Results 51 to 60 of about 513,035 (306)

Safety of the Deferral of Coronary Revascularization on the Basis of Instantaneous Wave-Free Ratio and Fractional Flow Reserve Measurements in Stable Coronary Artery Disease and Acute Coronary Syndromes. [PDF]

, 2018
OBJECTIVES: The aim of this study was to investigate the clinical outcomes of patients deferred from coronary revascularization on the basis of instantaneous wave-free ratio (iFR) or fractional flow reserve (FFR) measurements in stable angina pectoris ...
Al-Lamee, R, Alegria-Barrero, E, Alghamdi, A, Altman, J, Ambrosia, A, Baptista, SB, Bertilsson, M, et al., Cook, CM, Dehbi, HM, Escaned, J, Mejía-Rentería, H, Ryan, N   +11 more
core   +1 more source

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

Advanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou, Yongfeng Chen, Longyou Xiao, Wei Qi, Tianshu Du, Qiang Sun, Borui Xue, Qinghe Zhao, Pengfei Xie, Zi Ye, Fei Han, Lingli Guo, Yang Jiao, Ranran Zhang, Hong Jia, Xiao Huang, Jianwei Guo, Peng Wang, Huayi Wang, Yuanrui Wang, Wenjing Chen, Haining Wu, Liumin He, Dawei Zhang   +23 more
wiley   +1 more source

Bifidobacterium Pseudolongum‐Derived Acetate Attenuates Acute Pancreatitis Through GPR43‐Mediated Suppression of M1 Macrophage Polarization

Advanced Science, EarlyView.
The severity of acute pancreatitis (AP) is linked to reduced abundance of Bifidobacterium pseudolongum (B. pseudolongum). Administration of B. pseudolongum or its key metabolite acetate alleviates pancreatic and systemic inflammation by suppressing M1 macrophage polarization.
Langyi Guan, Xueyang Li, Cong He, Pan Zheng, Yaoyu Zou, Qi Zhu, Xin Li, Jie Liang, Junmin Yang, Li Zhang, Yuman Ye, Jianhua Wan, Huajing Ke, Jianping Liu, Nonghua Lu, Nianshuang Li, Yin Zhu   +16 more
wiley   +1 more source

Enhancement of the UK Standard Assessment Procedure (SAP) solar water heating prediction algorithm using parametric dynamical thermal simulations [PDF]

, 2011
SAP is the UK Government’s method for calculation of a dwelling’s energy efficiency and carbon dioxide emissions. This paper presents a method of informing the SAP procedure regarding evaluation of the advantage given to SAP ratings by installation of ...
Counsell, John, Murphy, Gavin Bruce, Samuel, Aizaz Aamir   +2 more
core  

CD28‐Targeted Enzyme‐Responsive Conformation‐Switching Peptide Self‐Assembly for Selective T‐Cell Acute Lymphoblastic Leukemia (T‐ALL) Therapy

Advanced Science, EarlyView.
We developed the enzyme‐responsive peptide SAp‐CD28 to selectively target CD28‐overexpressing T‐ALL cells. Following phosphatase‐mediated activation, SAp‐CD28 undergoes conformational switching and nanooligomerization, resulting in the disruption of CD28 downstream signaling.
Jun Li, Ziyu Jia, Dekun Li, Zhi‐Wen Hu, Yinghao Ding, Shengyi Zhang, Shengkun Tuo, Zhimou Yang, Huisheng Fu, Ling Wang, Man‐Di Wang   +10 more
wiley   +1 more source

Bioprinted Tumor Microenvironment Models Reveal Immune Evasion and Guide CAR‐NK Therapeutic Strategies

Advanced Science, EarlyView.
This study presents a 3D embedded bioprinting platform that recapitulates key stromal features of the tumor microenvironment using fibroblasts and lung‐derived ECM. The model enables functional assessment of CAR‐NK cells and provides a versatile tool to support the development of next‐generation immunotherapeutic strategies against solid tumors ...
Dahong Kim, Seona Jo, In‐Hwan Jang, Yu‐Jin Kim, Youngmee Jung, Junhyoung Ahn, Hyungjun Lim, Jae Jong Lee, Kangwon Lee, Tae‐Don Kim, Su A Park   +10 more
wiley   +1 more source

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

Advanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

On the Dominance of Trivial Knots among SAPs on a Cubic Lattice

, 2001
The knotting probability is defined by the probability with which an $N$-step self-avoiding polygon (SAP) with a fixed type of knot appears in the configuration space. We evaluate these probabilities for some knot types on a simple cubic lattice. For the
Akihisa Yao, Deguchi T, Deguchi T, Deguchi T, Deguchi T, Delbrück M, desCloizeaux J, Guida R, Guttmann A J, Hiroshi Matsuda, Hiroshi Tsukahara, Janse van Rensburg E J, Janse vanRensburg E J, Klenin K V, LeBret M, LeGuillou J C, LeGuillou J C, Li B, Lipkin M, Madras N, Madras N, Miyuki K Shimamura, Orlandini E, Orlandini E, Soteros C E, Sumners D W, Tesi M C, Tetsuo Deguchi, Vologodskii A V, Whittington S G   +29 more
core   +1 more source

Ultrafast Dynamics of Spin Current and Electron Temperature in Spintronic Terahertz Emitters

Advanced Science, EarlyView.
This work quantifies optical‐pump‐induced THz transmission variations to reveal electron and lattice temperature dynamics and presents time‐resolved THz spectral maps for sub‐picosecond analysis. A 63 ± 8 fs time lag between THz emission and laser excitation is identified, serving as an intrinsic parameter limiting the upper frequency of spintronic THz
Yifan Wang, Zuanming Jin, Miao Cai, Zhiqiang Lan, Zhenjie Ge, Zheng Feng, Wei Tan, Alexei V. Balakin, Alexander P. Shkurinov, Yan Peng, Yiming Zhu   +10 more
wiley   +1 more source

The Value of RANSON Score Combined with BMI in Predicting the Mortality in Severe Acute Pancreatitis: A Retrospective Study

International Journal of General Medicine, 2022
Xu Yin,1 Xiang Zhong,2 Jun Li,1 Ma Le,1 Shiting Shan,1 Chunfu Zhu1 1Department of Hepatobiliary and Pancreatic Surgery, Changzhou No.2 People’s Hospital Affiliated with Nanjing Medical University, Changzhou, Jiangsu, 213000, People’s Republic of China ...
Yin X, Zhong Z, Li J, Le M, Shan S, Zhu C   +5 more
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