Results 111 to 120 of about 44,600 (230)

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

Cell Proliferation, Volume 59, Issue 8, August 2026.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik, Muhammad Dilawar, Junguang Liao, Jie Zheng, Qitao Qian, Ming Xu, Sisi Lin, Xiaobo Zhu, Qiuwei Ge, Limin Jin, Guiqian Chen   +10 more
wiley   +1 more source

Sarcoma de Kaposi del canal vertebral

Colombia Medica, 1979
Se reporta un caso de Sarcoma de Kapasi del Canal vertebral como causa infrecuente de síndorme de compresión medular. Se revisa la literatura encontrándose 4 casos de compresión del sistema nervioso central. Se hace alusión a la etiología, cuado clínico y tratamiento de la entidad.
Alberto Muñoz, Humberto Caiaffa
openaire   +1 more source

Absence of DNA viruses in ameloblastomas

European Journal of Oral Sciences, Volume 134, Issue 4, August 2026.
Abstract Ameloblastomas (ABs) are rare odontogenic benign tumors. Although studies of the molecular pathogenesis have revealed the presence of mutations and altered gene expression, the etiology is unresolved. Viruses cause 10%–15 % of cancers, but their potential role within benign tumors is less studied.
Maria K. Jauhiainen, Jetta Kelppe, Maria Söderlund‐Venermo, Antti A. Mäkitie, Saku T. Sinkkonen, Jaana Hagström   +5 more
wiley   +1 more source

Sarcoma de Kaposi primário do pênis Primary Kaposi's sarcoma of the penis

Anais Brasileiros de Dermatologia, 2009
Sarcoma de Kaposi é um tumor vascular que afeta a parede dos vasos linfáticos. Possui quatro formas: clássica, endêmica, iatrogênica e associada ao HIV. É uma doença sistêmica, maligna, multifatorial e de curso variável. A apresentação inicial no pênis é rara, e mais observada em pacientes HIV positivos. Em pacientes HIV negativos, os casos que ocorrem
Maira Mitsue Mukai, Talitha Chaves, Lucio Caldas, José Fillus Neto, Jesus Rodriguez Santamaría   +4 more
openaire   +1 more source

Exosome‐Mediated Delivery of PROTACs for Targeted Protein Degradation in Cancer, Neurodegenerative, Infectious, and Inflammatory Diseases

Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are heterobifunctional molecules that hijack the ubiquitin‐proteasome system to drive catalytic, sub‐stoichiometric degradation of disease‐associated proteins, offering a mechanistic advantage over occupancy‐driven inhibitors and access to ‘undruggable’ targets.
Sruti Bagchi Ghosh, Rumpa Banerjee, Hailah M. Almohaimeed, Amany I. Almars, Tahani Ahmad ALMatrafi, Fayez M. Saleh, Zuhair M. Mohammedsaleh, Kranti Kiran Reddy Ealla, Ajoy Kumer, Bikram Dhara   +9 more
wiley   +1 more source

OX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 8, Page 1318-1331, August 2026.
OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.
Aditya K. Gupta, Julia Steriopoulos, Vasiliki Economopoulos, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source

Life Course Malaria Exposure and SARS‐CoV‐2 Seroepidemiology in Ugandan Adolescents: A Longitudinal Study Nested in a Birth Cohort

Tropical Medicine &International Health, Volume 31, Issue 8, Page 1012-1027, August 2026.
ABSTRACT Background COVID‐19 has had major global health impacts, yet reported morbidity and mortality have been lower in Africa despite serological evidence of widespread infection. Malaria has been proposed as a potential modifier of susceptibility to and outcomes of SARS‐CoV‐2 infection.
Ludoviko Zirimenya, Doreen Nayebare, Claire Baine, Jacent Nassuuna, Milly Namutebi, Christopher Zziwa, Denis Nsubuga, Fred Kiwudhu, Florence Akello, Josephine Tumusiime, Gloria Oduru, Grace Kabami, Hellen Akurut, Rachel Nakyesige, Agnes Natukunda, Anne Wajja, Lawrence Lubyayi, Simon Kimuda, Gyaviira Nkurunungi, Jennifer Serwanga, Katie J. Doores, Emily L. Webb, Alison M. Elliott   +22 more
wiley   +1 more source

Sarcoma de Kaposi y trasplante renal

Medicentro, 2021
El sarcoma de Kaposi es una neoplasia maligna que afecta la piel y puedeextenderse a órganos internos. Una de sus cuatro formas clínicas se denominaiatrógena o asociada a terapias inmunosupresoras empleadas en pacientestrasplantados.
Rafael Enrique Cruz Abascal, Yordán Martín Pozo, Johamel Ramos Valdez   +2 more
doaj  

Lesiones eritematovioláceas de aparición aguda

Revista del Hospital Italiano de Buenos Aires
Las manifestaciones cutáneas asociadas al HIV afectan a la mayoría de los pacientes con esta infección en algún momento del curso de la enfermedad. Las dermatosis inflamatorias e infecciosas son un 15% más frecuentes que en la población general.
Maite Lisa Eliceche, Agustín Bollea Garlatti, Mariana Caviedes, Gabriela Scalia, Ricardo Galimberti   +4 more
doaj  

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source