Results 141 to 150 of about 2,045,084 (313)

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo   +10 more
wiley   +1 more source

Spaceborne Radar Technologies for Earth Remote Sensing [PDF]

open access: yes, 2007
Synthetic Aperture Radar (SAR) is an indispensable source of information in earth observation since SAR is the only spaceborne sensor that has highresolution, all-weather and day-and-night imaging capability.
Moreira, Alberto
core  

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

open access: yesAdvanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer   +17 more
wiley   +1 more source

Radiologically detected intranodal thyroid tissues in ipsilateral cervical lymph nodes after hemithyroidectomy in a pediatric patient

open access: yesRadiology Case Reports
This case report illustrates the presence of intranodal thyroid tissues in ipsilateral cervical lymph nodes after hemithyroidectomy for multinodular goiter in an adolescent patient.
Wai Kit Kung, MBBS, FRCR   +3 more
doaj   +1 more source

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang   +11 more
wiley   +1 more source

Bi- and Multistatic SAR: Potentials and Challenges [PDF]

open access: yes, 2004
Bi- and multistatic synthetic aperture radar (SAR) operates with distinct transmit and receive antennas which are mounted on separate platforms. Such a spatial separation has several operational advantages which will increase the capability, reliability ...
Moreira, Alberto   +2 more
core  

Home - About - Disclaimer - Privacy