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Nature Reviews Disease Primers, 2019 Sarcoidosis is an inflammatory disorder of unknown cause that is characterized by granuloma formation in affected organs, most often in the lungs. Patients frequently suffer from cough, shortness of breath, chest pain and pronounced fatigue and are at risk of developing lung fibrosis or irreversible damage to other organs.
Grunewald, Johan +5 more
semanticscholar +7 more sources
Annals of Medicine, 2022 Sarcoidosis is a heterogeneous disease, which can affect virtually every body organ, even though lungs and intra thoracic lymph nodes are almost universally affected.
Claudio Tana +6 more
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Environmental Risk Factors for Sarcoidosis
Frontiers in Immunology, 2020 Sarcoidosis is a multisystem granulomatous disease that may affect any body organ. Sarcoidosis is associated with many environmental and occupational exposures. Because the exact immunopathogenesis of sarcoidosis is unknown, it is not known whether these
Marc A. Judson
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Cutis, 2022 A Pink, elevated, granulomatous, indurated plaques on the face, including the nasal alae, of a 52-year-old woman with a darker skin tone. B Orange and pink, elevated, granulomatous, indurated plaques on the face of a 55-year-old woman with a lighter skin tone.
Candrice R, Heath, Richard P, Usatine
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Orphanet Journal of Rare Diseases, 2007 AbstractSarcoidosis is a multisystemic disorder of unknown cause characterized by the formation of immune granulomas in involved organs. It is an ubiquitous disease with incidence (varying according to age, sex, race and geographic origin) estimated at around 16.5/100,000 in men and 19/100,000 in women.
Valeyre Dominique +3 more
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Clinics in Chest Medicine, 2015 We present a 28-year-old man with a one-year history of cutaneous lesions in old scars and tattoos with concomitant subcutaneous nodules and myopathy. A skin biopsy specimen showed cutaneous sarcoidosis. We discuss the multiple aspects of this case, which represent unique presentations of this systemic disease as well as review isomorphic and isotopic ...
Robert P, Baughman, Daniel A, Culver
+11 more sources
ERS clinical practice guidelines on treatment of sarcoidosis
European Respiratory Journal, 2021 Background The major reasons to treat sarcoidosis are to lower the morbidity and mortality risk or to improve quality of life (QoL). The indication for treatment varies depending on which manifestation is the cause of symptoms: lungs, heart, brain, skin ...
R. Baughman +22 more
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Immune mechanisms in fibrotic pulmonary sarcoidosis
European Respiratory Review, 2022 Sarcoidosis is an immune-mediated disorder. Its immunopathology has been steadily mapped out over the past few decades. Despite this, the underpinning mechanisms for progressive fibrotic sarcoidosis is an almost uncharted area.
Praveen Weeratunga +2 more
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Sarcoidosis: A Clinical Overview from Symptoms to Diagnosis
Cells, 2021 Sarcoidosis is a multi-system disease of unknown etiology characterized by the formation of granulomas in various organs. It affects people of all ethnic backgrounds and occurs at any time of life but is more frequent in African Americans and ...
P. Sève +10 more
semanticscholar +1 more source