misa Cabrera, Mercedes Hospital Gil, Ana Marín Niebla, Pablo J. Rios Rull, Fátima de la Cruz Vicente, Rosa M. Izu Belloso, Alejandro Martín García‐Sancho, M. Elisabet Parera Amer, Raúl Córdoba Mascuñano, María Dolores Ramón Quiles, Ana Saus Carreres, Raquel del Campo García, Salma Machan, Pablo Viguera Ester, Julia Blanco Garnelo, Begoña Soler López, Pablo L. Ortiz Romero   +26 more
wiley   +1 more source

Phosphorylation of hTERT at threonine 249 is a novel tumor biomarker of aggressive cancer with poor prognosis in multiple organs

The Journal of Pathology, Volume 257, Issue 2, Page 172-185, June 2022., 2022
Abstract Recent evidence indicates that RNA‐dependent RNA polymerase (RdRP) activity of human telomerase reverse transcriptase (hTERT) regulates expression of target genes and is directly involved in tumor formation in a telomere‐independent manner. Non‐canonical function of hTERT has been considered as a therapeutic target for cancer therapy.
Yoko Matsuda, Taro Yamashita, Juanjuan Ye, Mami Yasukawa, Keiko Yamakawa, Yuri Mukai, Mitsuhiro Machitani, Yataro Daigo, Yohei Miyagi, Tomoyuki Yokose, Takashi Oshima, Hiroyuki Ito, Soichiro Morinaga, Takeshi Kishida, Toshinari Minamoto, Shinji Yamada, Junko Takei, Mika K Kaneko, Motohiro Kojima, Shuichi Kaneko, Tsutomu Masaki, Masahiro Hirata, Reiji Haba, Keiichi Kontani, Nobuhiro Kanaji, Nobuyuki Miyatake, Keiichi Okano, Yukinari Kato, Kenkichi Masutomi   +28 more
wiley   +1 more source

A sugarcane smut fungus effector simulates the host endogenous elicitor peptide to suppress plant immunity

New Phytologist, Volume 233, Issue 2, Page 919-933, January 2022., 2022
Summary The smut fungus Sporisorium scitamineum causes the most prevalent disease on sugarcane. The mechanism of its pathogenesis, especially the functions and host targets of its effector proteins, are unknown. In order to identify putative effectors involving in S.
Hui Ling, Xueqin Fu, Ning Huang, Zaofa Zhong, Weihua Su, Wenxiong Lin, Haitao Cui, Youxiong Que   +7 more
wiley   +1 more source

Aberrant expression of MYD88 via RNA‐controlling CNOT4 and EXOSC3 in colonic mucosa impacts generation of colonic cancer

Cancer Science, Volume 112, Issue 12, Page 5100-5113, December 2021., 2021
RNA‐controlling CNOT4 was significantly expressed in normal mucosae adjacent to colon cancers. IHC for CNOT4 was performed in 17 CCs and 15 NCCs, and representative images in paracancerous normal colonic mucosae, the paired tumor lesions in CCs, and normal mucosae in NCCs were displayed.
Masumi Tsuda, Misa Noguchi, Tsuyoshi Kurai, Yuji Ichihashi, Koki Ise, Lei Wang, Yusuke Ishida, Mishie Tanino, Satoshi Hirano, Masahiro Asaka, Shinya Tanaka   +10 more
wiley   +1 more source

The Euscaphis japonica genome and the evolution of malvids

The Plant Journal, Volume 108, Issue 5, Page 1382-1399, December 2021., 2021
SUMMARY Malvids is one of the largest clades of rosids, includes 58 families and exhibits remarkable morphological and ecological diversity. Here, we report a high‐quality chromosome‐level genome assembly for Euscaphis japonica, an early‐diverging species within malvids.
Wei‐Hong Sun, Zhen Li, Shuang Xiang, Lin Ni, Diyang Zhang, De‐Qiang Chen, Meng‐Yuan Qiu, Qi‐Gong Zhang, Lin Xiao, Le Din, Yifan Li, Xing‐Yu Liao, Xue‐Die Liu, Yu‐Ting Jiang, Pei‐Lan Zhang, Hui Ni, Yifan Wang, Yi‐Xun Yue, Xi Wu, Xiang‐Qing Din, Wei Huang, Zhi‐Wen Wang, Xiaokai Ma, Bobin Liu, Xiao‐Xing Zou, Yves Van de Peer, Zhong‐Jian Liu, Shuang‐Quan Zou   +27 more
wiley   +1 more source

An Edition of Ambrosio Nieto’s Paradise Lost: A Drama in Four Acts (c. 1920–50)

, 2023
Milton Quarterly, Volume 57, Issue 3, Page 59-88, October 2023.
Angelica Duran
wiley   +1 more source