Results 131 to 140 of about 516,933 (343)

Emerging Nanozyme Strategies for Precision Breast Cancer Treatment

open access: yesAdvanced Science, EarlyView.
Different types of nanozymes‐mediated chemotherapy, photothermal therapy, immunotherapy, and multiple combined therapies for the effective treatment of breast cancer. Abstract Breast cancer, the most common malignant tumor among women worldwide, poses a significant challenge to public health due to its high incidence and mortality rates.
Jian Zang   +6 more
wiley   +1 more source

MARCO+ Tumor‐Associated Macrophages Impede CD8+ T Cell Immunity to Facilitate Immunotherapy Resistance in Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
MARCO+ TAMs dominate restrained cytotoxicity of CD8+ CTLs and ICB resistance in RCC. Mechanically, MARCO impairs MHC‐I‐mediated neoantigen cross‐presentation via the SOCS1‐JAK1‐STAT1‐NLRC5 signaling cascade in TAMs. Targeted MARCO treatment boosts macrophage antigen cross‐presentation and empowers CD8+ T cells, thereby potentiating ICB efficacy ...
Jiayuan Chen   +14 more
wiley   +1 more source

Targeting the EphA2 pathway: could it be the way for bone sarcomas?

open access: yesCell Communication and Signaling
Bone sarcomas are malignant tumors of mesenchymal origin. Complete surgical resection is the cornerstone of multidisciplinary treatment. However, advanced, unresectable forms remain incurable.
Giorgia Giordano   +4 more
doaj   +1 more source

The role of free flap reconstruction after resection of extremity and trunk soft tissue sarcomas. Results of two referral centers in Argentina

open access: yesClinical Surgical Oncology
Introduction: For patients affected by extremity or trunk soft-tissue sarcomas (STS) large resections might be needed to achieve negative margins. This is a common scenario especially in locally advanced or recurrent tumors often within a pre-irradiated ...
Sergio D. Quildrian   +3 more
doaj   +1 more source

Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas.

open access: yesNew England Journal of Medicine, 1995
E. Cesarman   +4 more
semanticscholar   +1 more source

Tumor Auxiliary Prediction Strategy Based on Multiscale Feature Fusion in Medical Decision‐Making System

open access: yesAdvanced Intelligent Systems, EarlyView.
GA: MCFFS method architecture. Pathological images are processed by the multi‐level feature information fusion (MLFF) method and the multi‐scale feature map fusion strategy to achieve the recognition result of cell nuclei. The MLFF module contains convolution blocks, spatial self‐attention, and atrous spatial pyramid pooling.
Yingqing Lu   +3 more
wiley   +1 more source

Early initiation of fast‐track care for persons living with HIV initiating dolutegravir‐based regimens during a period of severe civil unrest in Port‐au‐Prince, Haiti: a pilot randomized trial

open access: yesJournal of the International AIDS Society
Introduction Differentiated service delivery (DSD) models have been widely implemented for patients in stable HIV care. However, DSD has rarely been offered to newly diagnosed patients.
Jean Bernard Marc   +18 more
doaj   +1 more source

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