Results 1 to 10 of about 805,395 (207)

SARS-CoV-2 entry into and evolution within a skilled nursing facility

Scientific Reports, 2023
AbstractSARS-CoV-2 belongs to the family Coronaviridae which includes multiple human pathogens that have an outsized impact on aging populations. As a novel human pathogen, SARS-CoV-2 is undergoing continuous adaptation to this new host species and there is evidence of this throughout the scientific and public literature.
Sexton, Nicole R., Cline, Parker Parker, Gallichotte, Emily N., Fitzmeyer, Emily, Young, Michael C., Janich, Ashley J., Pabilonia, Kristy L., Ehrhart, Nicole, Ebel, Gregory D.   +8 more
openaire   +3 more sources

False‐positive reverse transcriptase polymerase chain reaction screening for SARS‐CoV‐2 in the setting of urgent head and neck surgery and otolaryngologic emergencies during the pandemic: Clinical implications [PDF]

Head & Neck, 2020
AbstractBackgroundNo reports describe falsepositive reverse transcriptase polymerase chain reaction (RT‐PCR) for novel coronavirus in preoperative screening.MethodsPreoperative patients had one or two nasopharyngeal swabs, depending on low or high risk of viral transmission. Positive tests were repeated.ResultsForty‐three of 52 patients required two or
Katz, Andrew P., Civantos, Francisco J., Sargi, Zoukaa, Leibowitz, Jason M., Nicolli, Elizabeth A., Weed, Donald, Moskovitz, Alexander E., Civantos, Alyssa M., Andrews, David M., Martinez, Octavio, Thomas, Giovana R.   +10 more
openaire   +4 more sources

Knowledge and awareness of dental specialists, general dentists and dental assistants regarding SARS‑CoV‑2

Dental and Medical Problems, 2021
خلفية: كان لفيروس كورونا 2 المرتبط بالمتلازمة التنفسية الحادة الوخيمة (سارس- كوف-2) آثار جذرية بين أخصائيي الرعاية الصحية. الأهداف. تهدف هذه الدراسة إلى تقييم المعرفة والوعي بين أخصائيي الأسنان وأطباء الأسنان العامين ومساعدي الأسنان فيما يتعلق بالإرشادات القياسية لرعاية المرضى لتقليل انتشار العدوى. المواد والطرق. أجريت دراسة مستعرضة قائمة على المسح على
Hafsa Qabool, Rashna Hoshang Sukhia, Mubassar Fida   +2 more
openaire   +2 more sources

AmpliCoV: Rapid Whole-Genome Sequencing Using Multiplex PCR Amplification and Real-Time Oxford Nanopore MinION Sequencing Enables Rapid Variant Identification of SARS-CoV-2

Frontiers in Microbiology, 2021
Since the emergence of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) in December 2019, the scientific community has been sharing data on epidemiology, diagnostic methods, and whole-genomic sequences almost in real time. The latter have
Annika Brinkmann, Sophie-Luisa Ulm, Steven Uddin, Sophie Förster, Dominique Seifert, Rainer Oehme, Merle Corty, Lars Schaade, Janine Michel, Andreas Nitsche   +9 more
doaj   +1 more source

In Silico Identification of Potential Inhibitors of the SARS-CoV-2 Nucleocapsid Through Molecular Docking-Based Drug Repurposing

Dr. Sulaiman Al Habib Medical Journal, 2022
AbstractSARS-CoV-2 is the virus responsible for the COVID-19 pandemic, and its effects on people worldwide continue to grow. Protein-targeted therapeutics are currently unavailable for this virus. As with other coronaviruses, the nucleocapsid (N) protein is the most conserved RNA-binding structural protein of SARS-CoV-2.
Rukhsar Afreen, Saleem Iqbal, Ab Rauf Shah, Heena Afreen, Lata Vodwal, Mohd. Shkir   +5 more
openaire   +2 more sources

SARS-CoV-2 in silico binding affinity to human leukocyte antigen (HLA) Class II molecules predicts vaccine effectiveness across variants of concern (VOC)

Scientific Reports, 2022
There is widespread concern about the clinical effectiveness of current vaccines in preventing Covid-19 caused by SARS-CoV-2 Variants of Concern (Williams in Lancet Respir Med 29:333–335, 2021; Hayawi in Vaccines 9:1305, 2021), including those identified
Spyros A. Charonis, Lisa M. James, Apostolos P. Georgopoulos   +2 more
doaj   +1 more source

Evaluation of a commercial ELISA as alternative to plaque reduction neutralization test to detect neutralizing antibodies against SARS-CoV-2

Scientific Reports, 2022
High-throughput detection of neutralizing antibodies against SARS-CoV-2 presents a valuable tool for vaccine trials or investigations of population immunity.
Natalie Hofmann, Marica Grossegesse, Markus Neumann, Lars Schaade, Andreas Nitsche   +4 more
doaj   +1 more source

Longitudinal SARS-CoV-2 seroepidemiological investigation among healthcare workers at a tertiary care hospital in Germany

BMC Infectious Diseases, 2022
Background SARS-CoV-2 cases in Germany increased in early March 2020. By April 2020, cases among health care workers (HCW) were detected across departments at a tertiary care hospital in Berlin, prompting a longitudinal investigation to assess HCW SARS ...
Sara Tomczyk, Alexander Hönning, Julia Hermes, Marica Grossegesse, Natalie Hofmann, Janine Michel, Markus Neumann, Andreas Nitsche, Berthold Hoppe, Tim Eckmanns, Hajo Schmidt-Traub, Kristina Zappel   +11 more
doaj   +1 more source

Flexible upscaling of laboratory PCR testing capacity at the Robert Koch Institute during the SARS-CoV-2 pandemic

Virology Journal, 2023
Background Over the course of the COVID-19 pandemic, laboratories worldwide have been facing an unprecedented increase in demand for PCR testing because of the high importance of diagnostics for prevention and control of virus spread.
Eva Krause, Janine Michel, Andreas Puyskens, Natalie Hofmann, Thomas Rinner, Barbara Biere, Brigitte G. Dorner, Martin Skiba, Lars Schaade, Andreas Nitsche   +9 more
doaj   +1 more source

Using primary literature on SARS‐CoV‐2 to promote student learning about evolution [PDF]

Ecology and Evolution, 2020
AbstractThe ongoing COVID‐19 pandemic caused by SARS‐CoV‐2 has caused widespread deaths, illnesses, and societal disruption. I describe here how I pivoted a discussion‐based senior biology capstone course to include a multiweek module surrounding one primary literature paper on the evolution of SARS‐CoV‐2 and the subsequent scientific discourse about ...
openaire   +5 more sources