Results 11 to 20 of about 1,302,914 (171)

Media Policy Framework for Zimbabwe: a model by MISA-Zimbabwe [PDF]

, 2015
This is a report I helped write for the Media Institute of Southern Africa (MISA) as part of a model media policy framework required by Zimbabwe in the wake of the country's new constitution of 2013. New provisions that have a bearing on the exercise and
Mano, W.
core   +6 more sources

Association of the PD-L1 CPS With the Efficacy of First-Line Nivolumab Plus Chemotherapy for Unresectable Advanced or Recurrent Gastric Cancer. [PDF]

Cancer Med
ABSTRACT Background The CheckMate 649 trial showed the superiority of first‐line nivolumab plus chemotherapy (Nivo‐CT) over chemotherapy alone for advanced gastric or gastroesophageal junction (GEJ) cancer with a programmed cell death‐ligand 1 (PD‐L1) combined positive score (CPS) ≥ 5.
Ogura N, Ohnishi M, Inamoto R, Kito Y, Nagashima K, Takahashi N, Furuta M, Shoji H.   +7 more
europepmc   +2 more sources

Complete Mitochondrial Genome of <i>Porites cylindrica</i> From the Xisha Islands: Characterization and Comparative Mitogenomics of the Genus. [PDF]

Ecol Evol
In this study, we sequenced the dominant species, Porites andrewsi, in the Xisha Islands of the South China Sea, assembled its mitochondrial genome, and analyzed the evolution of the mitochondrial genome of Porites species in combination with 12 other mitochondrial genomes from nine other species.
Jia S, Shen T, Cai W, Zhang J, Wang Y, Cai Z, Shen J, Chen S.   +7 more
europepmc   +2 more sources

Age-specific melanoma risk associated with melanocytic nevi: a pooled analysis from the M-SKIP project. [PDF]

J Dtsch Dermatol Ges
Summary Objective This study investigates the association of melanoma risk with total‐body nevus count and the presence of atypical nevi in younger (< 40 years) and older (> 60 years) individuals. Methods A pooled analysis was conducted within the M‐SKIP project, based on multiple melanoma case‐control studies.
Doi G, Gaeta A, Ribero S, Gruis N, Newton-Bishop J, Polsky D, Lazovich D, Ghiorzo P, Ribas G, Menin C, Stratigos AJ, Guida G, Puig S, Fargnoli MC, Kanetsky PA, Queirolo P, Bagnardi V, Bataille V, Raimondi S, Gandini S, M‐SKIP study group.   +20 more
europepmc   +2 more sources

Two-way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3. [PDF]

FEBS Open Bio
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Ueno R, Terasaki A, Imai Y, Kimura Y, Kojima Y, Irie M, Odaira K, Noura M, Okamoto S, Yasuda T, Tsuzuki S, Kiyoi H, Hayakawa F.   +12 more
europepmc   +2 more sources

Altersspezifisches Melanomrisiko im Zusammenhang mit melanozytären Nävi: Eine gepoolte Analyse aus dem M‐SKIP‐Projekt [PDF]

J Dtsch Dermatol Ges
Zusammenfassung Zielsetzung Diese Studie untersucht den Zusammenhang zwischen dem Melanomrisiko und der Gesamtanzahl der Nävi am Körper sowie dem Vorliegen atypischer Nävi bei jüngeren (< 40 Jahre) und älteren (> 60 Jahre) Personen. Methoden Im Rahmen des M‐SKIP‐Projekts wurde eine gepoolte Analyse auf der Grundlage mehrerer Fall‐Kontroll‐Studien zu ...
Doi G, Gaeta A, Ribero S, Gruis N, Newton‐Bishop J, Polsky D, Lazovich D, Ghiorzo P, Ribas G, Menin C, Stratigos A, Guida G, Puig S, Fargnoli M, Kanetsky P, Queirolo P, Bagnardi V, Bataille V, Raimondi S, Gandini S.   +19 more
europepmc   +2 more sources

The linguistic characterisation of Galdós’s characters in his last play, Santa Juana de Castilla

Orbis Litterarum, Volume 78, Issue 1, Page 45-58, February 2023., 2023
Abstract In this work I propose to examine the linguistic characterisation of the characters in Galdós’s last play, Santa Juana de Castilla (Saint Joanna of Castile, 1918). The analysis will show that in addition to the use of archaic language, the purpose of which may be to evoke the era, the linguistic style of the play is characterised by the use of
Miguel Á. Perdomo‐Batista
wiley   +1 more source

DNA release from plant tissue using focused ultrasound extraction (FUSE)

Applications in Plant Sciences, Volume 11, Issue 1, January-February 2023., 2023
Abstract Premise Sample preparation in genomics is a critical step that is often overlooked in molecular workflows and impacts the success of downstream genetic applications. This study explores the use of a recently developed focused ultrasound extraction (FUSE) technique to enable the rapid release of DNA from plant tissues for genetic analysis ...
Alexia Stettinius, Hal Holmes, Qian Zhang, Isabelle Mehochko, Misa Winters, Ruby Hutchison, Adam Maxwell, Jason Holliday, Eli Vlaisavljevich   +8 more
wiley   +1 more source

EORTC‐QLQ‐C30 and SKINDEX‐29 measurement of health‐related quality of life in patients with mycosis fungoides and Sézary syndrome: Real‐world data in Spanish patients (MICADOS Study)

JEADV Clinical Practice, Volume 1, Issue 4, Page 438-449, December 2022., 2022
Abstract Background Few studies have explored the impact of cutaneous T‐cell lymphoma (CTCL) on health‐related quality of life (HRQoL) and compared it to other patients with cancer. Objectives The primary objective of the study was to assess the QoL of patients diagnosed with the mycosis fungoides (MF) and Sézary syndrome (SS) types of CTCL in Spain ...
Belén Navarro Matilla, Mª del Mar Onteniente Gomis, Ramon M. Pujol Vallverdú, Andrea Combalia Escudero, Irma Zapata Paz, Cristina Muniesa Montserrat, Eva González Barca, Mercedes Morillo Andújar, Amparo Pérez Ferriols, Mª Concepción Román Curto, Ricardo Fernández de Misa Cabrera, Mercedes Hospital Gil, Ana Marín Niebla, Pablo J. Rios Rull, Fátima de la Cruz Vicente, Rosa M. Izu Belloso, Alejandro Martín García‐Sancho, M. Elisabet Parera Amer, Raúl Córdoba Mascuñano, María Dolores Ramón Quiles, Ana Saus Carreres, Raquel del Campo García, Salma Machan, Pablo Viguera Ester, Julia Blanco Garnelo, Begoña Soler López, Pablo L. Ortiz Romero   +26 more
wiley   +1 more source

Phosphorylation of hTERT at threonine 249 is a novel tumor biomarker of aggressive cancer with poor prognosis in multiple organs

The Journal of Pathology, Volume 257, Issue 2, Page 172-185, June 2022., 2022
Abstract Recent evidence indicates that RNA‐dependent RNA polymerase (RdRP) activity of human telomerase reverse transcriptase (hTERT) regulates expression of target genes and is directly involved in tumor formation in a telomere‐independent manner. Non‐canonical function of hTERT has been considered as a therapeutic target for cancer therapy.
Yoko Matsuda, Taro Yamashita, Juanjuan Ye, Mami Yasukawa, Keiko Yamakawa, Yuri Mukai, Mitsuhiro Machitani, Yataro Daigo, Yohei Miyagi, Tomoyuki Yokose, Takashi Oshima, Hiroyuki Ito, Soichiro Morinaga, Takeshi Kishida, Toshinari Minamoto, Shinji Yamada, Junko Takei, Mika K Kaneko, Motohiro Kojima, Shuichi Kaneko, Tsutomu Masaki, Masahiro Hirata, Reiji Haba, Keiichi Kontani, Nobuhiro Kanaji, Nobuyuki Miyatake, Keiichi Okano, Yukinari Kato, Kenkichi Masutomi   +28 more
wiley   +1 more source