Results 101 to 110 of about 146,949 (323)

Ultrasound Muscle Assessment and Nutritional Status in Institutionalized Older Adults: A Pilot Study [PDF]

, 2019
Muscle thickness, measured by ultrasonography, has been investigated for nutritional assessment in older adults, however the associations between muscle ultrasound parameters in the lower limb and nutritional status have not been studied.
Alejandro Galán-Mercant, Alvaro Mateos-Angulo, Antonio Ignacio Cuesta-Vargas, da Silva Soares, Fess, Ross   +5 more
core   +3 more sources

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK pathways

Arthritis &Rheumatology, Accepted Article.
Introduction Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source

Pharmacokinetics, pharmacodynamics and safety of vutiglabridin after multiple oral administrations in healthy female and obese subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims Vutiglabridin (HSG4112) is a novel drug under clinical development for antiobesity treatment. This study aimed to evaluate the pharmacokinetics (PKs) and safety of vutiglabridin after multiple oral administrations in healthy Korean female and obese subjects and explore short‐term pharmacodynamic (PD) responses.
Sooyoun Lee, Hyun Chul Kim, Young Ran Yoon, In‐Jin Jang, Sang‐Ku Yoo, Kyung‐Sang Yu   +5 more
wiley   +1 more source

Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-alpha2-deficient congenital muscular dystrophy (MDC1A) [PDF]

, 2012
BACKGROUND: Laminin-alpha2-deficient congenital muscular dystrophy (MDC1A) is a severe muscle-wasting disease for which no curative treatment is available.
Lin, Shuo, Meinen, Sarina, Ruegg, Markus A.   +2 more
core   +1 more source

Pharmacokinetics of dolutegravir, tenofovir and lamivudine during venous–venous extracorporeal membrane oxygenation (VV‐ECMO): A case report

British Journal of Clinical Pharmacology, EarlyView.
While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart, Emiel Leegwater, Thomas H. Ottens, Emile F. Schippers, Erik B. Wilms, David M. Burger, Cees van Nieuwkoop, Liesbeth B. E. Bosma   +7 more
wiley   +1 more source

Association of Characteristics between Acute Stroke Patients and Sarcopenia: A Cross-Sectional Study [PDF]

운동과학
PURPOSE This study aimed to identify the prevalence of sarcopenia among acute stroke patients, differences in characteristics based on the presence of sarcopenia, the association between functional and sarcopenia factors, and the association between ...
So-Yeong Kim, Byeong-Geun Kim, Se-Ju Park   +2 more
doaj   +1 more source

Ammonia toxicity: from head to toe? [PDF]

, 2016
Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues.
Dasarathy, Srinivasan, Mookerjee, Rajeshwar P., Ott, Peter, Rackayova, Veronika, Rangroo Thrane, Vinita, Rose, Christopher, Vairappan, Balasubramaniyan   +6 more
core   +1 more source

Prevalence of sarcopenia under different diagnostic criteria and the changes in muscle mass, muscle strength, and physical function with age in Chinese old adults

, 2022
Mengyu Cao, Junsong Lian, Xisheng Lin, Jinwei Liu, Chao Chen, Shuaixuan Xu, Shuang Ma, Fang Wang, Nihui Zhang, Xiaolei Qi, Xu Guogang, Nan Peng   +11 more
openalex   +1 more source

Communications to the International Sarcopenia Translational Research Conference 2023 [PDF]

, 2023
Avan Sayer, Lesley Anderson, Gayle Cain, Daniela Carpinelli, Rachel Cooper, Antoneta Granic, Christopher Hurst, Eleanor Lockhart, Amie O'halloran, Sian Robinson, Karen Suetterlin, Miles Witham, Senescence-, Daisy Wilson, Andrew Clegg, Lesley Brown, Thomas Jackson, Istrc 2023, Rafaela Cavalheiro, Esprito Santo, Daniel Nbrega De Moraes, Lucas Dria, Leonardo Peterson, Santos, Vanessa Hax, Tayane Fighera, Mara Poli, Spritzer, Ricardo Machado, S Tan, Roope Mannikko, Emma Matthews, Linda Greensmith, Michael Hanna, Efspraxia Kritikaki, Gerassimos Terzis, Ioannis Vogiatzis, Davina Simoes, Joshua Bennett, Kieren Hollingsworth, Arthur Pratt, Maha Egail, Catherine Feeney, Valeria Leo, Robert Taylor, Richard Dodds, Amy Anderson, John Isaacs, Julie Pasco, Michael Berk, Brenda Penninx, Natalie Hyde, Kara Holloway-Kew, Emma West, Mark Kotowicz, Kara Anderson, Adrienne O'neil, Pamela Rufus-Membere, Lana Williams   +58 more
openalex   +1 more source

Cystatin C‐based eGFR better predicts renal vancomycin clearance than creatinine‐based eGFR in patients with allogeneic stem cell transplantation

Clinical Pharmacology &Therapeutics, EarlyView.
Knowledge of the glomerular filtration rate (GFR) is mandatory when dosing renally eliminated drugs such as vancomycin. In clinical practice, different biomarkers and various equations are used to estimate GFR (eGFR), resulting in varying estimates.
Eva‐Maria A. Wansing, Sebastian G. Wicha, Peter Bannas, Alexander Heitkamp, Adrin Dadkhah, Nicolaus M. Kröger, Isabel Molwitz, Claudia Langebrake   +7 more
wiley   +1 more source