Results 31 to 40 of about 5,619 (197)

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

ANÁLISE DOS FATORES ASSOCIADOS À MORTALIDADE EM UMA COORTE DE PACIENTES DIAGNOSTICADOS COM SARCOMA DE KAPOSI

Brazilian Journal of Infectious Diseases, 2023
Introdução: O sarcoma de Kaposi (SK) é uma das principais neoplasias malignas definidoras de aids e apresenta importante morbimortalidade, além de perda da qualidade de vida. Trata-se de uma doença associada ao herpes vírus tipo 8 (HHV8), cujo tratamento
Danilo Luiz Marques de Carvalho, Sidnei Rana Pimentel, Ivelise Giarolla, Cristiano Melo Gamba, Simone de Barros Tenore, Paulo Roberto Abrão Ferreira   +5 more
doaj  

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

SARCOMA DE KAPOSI DISSEMINADO EM PACIENTE IMUNOCOMPETENTE: RELATO DE CASO

Brazilian Journal of Infectious Diseases, 2023
Introdução: O sarcoma de Kaposi (SK) é uma neoplasia endotelial associada ao Herpesvírus Humano 8, que comumente, se restringe a lesões cutâneas e de mucosa oral.
Celso Alessandro de Andrade, Giovana Sapienza Muro, Kelly Ayumi Haradad, Matheus Ferreira Martins, Rodrigo Luiz Martins Pantoja   +4 more
doaj  

Sarcoma de Kaposi em Paciente Jovem Imunocompetente: uma Quinta Variante Epidemiológica?

Revista Brasileira de Cancerologia, 2019
Introdução: O sarcoma de Kaposi apresenta, classicamente, quatro tipos de variantes: clássico, endêmico, associado à imunossupressão (ou iatrogênico) e epidêmico (ou relacionado à Aids).
Fernando Augusto Batista Campos, Karen Bento Ribeiro, Cristina da Cunha Hueb Barata de Oliveira, Jane Monteiro de Godoy Bernardes, Marcus Aurelho de Lima   +4 more
doaj   +1 more source

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

Aggregate, EarlyView.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang, Hao Fu, Jiangtao Lin, Meng Zhao, Chuanrong Chen, Hongze Liao, Yourong Duan   +6 more
wiley   +1 more source

Kaposi's Sarcoma: clinical and pathological aspects in patients seen at the Hospital Universitário Cassiano Antônio Moraes - Vitória - Espírito Santo - Brazil Sarcoma de Kaposi: achados clínico-patológicos nos pacientes atendidos no Hospital Universitário Cassiano Antônio Moraes - Vitória - Espírito Santo - Brazil

Anais Brasileiros de Dermatologia, 2012
BACKGROUND: Kaposi's sarcoma is a neoplasm of endothelial origin that is divided into four distinct types according to the clinical characteristics and the affected population: Classic (in elder men of Jewish or Mediterranean origin); Epidemic (in ...
Ricardo Montibeler Tiussi, Antonio Luiz de Oliveira Caus, Lucia Martins Diniz, Elton Almeida Lucas   +3 more
doaj   +1 more source

Identification of ferroptosis‐related genes involved in chronic obstructive pulmonary disease based on bioinformatics analysis

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan, Jinghui Xie, Lu Zhang, Xiao Ma, Lichangtian Jiao, Jie Zhu   +5 more
wiley   +1 more source

Sarcoma de Kaposi ocular. Presentación de un caso.

Gaceta Médica Espirituana, 2012
Fundamento: el sarcoma de Kaposi es una enfermedad tumoral descrita por primera vez por el médico húngaro Morita Kaposi en 1872 y puede presentarse con marcada frecuencia en pacientes seropositivos como enfermedad marcadora de sida. Presentación de caso:
Axel López Valdés, Vivian María Couce Herrera, Erians Valdés Pérez, Roxana María Almanza Alarcón, Edelby Escobar Carmona   +4 more
doaj