Results 31 to 40 of about 4,108,289 (262)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

A weighted least squares solution for space intersection of spaceborne stereo SAR data [PDF]

, 2001
The use of stereoscopic SAR images offers an alternative to interferometric SAR for the generation of digital elevation models (DEMs). The stereo radargrammetric method is robust and can generate DEMs of sufficient accuracy to geocode SAR images ...
Dowman, I.J., Ian J. Dowman, Pu-huai Chen, Chen, P.-H.   +3 more
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Current understanding of the molecular mechanisms of chemotherapy-induced peripheral neuropathy

Frontiers in Molecular Neuroscience
Chemotherapy-induced peripheral neuropathy (CIPN) is the most common off-target adverse effects caused by various chemotherapeutic agents, such as cisplatin, oxaliplatin, paclitaxel, vincristine and bortezomib. CIPN is characterized by a substantial loss
Xinyu Chen, Yumeng Gan, Ngan Pan Bennett Au, Ngan Pan Bennett Au, Ngan Pan Bennett Au, Chi Him Eddie Ma   +5 more
doaj   +1 more source

F-SAR – DLR’s advanced airborne SAR system onboard DO228 [PDF]

, 2008
The Microwaves and Radar Institute of the German Aerospace Center (DLR) is known for its consistent work on the field of airborne synthetic aperture radar and its application.
Nottensteiner, Anton, Rolf Scheiber, Anton Nottensteiner, Horn, Ralf, Ralf Horn, Scheiber, Rolf   +5 more
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Mechanisms of the electron density depletion in the SAR arc region [PDF]

Annales Geophysicae, 1996
This study compares the measurements of electron density and temperature and the integral airglow intensity at 630 nm in the SAR arc region and slightly south of this (obtained by the Isis 2 spacecraft during the 18 December 1971 magnetic storm), with
A. V. Pavlov
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

An Improved GLRT Method for Target Detection in SAR Imagery

MATEC Web of Conferences, 2015
Automatic ground vehicle detection based on SAR imagery is one of the important military applications of SAR. A region-based generalized likelihood ratio test (GLRT) method is proposed in this paper, and this method combines the GLRT detection theory and
Ju Yingyun, Fu Peng, Zhou Xin, Peng Rongkun   +3 more
doaj   +1 more source

Analysis and Simulation on Imaging Performance of Backward and Forward Bistatic Synthetic Aperture Radar

Remote Sensing, 2018
In recent years, bistatic synthetic aperture radar (SAR) technique has attracted considerable and increasing attention. Compared to monostatic SAR for which only the backscattering is measured, bistatic SAR expands the scattering measurements in aspects ...
Tingting Li, Kun-Shan Chen, Ming Jin
doaj   +1 more source