Results 61 to 70 of about 582,334 (336)

eNOS transfection of adipose-derived stem cells yields bioactive nitric oxide production and improved results in vascular tissue engineering. [PDF]

, 2015
This study evaluates the durability of a novel tissue engineered blood vessel (TEBV) created by seeding a natural vascular tissue scaffold (decellularized human saphenous vein allograft) with autologous adipose-derived stem cells (ASC) differentiated ...
Bagameri, Gabor, Comeau, Jason, DiMuzio, Paul J., Faul, Elizabeth J, Fernandez, Sarah, Ferroni, Matthew, McIlhenny, Stephen, Policha, Aleksandra, Shapiro, Irving, Tulenko, Thomas, Zhang, Ping   +10 more
core   +2 more sources

Peptide Amphiphiles Hitchhike on Endogenous Biomolecules for Enhanced Cancer Imaging and Therapy

Advanced Materials, EarlyView.
Weakly assembled peptide amphiphile nanostructures disassemble in circulation and reassemble with blood biomolecules, mainly lipoproteins. Binding to blood biomolecules prolongs blood circulation and improves accumulation in solid tumors. In the tumor microenvironment, peptide amphiphiles assemble with cholesterol‐rich domains of cell membranes ...
Li Xiang, Morgan R. Stewart, Kailin Mooney, Mingchong Dai, Samuel Drennan, Samantha Holland, Arnaud Quentel, Sinan Sabuncu, Benjamin R. Kingston, Isabel J. Dengos, Karla Bonic, Florian Goncalves, Xin Yi, Michael I. Henderson, Srivathsan Ranganathan, Bruce P. Branchaud, Leslie L. Muldoon, Ramon F. Barajas Jr, Jared M. Fischer, Adem Yildirim   +19 more
wiley   +1 more source

Fatty acids composition of aorta and saphenous vein tissues in patients with coronary artery diseases [PDF]

Journal of Cardiovascular and Thoracic Research, 2017
Introduction: Considering importance of fatty acids in developing coronary artery disease (CAD) and lack of information about saphenous vein which is commonly used as coronary arterial bypass, in this study we investigated differences in fatty acids ...
Mirhamid Paytakhti Oskouei, Masoud Pezeshkian, Naser Safaie, Masoud Darabi, Amir Fattahi, Hossain Bijanpour, Maghsod Shaaker, Ahmad Reza Jodati, Mohammad Nouri   +8 more
doaj   +1 more source

Short Term Fate of Great Saphenous Vein after Radiofrequency Ablation for Varicose Veins.

Kathmandu University Medical Journal, 2017
Background Radiofrequency ablation of varicose vein have gained popularity compared to conventional surgery due to comparable long term results in addition to definite immediate superiorities. This modality has been started in Nepal since August 2003 and
R. Karmacharya, M. Devbhandari, Y. Shakya   +2 more
semanticscholar   +1 more source

FMO2 Promotes Angiogenesis via Regulation of N‐Acetylornithine

Advanced Science, EarlyView.
This study identifies flavin‐containing monooxygenase 2 (FMO2) as a novel proangiogenic regulator in endothelial cells. Targeted FMO2 ablation impairs vessel sprouting, whereas its compensation potently enhances angiogenesis. Metabolomics and single‐cell sequencing reveal that FMO2 drives vascular growth via the N‐acetylornithine/ATF3/NOTCH1 axis ...
Jingyi Wang, Yinghui Xu, Xianpeng Wu, Mo Li, Changchen Xiao, Zaiyang Fu, Yongjian Chen, Qingju Li, Yating Ruan, Jing Zhao, Zhiwei Zhong, Jinghai Chen, Wei Zhu, Jinliang Nan, Cheng Ni, Xinyang Hu   +15 more
wiley   +1 more source

Upregulation of miR-126-3p promotes human saphenous vein endothelial cell proliferation in vitro and prevents vein graft neointimal formation ex vivo and in vivo

OncoTarget, 2017
Poor long-term patency of vein grafts remains an obstacle in coronary artery bypass grafting (CABG) surgery using an autologous saphenous vein graft. Recent studies have revealed that miR-126-3p promotes vascular integrity and angiogenesis.
Qingxi Qu, W. Bing, Xiangbin Meng, Jie Xi, X. Bai, Qing Liu, Yaqiu Guo, Xin Zhao, Y. Bi   +8 more
semanticscholar   +1 more source

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

Advanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang, Xinran Ye, Chia‐Kang Ho, Ya Gao, Dongsheng Wen, Jiaming Sun, Yuxin Liu, Yangdan Liu, Guoyuan Wang, Yangbai Sun, Jinyan Zhang, Yifan Zhang, Qingfeng Li   +12 more
wiley   +1 more source

Predictive factors of late venous aortocoronary graft failure: ultrastructural studies. [PDF]

PLoS ONE, 2013
BACKGROUND: Venous aortocoronary graft arterialization may precede a preterm occlusion in some coronary artery bypass grafting (CABG) patients. The aim of the present study was to identify ultrastructural variations in the saphenous vein wall that may ...
Bartlomiej Perek, Agnieszka Malinska, Sebastian Stefaniak, Danuta Ostalska-Nowicka, Marcin Misterski, Maciej Zabel, Anuj Suri, Michal Nowicki   +7 more
doaj   +1 more source

The role of p53 in atherosclerosis [PDF]

, 2006
Although the role of the tumour suppressor gene p53 is well known in cancer, recent studies have highlighted a fundamental role for p53 in regulating cells in the advanced atherosclerotic plaque, the major cause of heart attacks and stroke. In particular,
Bennett, M., Mercer, J.R.
core   +1 more source

Neuronal Endothelin a Receptor Mediates Experimental and Clinical Vascular Pain through an Endothelial‐Neural Axis

Advanced Science, EarlyView.
The authors develop mouse models by mimicking peripheral vascular diseases, combining multiple strategies and transgenic mouse lines, to demonstrate that ECs, but not macrophages or SMCs, play an active role mediated by endothelial ET‐1/neural ETAR signaling and beyond endothelial homeostatic angiocrine by driving protective pain through the ...
Zuo‐Jie Jiang, Di Mu, Su Liu, Peng‐Bo Jing, Bin Wu, Xiao‐Mei Yang, Jia‐Yi Ge, Qing‐Yi Li, Hao‐Hao Chen, Feng‐Ming Zhang, Bing Wang, Ying‐Ying Zhang, Linnan Qian, Zi‐Yi Zhu, Yu‐Sen Ou, Shi‐Yu Sun, Lin Luo, Yu Feng, Changyu Jiang, Zhuo Sun, Yong Chen, Hai‐Li Pan, Bin Wang, Fen‐Fei Gao, Jie Wu, Zhigang Lu, Tong Liu, Yan‐Gang Sun, Xing‐Jun Liu   +28 more
wiley   +1 more source