Results 271 to 280 of about 770,289 (341)

Holistic Optimization toward Ultrathin Flexible Perovskite Solar Cells with High Efficiency and Mechanical Robustness

open access: yesAdvanced Science, EarlyView.
In this manuscript, 2D perovskite grain boundaries are constructed to improve the intrinsic flexibility of perovskite films by efficiently releasing the strain. In addition, a novel additive, sucralose, is employed to enhance the conductivity and mechanical flexibility of PEDOT:PSS electrodes. Consequently, an ultrathin f‐PSC is successfully fabricated
Guanqi Tang   +5 more
wiley   +1 more source

Enhanced Activities of OCT4 and SOX2 Promote Epigenetic Reprogramming by Shortening G1 Phase

open access: yesAdvanced Science, EarlyView.
Fusing the VP16 domain to OCT4 and SOX2 (OvSvK) enhances iPSC generation by activating downstream targets, including those regulating the cell cycle. This accelerates reprogramming by shortening the G1 phase and reducing H3K27me3 levels. Modulating Ccnd1, Cdkn2a, and Ccne1 improves efficiency, linking cell cycle to epigenetic remodeling.
Lin Guo   +17 more
wiley   +1 more source

Single‐Cell Analysis Clarifies Pathological Heterogeneity in Tenosynovial Giant Cell Tumor and Identifies Biomarkers for Predicting Disease Recurrence

open access: yesAdvanced Science, EarlyView.
MP3 tumor cells, a specific subpopulation of tumor cells in D‐TGCT, regulated the differentiation of CD34+ Fbs into MMP3+ Fbs and APOE+ Fbs through COL6A3 − (ITGAV + ITGB8) interaction. APOE+ Fbs activated IL‐1B+CCL20+ Mφs through the CXCL12/CXCR4 axis. IL‐1B+CCL20+ Mφs and MMP3+ Fbs participated in the local invasion of D‐TGCT.
Yubin Xie   +15 more
wiley   +1 more source

Engineering Light‐Element Modified LaFe11.6Si1.4 Compounds Enables Tunable Giant Magnetocaloric Effect

open access: yesAdvanced Science, EarlyView.
Herein, a tunable magnetocaloric effect is achieved on a series of light elements (C, F, S) modified LaFe11.6Si1.4 compounds. It is found that interstitial doping is more efficient in shifting TC compared with mixed (substitutional/interstitial) doping, but the first‐order transition cannot be well kept because of different p–d hybridization.
Fengqi Zhang   +13 more
wiley   +1 more source

DAP12-associated synthetic antigen receptors enable multi-targeting of T cells with independent chimeric receptors in a small genetic payload. [PDF]

open access: yesiScience
Moore AE   +10 more
europepmc   +1 more source

Trustworthy Inverse Molecular Design via Alignment with Molecular Dynamics

open access: yesAdvanced Science, EarlyView.
Data‐driven inverse molecular design (IMD) is a promising approach to discovering new molecules with desired properties. Despite the remarkable progress, existing IMD methods lag behind in terms of trustworthiness, as indicated by their misalignment with the ground‐truth function that models the molecular dynamics.
Kevin Tirta Wijaya   +3 more
wiley   +1 more source

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