Results 131 to 140 of about 28,133 (251)

First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT This guideline summarizes diagnostic and therapeutic approaches based on a systematic literature review and evidence evaluation using the GRADE methodology. Given the limited high‐quality data, expert consensus was additionally obtained through a modified Delphi process.
Giorgia Olivieri, Andrea Bordugo, Birute Burnyte, Alessandro Costetti, Maria‐Luz Couce, Luisa Diogo, Francois Feillet, D. Sean Froese, Benedetta Greco, Jean‐Louis Gueant, Luciana Hannibal, Friederike Hörster, Viktor Kožich, Giancarlo La Marca, Irini Manoli, Fanny Mochel, Lorenzo Orazi, Belén Pérez, Manuel Schiff, Bernd C. Schwahn, Ida Schwartz, Karolina M. Stepien, Jolanta Sykut‐Cegielska, Trine Tangeraas, Rolf H. Zetterström, Carlo Dionisi‐Vici, Martina Huemer   +26 more
wiley   +1 more source

Integrated Reaction Monitoring and In Situ Structural Elucidation of Reactive Intermediates With Time‐Resolved NOAH NMR Supersequences

Magnetic Resonance in Chemistry, Volume 64, Issue 7, Page 621-628, July 2026.
TR‐NOAH‐NUS enables real‐time reaction monitoring and direct structural characterization of transient intermediates. Integration of NOAH supersequences with t0‐filling minimizes reaction monitoring deadtime and provides high temporal resolution for kinetic analysis.
Sara M. Guzman, Yael Ben‐Tal, Jiayu Zhang, Mark Dixon, Jason E. Hein   +4 more
wiley   +1 more source

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

Brain Pathology, Volume 36, Issue 4, July 2026.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña, Enric Vidal, Natalia Fernández‐Borges, Jorge M. Charco, Carlos M. Díaz‐Domínguez, Cristina Sampedro‐Torres‐Quevedo, Josu Galarza‐Ahumada, Eva Fernández‐Muñoz, Maitena San‐Juan‐Ansoleaga, Miguel Ángel Pérez‐Castro, Nuno Gonçalves‐Anjo, Patricia Piñeiro, Samanta Giler, Nora González‐Martín, Nuria L. Lorenzo, Africa Manero‐Azua, Guiomar Perez de Nanclares, Mariví Geijo, Manuel A. Sánchez‐Martín, Jesús R. Requena, Joaquín Castilla   +20 more
wiley   +1 more source

Evaluation of Self-Illuminating Nanoconjugates Against Pancreatic Ductal Adenocarcinoma

International Journal of Nanomedicine
Marcelina Abal-Sanisidro,1– 3 Laura Ruiz-Cañas,4,5 Sandra Batres-Ramos,4,5 Miguel G Blanco,2,6 Maria Laura García-Bermejo,7 Jenifer García-Fernández,1 Luis Rodríguez-Cobo,8,9 Jose Miguel López-Higuera,8– 10 Bruno Sainz Jr,3– 5 María de la Fuente1,3,11 ...
Abal-Sanisidro M, Ruiz-Cañas L, Batres-Ramos S, Blanco MG, García-Bermejo ML, García-Fernández J, Rodríguez-Cobo L, López-Higuera JM, Sainz Jr B, de la Fuente M   +9 more
doaj  

Patch Test Results With the European Baseline Series, 2021/2022—Joint European Results of the ESSCAA and the EBSB Working Groups of the ESCD, and the GEIDACC

Contact Dermatitis, Volume 95, Issue 1, Page 17-32, July 2026.
ABSTRACT Background Patch test results obtained with the European Baseline Series (EBS) in its current version serve both contact allergy surveillance and (re‐)assessing the diagnostic value of EBS allergens. Objectives To present results of current EBS patch testing, obtained in 59 departments in 14 European countries during 2021 and 2022.
Wolfgang Uter, S. Mark Wilkinson, Olivier Aerts, Andrea Bauer, Leopoldo Borrego, Richard Brans, Timo Buhl, Heinrich Dickel, Aleksandra Dugonik, Francesca Larese Filon, Ana Giménez Arnau, Cataldo Patruno, Györgyi Pónyai, Stamatis Gregoriou, Steffen Schubert, Dagmar Simon, Luca Stingeni, Skaidra Valiukevičienė, Elke Weisshaar, Thomas Werfel, Margarida Gonçalo, Marie‐L. A. Schuttelaar, ESSCAA and EBSB ESCD Working Groups, and the GEIDACC , Birger Kränke, Alexander Navarini, Philip Spring, Ulrike Beiteke, Cecilia Dietrich, Sibylle Schliemann, Detlef Becker, Swen Malte John, Nicola Wagner, Dimitra Koumaki, Maddalena Napolitano, Anna Belloni Fortina, Francesca Larese Filon, Rosella Gallo, Thomas Rustemeyer, Radoslaw Spiewak, Maja Kalac Pandurovic, Tanja Kmecl, Mojca Simončič Godnič, Nada Kecelj, Philippa Cousen, Ella Dendooven, Juan Francisco Silvestre Salvador, José Manuel Carrascosa Carrillo, Mónica Munera Campos, Esther Serra Baldrich, Gemma Melé‐Ninot, Cristina Barrabés Torrella, David Pesqué, María Antonia Pastor Nieto, Francisco Navarro Triviño, Inmaculada Ruiz Gonzales, Enrique Gómez de la Fuente, Susana Córdoba Guijarro, Francisco Javier Ortiz de Frutos, Fátima Tous Romero, Tatiana Sanz Sánchez, Pablo Chicharro Manso, Marta Andreu Barasoain, Marta Elosua González, Araceli Sánchez Gilo, Paloma Sánchez‐Pedreño Guillén, Pedro Mercader‐García, Carmen Paredes Suárez, María Elena Gatica Ortega, José Juan Pereyra Rodríguez, Javier Miquel Miquel, Mercedes Rodríguez Serna, Violeta Zaragoza Ninet, Ricardo González Pérez   +73 more
wiley   +1 more source

Genome-Wide DNA Methylation Changes Induced by High-Fat Diet and Methyl Donor Supplementation in Female Lupus Models: An Exploratory Study. [PDF]

Mol Nutr Food Res
A high‐fat diet induces widespread DNA methylation changes in adipose tissue in lupus‐prone mice, while methyl‐donor supplementation (folic acid and vitamin B12) modulates inflammatory pathways, including IL‐17 signaling, in a diet‐dependent manner. ABSTRACT This exploratory study investigated the interactive effects of dietary fat content and methyl ...
Ribeiro AA, Carvalho LM, da Mota JCNL, Souza LL, Pinhel MAS, Nonino CB, Hounkpe BW, Teodoro WPR, Costa-Fraga N, Izquierdo AG, Diaz-Lagares A, Crujeiras AB, Nicoletti CF.   +12 more
europepmc   +2 more sources

Genomic Analysis of Inbreeding Depression on Productive Traits in Rubia Galega Beef Cattle Breed

Journal of Animal Breeding and Genetics, Volume 143, Issue 4, Page 508-523, July 2026.
ABSTRACT In autochthonous livestock breeds with small populations, such as the Rubia Galega from Galicia (Spain), mating between relatives is common and can lead to inbreeding depression. Genomic inbreeding coefficients were estimated for 4984 animals using ~63,000 SNPs to assess inbreeding depression in four key traits: age at first calving (AFC) with
N. Mejuto‐Vázquez, C. Hervás‐Rivero, R. Rodríguez‐Bermúdez, D. López‐Carbonell, M. Hermida, P. Martínez, L. Varona   +6 more
wiley   +1 more source

Evolución urbanística de Santiago de Compostela

Infraestructura de Datos Espaciais (IDE) que representa a evolución urbanística de Santiago de Compostela dende as súas orixes ata o século XIX. Na versión 3 desta publicación poderase descargar esta IDE. Unha vez descargados os arquivos, será importante consultar, primeiro de todo, a lenda da escala cromática de evidencia xerada para este traballo ...
openaire   +2 more sources

Dental Implants in Adults With Intellectual Disabilities: A Multicenter Retrospective Study. Part 1: Implant Outcomes

Journal of Oral Rehabilitation, Volume 53, Issue 7, Page 1259-1274, July 2026.
This multicenter retrospective study evaluated implant survival and peri‐implant health in adults with non‐syndromic intellectual disability. Among 453 implants with long‐term follow‐up, survival exceeded 92%, with tissue‐level implants and cement‐retained restorations associated with healthier peri‐implant conditions. These findings support the use of
Márcio Diniz‐Freitas, Manuel Bratos‐Bobo, Manuel Bratos‐Morillo, Denise Faulks, Marie‐Sophie Bogner, Melanie Derchu, Caroline Eschevins, Emmanuel Nicolas, Pierre Yves Cousson, Chantal Auduc, Yoo Soo‐Yeon, Pedro Diz‐Dios, Pablo Gasamáns‐García, Jacobo Limeres‐Posse, Paolo Appendino, Simone Buttiglieri, Francesco Della Ferrera, Roberto Rozza, Fabio Brusamolino, Javier Fernández‐Feijoo   +19 more
wiley   +1 more source

Knowledge, attitudes and practices regarding antibiotic prescribing by dentists: a qualitative study in Chile. [PDF]

J Public Health (Oxf)
Juárez-Membreño A, Vázquez-Cancela O, Prieto-Campo A, Zapata-Cachafeiro M, Figueiras A, Rodríguez-Fernández A.   +5 more
europepmc   +1 more source