Results 161 to 170 of about 556,852 (338)

Early initiation of fast‐track care for persons living with HIV initiating dolutegravir‐based regimens during a period of severe civil unrest in Port‐au‐Prince, Haiti: a pilot randomized trial

open access: yesJournal of the International AIDS Society
Introduction Differentiated service delivery (DSD) models have been widely implemented for patients in stable HIV care. However, DSD has rarely been offered to newly diagnosed patients.
Jean Bernard Marc   +18 more
doaj   +1 more source

Multiparametric Bioresorbable Sensor for Doxorubicin Detection via Molecularly Imprinted Synthetic Receptors

open access: yesAdvanced Science, EarlyView.
A biodegradable molecularly imprinted polymer porous silica sensor enables dual optical readout of doxorubicin via fluorescence and effective optical thickness shifts. The combined transduction mechanisms provide enhanced reliability and quantitative accuracy over clinically relevant concentrations, representing a step toward transient implantable ...
Martina Corsi   +11 more
wiley   +1 more source

Recent advances in sarcoma therapy: new agents, strategies and predictive biomarkers

open access: yesJournal of Hematology & Oncology
Soft tissue and bone sarcomas are a heterogenous group of uncommon mesenchymal tumors with high unmet needs for novel therapeutic and diagnostic strategies. Despite many challenges that persist, innovative therapeutics are emerging.
Minggui Pan   +4 more
doaj   +1 more source

Investigating Phase Separation in Genome Folding via Multiscale Computational Modeling

open access: yesAdvanced Science, EarlyView.
Phase separation is emerging as a multiscale organizing principle of genome folding across scales, from nucleosomes and transcriptional condensates to chromatin domains and nuclear compartments. By integrating physics‐based simulations with data‐driven inference, computational modeling now links molecular interactions to nuclear architecture and points
Jiahu Tang   +3 more
wiley   +1 more source

Prognostic Significance of Portal Vein Tumor Thrombus in Pancreatic Ductal Adenocarcinoma Treated With Chemoradiotherapy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim To examine the significance of portal vein tumor thrombus (PVTT) as a prognostic factor for patients with pancreatic ductal adenocarcinoma (PDAC) treated with chemoradiotherapy (CRT) followed by surgery. Methods The study retrospectively examined 313 patients with borderline resectable (BR) or locally advanced (LA) PDAC who underwent CRT ...
Aoi Hayasaki   +9 more
wiley   +1 more source

Chromosomal assignment of the human homologues of feline sarcoma virus and avian myeloblastosis virus onc genes.

open access: green, 1982
Riccardo Dalla‐Favera   +5 more
openalex   +2 more sources

Sarcoma [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1937
openaire   +2 more sources

Management Strategies for Disappearing Colorectal Liver Metastases After Systemic Chemotherapy: Long‐Term Outcomes and Preoperative Prediction of ‘True Complete Response’

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Determining whether to resect disappearing liver metastases (DLMs) after chemotherapy for colorectal liver metastases (CRLMs) remains challenging. Methods Patients who underwent hepatectomy after systemic chemotherapy for initially unresectable CRLMs were reviewed. True complete response (CR) was defined as either resected DLMs with
Taihei Soma   +9 more
wiley   +1 more source

Phototriggered Morphological and Compositional Change of UGGAA Repeat RNA Foci by Photoswitchable RNA‐Binding Ligand

open access: yesAngewandte Chemie, EarlyView.
We here developed a molecular tool for the optical control of UGGAA repeat RNA foci, a pathological hallmark of spinocerebellar ataxia type 31 (SCA31). The photoswitchable RNA‐binding ligand enabled reversible control of the RNA foci. UV irradiation induced the growth of the RNA foci, while subsequent visible light irradiation dissolved the structure ...
Yusuke Fujiwara   +2 more
wiley   +2 more sources

Primary sarcoma of the aorta associated with a vascular prosthesis: A case report [PDF]

open access: bronze, 1980
David S. Weinberg, Baltej S. Maini
openalex   +1 more source

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