Results 51 to 60 of about 5,619 (197)
El sarcoma de Kaposi ó reticuloendoteliosis angiógena, como también se conoce a esta entidad dermatológica, fue descrito por primera vez por Moritz Kaposi en 1872 y por un siglo fue una enfermedad rara de varones ancianos.
Liusy Caridad Arías Benitez+3 more
doaj
Plaque‐Like Dermatofibroma: A Case Report and a Review of the Literature With a Focus on Dermoscopy
ABSTRACT Plaque‐like dermatofibroma (PLDF) is a rare clinical variant of dermatofibroma (DF), characterised by flat, infiltrative lesions, often larger than 50 mm in diameter and located on the trunk or lower extremities. A 44‐year‐old male presented to our clinic with a 20 cm brownish plaque with peripheral satellite lesions on the right antecubital ...
Francesco Cavallo+7 more
wiley +1 more source
Sarcoma de Kaposi e síndrome da imunodeficiência adquirida
No início da década de 80, a síndrome da imunodeficiência adquirida foi reconhecida e descrita em homossexuais jovens, do sexo masculino, previamente saudáveis, acometidos por pneumopatia atípica causada por microorganismo oportunista, identificado como ...
Benedito A. L. Fonseca+2 more
doaj +1 more source
Mapping protein–protein interactions by mass spectrometry
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu+4 more
wiley +1 more source
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro+5 more
wiley +1 more source
Exploring the Hemoglobin T to R2 Path Using Gaussian Elastic Network Correlation Map Distance
ABSTRACT Proteins are dynamic and undergo conformational changes. These changes may affect the motions executed by different regions of the proteins and are reflected in the motion correlation map. A method to accurately measure these changes is presented and exemplified on a set of tetrameric Hemoglobin structures.
Yuval Valenci, Dror Tobi
wiley +1 more source
SARCOMA DE KAPOSI - REVISÃO CLÍNICO-PATOLÓGICA
Introdução: O Sarcoma de Kaposi (SK) é uma afecção sistémica, cuja natureza neoplásica ou reactiva é controversa, que parece ter como origem a célula endotelial linfática e tem como agente etiológico o vírus herpes humano tipo 8 (HHV8). Existem 4 subtipos clínicos: clássico, epidémico, endémico e iatrogénico.Objectivos, material e métodos: Revisão ...
Z. Calima+6 more
openaire +3 more sources
Zosteriform Primary Cutaneous Marginal Zone Lymphoma—A Case Report
ABSTRACT We report a case of zosteriform PCMZL presenting in a T3–T4 dermatomal distribution not previously described in the literature. Although the varicella zoster virus was not detected in this case, late diagnosis of the acute eruption of zoster or even preceding zoster ‘sine herpete’ cannot be excluded as antigenic triggers.
Natalie Teh+4 more
wiley +1 more source
Lymphangiectatic Kaposi's sarcoma in a patient with AIDS [PDF]
Kaposi's sarcoma is a malignant disease that originates in the lymphatic endothelium. It has a broad spectrum of clinical manifestations. Its four distinct clinical forms are: classic, endemic, iatrogenic and epidemic Kaposi's sarcoma. In non-HIV-associated Kaposi's sarcoma, the disease is typically limited to the lower extremities, but in ...
Santos, Mônica+4 more
openaire +5 more sources
A guide to heat shock factors as multifunctional transcriptional regulators
The heat shock factors (HSFs) are evolutionarily conserved transcription factors best known as regulators of molecular chaperone genes in response to heat shock and other protein‐damaging stresses. Vertebrate HSFs, HSF1‐5, HSFX, and HSFY, are implicated in various physiological and pathological processes, including organismal development and cancer ...
Hendrik S. E. Hästbacka+3 more
wiley +1 more source