Results 171 to 180 of about 10,579 (221)

Analysis of IgG responses to Sarcocystis neurona in horses with equine protozoal myeloencephalitis (EPM) suggests a Th1-biased immune response.

Veterinary Immunology and Immunopathology
Equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona is one of the most important neurological diseases of horses in the Americas. While seroprevalence of S. neurona in horses is high, clinical manifestation of EPM occurs in less than 1 
Catherine J. Angwin, Izabela de Assis Rocha, S.M Reed, Jennifer K. Morrow, A. Graves, Daniel K. Howe   +5 more
semanticscholar   +1 more source

Penetration of equine leukocytes by merozoites of Sarcocystis neurona

Veterinary Parasitology, 2006
Horses are considered accidental hosts for Sarcocystis neurona and they often develop severe neurological disease when infected with this parasite. Schizont stages develop in the central nervous system (CNS) and cause the neurological lesions associated with equine protozoal myeloencephalitis.
David S, Lindsay, Sheila M, Mitchell, Jibing, Yang, J P, Dubey, Robert M, Gogal, Sharon G, Witonsky   +5 more
openaire   +2 more sources

Characterization of SnROP9, a rhoptry protein homologue of Sarcocystis neurona that is expressed in lifecycle stages lacking rhoptry organelles.

International Journal of Parasitology
Proteins released by the club-shaped, apically located, specialized secretory organelles called rhoptries play an essential role in host cell invasion and intracellular survival of apicomplexans.
A. Jegatheesan, Margaret Micciche, Jennifer Ngo, P. Bradley, Daniel K. Howe, S. Dangoudoubiyam   +5 more
semanticscholar   +1 more source

Viability of Sarcocystis neurona sporocysts after long-term storage

Veterinary Parasitology, 2004
The effect of long-term storage on the viability and infectivity of Sarcocystis neurona sporocysts was investigated. S. neurona sporocysts were harvested from the small intestine of Virginia opossums from 1996 to 2002 and stored at 4 degrees C. Viability of sporocysts was assessed by propidium iodide (PI) exclusion assay, in vitro excystation and ...
Hany M, Elsheikha, Alice J, Murphy, Linda S, Mansfield   +2 more
openaire   +2 more sources

Clinical Sarcocystis neurona, Sarcocystis canis, Toxoplasma gondii, and Neospora caninum infections in dogs

Veterinary Parasitology, 2006
Sarcocystis neurona, Sarcocystis canis, Toxoplasma gondii, and Neospora caninum are related apicomplexans that can cause systemic illness in many species of animals, including dogs. We investigated one breeder's 25 Basset Hounds for these infections. In addition, tissues from dogs and other non-canine hosts previously reported as S.
J P, Dubey, Jennifer L, Chapman, Benjamin M, Rosenthal, M, Mense, Ronald L, Schueler   +4 more
openaire   +2 more sources

Gray fox (Urocyon cinereoargenteus) identified as a new intermediate host for Sarcocystis neurona.

Veterinary Parasitology: Regional Studies and Reports
The protozoan Sarcocystis neurona can cause severe disease in horses, marine mammals, and several other animal species in North America. The Virginia opossum (Didelphis virginiana) is its definitive host, and the raccoon (Procyon lotor) has been ...
J. Dubey, Aditya Gupta, R. Calero-Bernal, L. S. de Araujo, M. L. García-Gil, J. Battle, Ankrah Ankarah, K. Van Why, Justin D. Brown, B. Rosenthal   +9 more
semanticscholar   +1 more source

Molecular genetic transfection of the coccidian parasite Sarcocystis neurona

Molecular and Biochemical Parasitology, 2006
Sarcocystis neurona is an apicomplexan parasite that is the major cause of equine protozoal myeloencephalitis (EPM). The biology of this pathogen remains poorly understood in part due to unavailability of molecular genetic tools. Hence, with an objective to develop DNA transfection capabilities for S.
Rajshekhar Y, Gaji, Deqing, Zhang, Cormac C, Breathnach, Shipra, Vaishnava, Boris, Striepen, Daniel K, Howe   +5 more
openaire   +2 more sources

Efficacy of decoquinate against Sarcocystis neurona in cell cultures

Veterinary Parasitology, 2013
Decoquinate is a quinolone anticoccidial approved for use in the prevention of intestinal coccidiosis in farm animals. This compound has good activity against Toxoplasma gondii and Neospora caninum in cell cultures. The drug acts on the parasites' mitochondria.
David S, Lindsay, M Mudasser, Nazir, Azhar, Maqbool, Siobhan P, Ellison, Jeannine S, Strobl   +4 more
openaire   +2 more sources

A fresh look at the SarcoFluor antibody test for the detection of specific antibodies to Sarcocystis neurona for the diagnosis of equine protozoal myeloencephalitis.

Veterinary parasitology
Equine protozoal myeloencephalitis (EPM) is a challenging disease to diagnose in horses with neurological signs. To optimize contemporary diagnostic testing, including the use of serum:CSF antibody ratios, the SarcoFluor antibody test for Sarcocystis ...
P. Pandit, W.A. Smith, Carrie J. Finno, Monica Aleman, Patricia A. Conrad, A. Packham, Magdalena Plancarte, Kevin D. Woolard, Antoinette Marsh, N. Pusterla   +9 more
semanticscholar   +1 more source

Early Migration of Sarcocystis neurona in Ponies Fed Sporocysts

Journal of Parasitology, 2007
Sarcocystis neurona is the most important cause of equine protozoal myeloencephalitis (EPM), a neurologic disease of the horse. In the present work, the kinetics of S. neurona invasion is determined in the equine model. Six ponies were orally inoculated with 250 x 10(6) S.
E, Elitsur, A E, Marsh, S M, Reed, J P, Dubey, M J, Oglesbee, J E, Murphy, W J A, Saville   +6 more
openaire   +2 more sources