Results 21 to 30 of about 1,181,994 (188)

Ingesting a pre-workout supplement containing caffeine, B-vitamins, amino acids, creatine, and beta-alanine before exercise delays fatigue while improving reaction time and muscular endurance

open access: yesNutrition & Metabolism, 2012
Background The purpose of this study was to determine the effects of the pre-workout supplement Assault™ (MusclePharm, Denver, CO, USA) on upper and lower body muscular endurance, aerobic and anaerobic capacity, and choice reaction time in recreationally-
Spradley Brandon D   +7 more
doaj   +1 more source

Mitofusin-2 stabilizes adherens junctions and suppresses endothelial inflammation via modulation of β-catenin signaling

open access: yesNature Communications, 2021
Endothelial tissues must have intact barrier function, but this may be disrupted during inflammation. Here, the authors show that the mitochondrial protein Mitofusin-2 stabilizes cell–cell adherens junctions in endothelial cells during homeostasis and ...
Young-Mee Kim   +7 more
doaj   +1 more source

Diagnostic Yield of Sequencing in Prenatal Agenesis of the Corpus Callosum in a Well‐Phenotyped International Cohort

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective To evaluate the incremental diagnostic yield of sequencing in a large, well‐phenotyped international cohort of fetuses with prenatally diagnosed agenesis of the corpus callosum (ACC) and to identify associated genes and variants. Methods Retrospective multicenter cohort study of fetuses with a prenatal diagnosis of ACC undergoing ...
Lorraine Dugoff   +18 more
wiley   +1 more source

Lactate overload inhibits myogenic activity in C2C12 myotubes

open access: yesOpen Life Sciences, 2019
Lactate (LA), an endogenous metabolite produced from pyruvate, can accumulate in skeletal muscle in certain conditions including major diseases, as well as during intensive exercise.
Oh Sarah Se-Jung   +4 more
doaj   +1 more source

Whole Transcriptome Analyses Reveal Differential mRNA and microRNA Expression Profiles in Primary Human Dermal Fibroblasts Infected with Clinical or Vaccine Strains of Varicella Zoster Virus

open access: yesPathogens, 2019
Licensed live attenuated vaccines have been developed to prevent varicella zoster virus (VZV) infection, which causes chickenpox and shingles. The genomic sequences of both clinical- and vaccine-derived VZV strains have been analyzed previously.
Soo-Jin Oh   +5 more
doaj   +1 more source

STRATIFIED ADAPTATION: Infrastructure, Elevation, and Cascading Floods in the Urban Mekong Delta

open access: yesInternational Journal of Urban and Regional Research, EarlyView.
Abstract Flood‐prone cities in the global South are increasingly the target of infrastructure projects aimed at building climate ‘resilience’. At the same time, residents of these cities take adaptation to flooding into their own hands. In this article we examine the interrelationship between household‐scale and urban‐scale flood mitigation projects in
Lizzie Yarina   +3 more
wiley   +1 more source

Staffing Leverage at the Audit Office and Audit Quality L'influence de la dotation en personnel des bureaux d'audit sur la qualité des audits

open access: yesContemporary Accounting Research, EarlyView.
ABSTRACT The PCAOB posits that audit partner and manager involvement, primarily through greater supervision and review (“oversight”) of audit engagements, is an important determinant and indicator of audit quality. We test this notion by empirically examining the link between staffing leverage, as measured by an office's ratio of audit partners and ...
Joshua A. Khavis   +2 more
wiley   +1 more source

Patient‐reported outcomes, postoperative pain and pain relief after day‐case surgery (POPPY): acute pain and recovery during the first 7 days

open access: yesAnaesthesia, EarlyView.
Summary Introduction The majority of surgical cases in the UK occur in a day‐case setting. Published short‐term follow‐up studies after day‐case surgery are lacking and patterns of recovery including pain and patient reported outcome measures, are largely unknown. Methods Data from the Patient‐reported Outcomes, Postoperative Pain and pain relief after
Matthew Everson   +2177 more
wiley   +1 more source

TBX3 regulates splicing in vivo: a novel molecular mechanism for Ulnar-mammary syndrome.

open access: yesPLoS Genetics, 2014
TBX3 is a member of the T-box family of transcription factors with critical roles in development, oncogenesis, cell fate, and tissue homeostasis. TBX3 mutations in humans cause complex congenital malformations and Ulnar-mammary syndrome.
Pavan Kumar P   +7 more
doaj   +1 more source

Speech patterns and enunciation for encephalopathy determination—A prospective study of hepatic encephalopathy

open access: yesHepatology Communications, 2022
Hepatic encephalopathy (HE) is a complication of cirrhosis that benefits from early diagnosis and treatment. We aimed to characterize speech patterns of individuals with HE to investigate its potential to diagnose and monitor HE. This was a single‐center
Andrew M. Moon   +7 more
doaj   +1 more source

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