Safety and efficacy of stereotactic body radiation therapy in the treatment of pulmonary metastases from high grade sarcoma. [PDF]
Introduction. Patients with high-grade sarcoma (HGS) frequently develop metastatic disease thus limiting their long-term survival. Lung metastases (LM) have historically been treated with surgical resection (metastasectomy).
Agazaryan, Nzhde +9 more
core +2 more sources
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma
Synovial sarcoma tumours contain a characteristic fusion protein, SS18-SSX, which drives disease development. Targeting oncogenic fusion proteins presents an attractive therapeutic opportunity.
Gerard L Brien +16 more
doaj +1 more source
Synovial Sarcoma of the Extremities: A Literature Review
Synovial sarcoma (SS) is a rare and highly malignant tumor and a type of soft tissue sarcoma (STS), for which survival has not improved significantly in recent years.
Cosmin Ioan Faur +10 more
doaj +1 more source
Biphasic synovial sarcoma in the cervical spine: Case report [PDF]
Synovial sarcoma is a rare malignant neoplasm of soft tissue that typically arising near large joints of the upper and lower extremities in young adult males. Only 3% of these neoplasms have been found to arise in the head and neck region.
Stephen M Foreman, Michael J Stahl
core +1 more source
Primary synovial sarcoma of the brain in a 35-year-old patient: A rare clinical experience
Synovial sarcoma is an aggressive soft-tissue sarcoma with a poor prognosis and has an origin of uncertain histology. It frequently presents as a localised disease, especially near large joints around the knee and thigh.
P Harika Bhavani +4 more
doaj +1 more source
FUS-CHOP promotes invasion in myxoid liposarcoma through a SRC/FAK/RHO/ROCK-dependent pathway [PDF]
Deregulated SRC/FAK signaling leads to enhanced migration and invasion in many types of tumors. In myxoid and round cell liposarcoma (MRCLS), an adipocytic tumor characterized by the expression of the fusion oncogene FUS-CHOP, SRC have been found as one ...
González, M. Victoria +3 more
core +2 more sources
Primary synovial sarcoma of the prostate: A case report and literature review
Synovial sarcoma arising from the prostate is extremely rare. Synovial sarcoma of the prostate is usually identified at a late stage and makes the treatment challenging.
Ali Emadi Torghabe +2 more
doaj +1 more source
Targeted antiangiogenic agents in combination with cytotoxic chemotherapy in preclinical and clinical studies in sarcoma. [PDF]
Sarcomas are a heterogeneous group of mesenchymal malignancies. In recent years, studies have demonstrated that inhibition of angiogenic pathways or disruption of established vasculature can attenuate the growth of sarcomas.
DuBois, Steven G +2 more
core +1 more source
Ten cases of synovial cell sarcoma are reported. The youngest patient was a 2'A years old boy with synovial cell sarcoma of the knee and the oldest one was a man with synovial cell sarcoma of the elbow.
M. Farzan
doaj +2 more sources
Bortezomib Augments Natural Killer Cell Targeting of Stem-Like Tumor Cells. [PDF]
Tumor cells harboring stem-like/cancer stem cell (CSC) properties have been identified and isolated from numerous hematological and solid malignancies.
Ames, Erik +8 more
core +1 more source

