Results 111 to 120 of about 169,719 (379)

Sarcopenia: A Contemporary Health Problem among Older Adult Populations

Nutrients, 2020
Sarcopenia, a geriatric disease characterized by a progressive loss of skeletal muscle mass and loss of muscle function, constitutes a rising, often undiagnosed health problem.
S. Papadopoulou
semanticscholar   +1 more source

Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Organs Aging by Regulating the Sik1 Pathway Through Maintaining Calcium Homeostasis

Advanced Science, EarlyView.
Aging involves physiological decline and heightened disease susceptibility, necessitating effective interventions. Redox‐responsive selenium‐loaded nanoparticles (SeMSNs) are developed, which delay cellular senescence by reducing oxidative stress and senescence markers (p16/p21). In aged mice, SeMSNs extend lifespan, improve organ function, and restore
Yang Yu, Jintao Song, Mengjiao Guo, RuZe Ma, Mingyang Du, Zhe Xun, Xu Liu, RongXia Xu, Xiaochun Xie, Peilin Qi, Yujie Chen, Dan Shao, Chao Yang, Liang Wang, Xiaoyu Song, Difei Wang   +15 more
wiley   +1 more source

The FNIH Sarcopenia Project: Rationale, Study Description, Conference Recommendations, and Final Estimates

The journals of gerontology. Series A, Biological sciences and medical sciences, 2014
Background. Low muscle mass and weakness are common and potentially disabling in older adults, but in order to become recognized as a clinical condition, criteria for diagnosis should be based on clinically relevant thresholds and independently validated.
S. Studenski, K. Peters, D. Alley, P. Cawthon, R. McLean, T. Harris, L. Ferrucci, J. Guralnik, Maren S Fragala, A. Kenny, D. Kiel, S. Kritchevsky, M. Shardell, Thuy-Tien L. Dam, M. Vassileva   +14 more
semanticscholar   +1 more source

Drug‐related sarcopenia as a secondary sarcopenia

Geriatrics & Gerontology International, 2023
Sarcopenia has a significant impact on falls, physical function, activities of daily living, and quality of life in older adults, and its prevention and treatment are becoming increasingly important as the global population ages. In addition to primary age‐related sarcopenia, activity‐related sarcopenia, disease‐related sarcopenia, and nutrition ...
openaire   +2 more sources

Prolonged Cell Encapsulation and Gravity‐independent Filamented Light Biofabrication of Muscle Constructs

Advanced Science, EarlyView.
A gravity‐independent filamented light (G‐FLight) projection method is presented for rapid biofabrication of anisotropic tissues, demonstrated with muscle constructs as a target application. Specialized photocrosslinkable resins enable refrigeration or cryopreservation with encapsulated cells.
Michael Winkelbauer, Jakub Janiak, Johannes Windisch, Hao Liu, Maria Bulatova, Max Von Witzleben, Hugo Oliveira, Sophie Dani, Richard Frank Richter, Nicolas L’Heureux, Ori Bar‐Nur, Michael Gelinsky, Marcy Zenobi‐Wong, Parth Chansoria   +13 more
wiley   +1 more source

Living in interesting times - Challenging protein metabolism in the era of the epidemiological shift [PDF]

, 2016
The recently released results of the Global Burden of Disease, Injuries, and Risk Factor study 2013 reveal that during the past 23 years, metabolic and behavioral risk factors, including high BMI, increased their impact on global mortality and disability-
Laviano, Alessandro
core   +1 more source

Sarcopenia and catastrophic health expenditure by socio‐economic groups in China: an analysis of household‐based panel data

Journal of Cachexia, Sarcopenia and Muscle, 2022
Background Sarcopenia was thought to be associated with adverse outcomes and will cause lots of health expenditure. But the relationship between sarcopenia and catastrophic health expenditure (CHE) had been little explored.
Chen Ye, Xu Zheng, Sumiya Aihemaitijiang, Ruoyu Wang, Mairepaiti Halimulati, Xiaojie Huang, Zhaofeng Zhang   +6 more
doaj   +1 more source

Lactobacillus Salivarius‐Derived Indole‐3‐Acetic Acid Promotes AHR‐PARP1 Axis‐Mediated DNA Repair to Mitigate Intestinal Aging

Advanced Science, EarlyView.
Indole‐3‐acetic acid (IAA) acting as one of the aryl hydrocarbon receptor (AHR) endogenous ligands is identified to be derived from Lactobacillus salivarius via its catalytic enzyme (ALDH) rather than host cells. Lactobacillus salivarius and IAA supplementation effectively mitigate intestinal aging by facilitating AHR‐poly (ADP‐ribose) polymerase 1 ...
Zheng Cao, Cui Zhang, Hehua Lei, Weichuan Lin, Wenkai Yu, Xin Gao, Yanmeng He, Xinzhi Li, Qingwei Xiang, Zhiwen Zhang, Weifei Luo, Andrew D. Patterson, Limin Zhang, Gang Chen   +13 more
wiley   +1 more source

Body composition, IGF1 status, and physical functionality in nonagenarians: implications for osteosarcopenia [PDF]

, 2018
OBJECTIVES: Body composition alterations occur during aging. The purpose of the present analysis was to explore the functional consequences of the overlap of sarcopenia and osteoporosis, and the potential role of insulin-like growth factor 1 (IGF1) in ...
Cherry, Ke, Jazwinski, Sm, Kim, S, Myers, L, Poggiogalle, E, Ravussin, E., Su, Lj, Welsh, Da   +7 more
core  

Determinants of dementia risk among older adults with probable sarcopenia and sarcopenia

BMC Public Health
Background Probable sarcopenia is a condition related to low muscle strength which increases the risk of sarcopenia. Both probable sarcopenia and sarcopenia increases the risk of dementia.
Nur Indrawaty Lipoeto, Divya Vanoh, Desmawati Desmawati, Wan Rosli Wan Ishak, Rosminah Mohamed   +4 more
doaj   +1 more source