Results 191 to 200 of about 513,035 (306)

Biomolecular Interaction Prediction in the Pre‐ and Post‐AlphaFold Era: The 8th CAPRI Evaluation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We report on the 8th CAPRI Evaluation period, capturing the assessment of CAPRI Rounds 47 to 55 (excluding the CASP and COVID‐related Rounds), which have witnessed the transition to AI‐driven prediction tools such as AlphaFold and related alternatives. The prediction Rounds in this evaluation are characterized by a high level of difficulty due
Marc F. Lensink, Nessim Raouraoua, Guillaume Brysbaert, Sameer Velankar, Shoshana J. Wodak, Alexandre M. J. J. Bonvin   +5 more
wiley   +1 more source

Visual Field Stability After Trifocal Intraocular Lens Implantation: A Longitudinal Standard Automated Perimetry Study. [PDF]

Clin Ophthalmol
Hida WT, Da Silva MGB, Moscovici BK, Vilar C, Campos PTS, Gouvea L, Chow M, Tzelikis PFM, Chaves MAPD, Motta AFP, Lake JC, Carricondo PC.   +11 more
europepmc   +1 more source

Performance of pyDock in 8th CAPRI: Energy‐Based Scoring Applied to Docking and AlphaFold Models

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The 8th CAPRI edition has shown a significant evolution in the field of protein–protein complex structure prediction. We have participated in all 11 targets proposed in this edition, involving domain‐domain, protein–protein, protein‐peptide, and protein‐DNA interactions, including homo‐ and hetero‐meric interfaces.
Luis Angel Rodríguez‐Lumbreras, Mireia Rosell, Miguel Romero‐Durana, Víctor Monteagudo, Fabian Glaser, Juan Fernandez‐Recio   +5 more
wiley   +1 more source

Ankh‐Score Produces Better Sequence Alignments Than AlphaFold3

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Protein sequence alignment is one of the most fundamental procedures in bioinformatics. Due to its many downstream applications, improvements to this procedure are of great importance. We consider two revolutionary concepts that emerged recently as candidates for improving the state‐of‐the‐art alignment methods: AlphaFold and protein language ...
Julia Malec, Karina Rusen, G. Brian Golding, Lucian Ilie   +3 more
wiley   +1 more source

Impaired Autophagic Flux in Adipose Tissue Aggravates Pancreatic Injury in Obesity-Related Severe Acute Pancreatitis. [PDF]

Immun Inflamm Dis
Sheng LP, Shang GC, Han CQ, Ling X, Guo XW, Lin R, Ding Z.   +6 more
europepmc   +1 more source

Bacillus thuringiensis and its pest control potential as endophyte

Pest Management Science, EarlyView.
Bacillus thuringiensis (Bt) systemically colonizes tomato plants as endophyte, inducing midgut damage, fitness reduction and immune suppression in Spodoptera littoralis larvae feeding on Bt‐colonized leaves. The immune suppression enhances the susceptibility to Bt treatments, allowing a synergistic dual use of Bt commercial formulations, by combined ...
Maria Giovanna De Luca, Giovanni Jesu, Daniele Bruno, Elia Russo, Andrea Becchimanzi, Gianluca Tettamanti, Maria Cristina Digilio, Ilaria Di Lelio, Francesco Pennacchio   +8 more
wiley   +1 more source

Effect of Self-Assembling Peptide on White Spot Lesions in Orthodontic Patients: A Systematic Review and Meta-Analysis. [PDF]

Clin Exp Dent Res
Shakir S, Umer F, Khalid Q, Shahzad K, Hussain U, Mohammad S, Omair H, Campobasso A, Naseem W, Khan J.   +9 more
europepmc   +1 more source

Rhizobacteria regulate colonising Sitobion avenae aphid populations through induced host resistance and alter plant volatiles promoting early parasitoid recruitment on barley (Hordeum vulgare)

Pest Management Science, EarlyView.
Rhizobacterial inoculation of barley reduced Sitobion avenae populations by inducing plant resistance and modifying volatiles that attracted parasitoid wasps earlier, enhancing both bottom‐up and top‐down pest control. Abstract BACKGROUND Soil rhizobacteria can enhance crop resistance to insect herbivores and influence higher trophic interactions ...
Megan E Parker, Angharad M R Gatehouse, Sharon E Zytynska   +2 more
wiley   +1 more source

Evaluating the remineralisation potential and clinical evidence of emerging biocompatible materials in restorative dentistry: a systematic review. [PDF]

Biomater Investig Dent
Isaiselvi D, Indumathi KP, Sibyl S, Krishnaprakash G.   +3 more
europepmc   +1 more source

HvarAKR1B1‐mediated tolerance in Hippodamia variegata: Deciphering the metabolic adaptation and fitness costs under prolonged starvation

Pest Management Science, EarlyView.
Starvation stress significantly affected the growth and development of Hippodamia variegata. Combined transcriptome and metabolome analysis and RNA interference verification revealed that HvarAKR1B1 may be involved in the response of Hippodamia variegata to starvation stress.
Bing‐mei Song, De‐qin Hu, Yuan Li, Wang‐quan Jiao, Xiao‐li Ma, Hong‐sheng Pan   +5 more
wiley   +1 more source