Results 81 to 90 of about 3,587,849 (304)

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

open access: yesAdvanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo   +19 more
wiley   +1 more source

La aristocracia de Castilla y sus abogados celestiales

open access: yesEstudios de Historia de España, 2016
This article studies the relationship between the aristocracy of Castile and the saints as protectors in life and in the time of death. From his last wills and the recommendations contained in the treaties of the genus Ars moriendi, points out the ...
Isabel Beceiro Pita
doaj  

Santos, santos, santos

open access: yes, 1975
"V?zquez Montalb?n, Manuel, 1939-2003" tambi?n ha firmado sus art?culos como "C?mara, Sixto"
openaire   +3 more sources

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

open access: yesAdvanced Science, EarlyView.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun   +14 more
wiley   +1 more source

The virial theorem in Eddington-Born-Infeld gravity

open access: yes, 2015
We consider the possibility that the Eddington-Born-Infeld (EBI) modified gravity provides an alternative explanation for the mass discrepancy in clusters of galaxies.
Santos, Janilo, Santos, Noelia S.
core   +1 more source

Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism

open access: yesAdvanced Science, EarlyView.
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards   +8 more
wiley   +1 more source

A santidade da Igreja em Mathias Joseph Scheeben e nos que nele se inspiraram

open access: yesTeocomunicação, 2006
O estudo do tema da santidade da Igreja e de sua influência na história requer uma análise detalhada e circunstancial a cada período. O século XIX, por exemplo, foi pródigo em dificuldades eclesiais.
Amaral, Miguel de Salis
doaj  

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

open access: yesAdvanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini   +24 more
wiley   +1 more source

EP-240 - MENINGITE POR STREPTOCOCCUS MITIS EM PACIENTE IMUNOCOMPETENTE: RELATO DE CASO

open access: yesBrazilian Journal of Infectious Diseases
Introdução: Streptococcus mitis é uma bactéria do grupo viridans, que pode ser encontrada na flora normal da orofaringe, trato genital feminino, trato gastrointestinal e pele.
Maria Eduarda Oliveira Onuki   +6 more
doaj   +1 more source

Structure of ternary additive hard-sphere fluid mixtures

open access: yes, 2002
Monte Carlo simulations on the structural properties of ternary fluid mixtures of additive hard spheres are reported. The results are compared with those obtained from a recent analytical approximation [S. B. Yuste, A. Santos, and M.
A. Santos   +29 more
core   +1 more source

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