Results 161 to 170 of about 556,852 (338)
Introduction Differentiated service delivery (DSD) models have been widely implemented for patients in stable HIV care. However, DSD has rarely been offered to newly diagnosed patients.
Jean Bernard Marc +18 more
doaj +1 more source
A biodegradable molecularly imprinted polymer porous silica sensor enables dual optical readout of doxorubicin via fluorescence and effective optical thickness shifts. The combined transduction mechanisms provide enhanced reliability and quantitative accuracy over clinically relevant concentrations, representing a step toward transient implantable ...
Martina Corsi +11 more
wiley +1 more source
Recent advances in sarcoma therapy: new agents, strategies and predictive biomarkers
Soft tissue and bone sarcomas are a heterogenous group of uncommon mesenchymal tumors with high unmet needs for novel therapeutic and diagnostic strategies. Despite many challenges that persist, innovative therapeutics are emerging.
Minggui Pan +4 more
doaj +1 more source
Investigating Phase Separation in Genome Folding via Multiscale Computational Modeling
Phase separation is emerging as a multiscale organizing principle of genome folding across scales, from nucleosomes and transcriptional condensates to chromatin domains and nuclear compartments. By integrating physics‐based simulations with data‐driven inference, computational modeling now links molecular interactions to nuclear architecture and points
Jiahu Tang +3 more
wiley +1 more source
ABSTRACT Aim To examine the significance of portal vein tumor thrombus (PVTT) as a prognostic factor for patients with pancreatic ductal adenocarcinoma (PDAC) treated with chemoradiotherapy (CRT) followed by surgery. Methods The study retrospectively examined 313 patients with borderline resectable (BR) or locally advanced (LA) PDAC who underwent CRT ...
Aoi Hayasaki +9 more
wiley +1 more source
ABSTRACT Background Determining whether to resect disappearing liver metastases (DLMs) after chemotherapy for colorectal liver metastases (CRLMs) remains challenging. Methods Patients who underwent hepatectomy after systemic chemotherapy for initially unresectable CRLMs were reviewed. True complete response (CR) was defined as either resected DLMs with
Taihei Soma +9 more
wiley +1 more source
We here developed a molecular tool for the optical control of UGGAA repeat RNA foci, a pathological hallmark of spinocerebellar ataxia type 31 (SCA31). The photoswitchable RNA‐binding ligand enabled reversible control of the RNA foci. UV irradiation induced the growth of the RNA foci, while subsequent visible light irradiation dissolved the structure ...
Yusuke Fujiwara +2 more
wiley +2 more sources
Primary sarcoma of the aorta associated with a vascular prosthesis: A case report [PDF]
David S. Weinberg, Baltej S. Maini
openalex +1 more source

