Results 191 to 200 of about 4,108,289 (262)

Mutant KRAS‐m6A Epitranscriptome Axis Promotes Colorectal Cancer and is a Therapeutic Target

Advanced Science, EarlyView.
Mutant KRAS‐m6A axis promotes colorectal cancer (CRC) progression. Mutant KRAS stabilizes METTL3, leading to increased m6A‐modified BCL9L mRNA and translation of BCL9L protein. BCL9L in turn mediates TGF‐β secretion to induce differentiation of Treg and an immunosuppressive microenvironment.
Danyu Chen, Pingmei Huang, Ruizhi Tao, Fenfen Ji, Qinyao Wei, Lok Hin Ko, Lianxin Zhou, Huarong Chen, Alvin Cheung, Wei Kang, Ko Fai To, Jun Yu, Chi Chun Wong   +12 more
wiley   +1 more source

Comparison between ^99mTcO₄ ^- SPECT/CT and diagnostic ¹³¹I SPECT/CT for the detection of postoperative thyroid remnant in patients with differentiated thyroid cancer. [PDF]

Quant Imaging Med Surg
Zhang R, Yang H, Zou Y, Zhao Y, Shen R, Zhang Z.   +5 more
europepmc   +1 more source

Deciphering Structure‐Bubble‐Mass Transfer Relationships in Water Electrolysis Through Electrode Morphology Regulation

Advanced Science, EarlyView.
Electrode morphology is shown to govern oxygen‐bubble dynamics and interfacial mass transfer during water electrolysis. Positive‐curvature nanoneedles promote rapid release of small bubbles, sustain electrolyte renewal, and minimize mass‐transport losses, whereas flat and concave architectures increasingly retain bubbles.
Zhiqing Tang, Ziyun Zhang, Huicun Gu, Baoxin Wu, Kejun Yan, Jiahui Luo, Yuting Jiang, Cailin Xiao, Yu Xu, Lin Zeng   +9 more
wiley   +1 more source

Deciphering the Medicinal Chemistry Aspects of Akt Inhibitors for the Management of Cancer: Structure-Activity Relationship Frameworks, Landscapes, and Optimization Approaches. [PDF]

Chem Biodivers
Dhangar MS, Palkar MB.
europepmc   +1 more source

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

Advanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng, Xiaochun Chen, Wei Li, Shu Tang, Jun Zhou, Xia Wu, Dan Yuan, Zhongyan Shan, Junfeng Shi   +8 more
wiley   +1 more source

A Distributed 4-Port Hilbert Slot MIMO Antenna with Full-Body Phantom Validation for mmWave Wearable Telemetry. [PDF]

Sensors (Basel)
Saleh S, Saeidi T, Timmons N.
europepmc   +1 more source

Raman Analysis of RNA Nucleotide Strands From SARS‐CoV‐2 Variants and Subvariants: A Step Forward in the Definition of “Raman Genome”

Advanced Science, EarlyView.
Main Raman signals in RNA, related to helical backbone, ribofuranose ring, and nitrogenous bases, are affected by secondary structures that cause hyperchromic effects and significantly alter the Raman intensity. ABSTRACT Raman spectra of RNA nucleotide strands extracted from 20 SARS‐CoV‐2 strains, including the original Japanese isolate, Alpha, Beta ...
Giuseppe Pezzotti, Yoshiki Yasukochi, Gianluca Angiola, Takaharu Ueno, Saki Ikegami, Rintaro Okawa, Tetsuya Adachi, Wenliang Zhu, Osam Mazda, Alfio Grillo, Koichiro Higasa, Kazu Okuma   +11 more
wiley   +1 more source

Optimal seamline detection for SAR image mosaicking guided by superpixel segmentation and region merging. [PDF]

PLoS One
Yan D, Zeng F, Chen B, Huang R, She Y.
europepmc   +1 more source

FAM134B Restricts African Swine Fever Virus Capsid Assembly via Reticulophagy and Its Antiviral Activity is Antagonized by the Viral Virulence‐Associated Factor pMGF300‐2R

Advanced Science, EarlyView.
ABSTRACT African swine fever (ASF), caused by African swine fever virus (ASFV), is a devastating viral disease in domestic pigs and wild boar. ASFV is a large DNA virus whose capsid assembly takes place within perinuclear viral factories (VFs). Accumulating evidence has demonstrated that reticulophagy confers antiviral activity against multiple RNA ...
Rui Luo, Jing Zhang, Ruojia Huang, Xianfeng Zhang, Lian‐Feng Li, Jing Lan, Zhanhao Lu, Yuan Sun, Tao Wang, Hua‐Ji Qiu   +9 more
wiley   +1 more source

LG-RSD: local-global region self-distillation for robust SAR ship detection. [PDF]

Sci Rep
Jing Z, Yan Z.
europepmc   +1 more source