Results 151 to 160 of about 1,242,031 (332)

Pathogenicity of SARS‐CoV‐2 Omicron

Clinical and Translational Medicine, 2022
Hin Chu, Kwok‐Yung Yuen
doaj   +1 more source

Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis

Advanced Science, EarlyView.
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao, Ruiyan Ma, Shuai Hao, Xuxin Tan, Xue Zeng, Rui Song, Bing Chen, Zhezhe Cao, Wei Shen, Zhenchun Luo, Jianfeng Huang, He Huang, Liangming Liu, Chenyang Duan   +13 more
wiley   +1 more source

Endocrine significance of SARS-CoV-2’s Reliance on ACE2 [PDF]

, 2020
Mark C. Chappell
openalex   +1 more source

D‐glucuronyl C5‐Epimerase Binds to EGFR to Suppress Kidney Fibrosis

Advanced Science, EarlyView.
Glucuronyl C5‐epimerase (Hsepi, gene name Glce) is a key enzyme catalyzing heparan sulfate (HS) chain biosynthesis in HS proteoglycans, which are ubiquitously expressed on cell membranes. In normal renal tubular cells, Glce binds to the intracellular domains of EGFR, maintaining stable and orderly EGFR phosphorylation.
Xiaoqi Jing, Jun Wu, Jingru Ning, Xiaoyu Ding, Zhenyun Du, Xiaojiang Wang, Lulin Huang, Ran Wang, Changlin Mei, Kan Ding   +9 more
wiley   +1 more source

Intrafamilial Exposure to SARS-CoV-2 Induces Cellular Immune Response without Seroconversion

, 2020
Floriane Gallais, Aurélie Velay, Marie-Josée Wendling, Charlotte Nazon, Marialuisa Partisani, Jean Sibilia, Sophie Candon, Samira Fafi‐Kremer   +7 more
openalex   +1 more source

A Near‐Field Coupling Array Enables Parallel Imaging and SNR Gain in MRI

Advanced Science, EarlyView.
This paper proposes a metasurface‐based radiofrequency (RF) coil architecture, providing a universal theoretical framework for the application of decoupled metasurface arrays in magnetic resonance imaging, with potential to address wireless connectivity issues in magnetic resonance imaging RF coils.
Zhiguang Mo, Shao Che, Feng Du, Enhua Xiao, Qiaoyan Chen, Nan Li, Sen Jia, Changjun Tie, Bing Wu, Xiaoliang Zhang, Hairong Zheng, Ye Li   +11 more
wiley   +1 more source

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

Cell, 2020
A. Walls, Young-Jun Park, M. Alexandra Tortorici, A. Wall, Andrew T. McGuire, D. Veesler   +5 more
semanticscholar   +1 more source

PIM1 Attenuates Innate Immunity to Foster Coronavirus Replication through Ubiquitin Ligase β‐TrCP‐Mediated IFNAR1 Degradation

Advanced Science, EarlyView.
Hijacking Host Kinase PIM1: A β‐Coronavirus (OC43) strategy to degrade IFNAR1 and evade antiviral immunity. Human β‐coronaviruses (OC43) exploit the proto‐oncoprotein PIM1 kinase to sabotage innate immunity. Viral RNA/proteins upregulate PIM1, which phosphorylates E3 ligase β‐TrCP1.
Qianya Wan, Lin Zhu, Cien Chen, Li Zhong, Houying Leung, Wei Li, Chang Xu, Xi Yao, Huan Hu, Mandi Wu, Yuxin Hou, Hin Chu, Yiran Wang, Sheng Chen, Mingyu Pan, Zongwei Cai, Ming‐liang He   +16 more
wiley   +1 more source

SARS‐CoV‐2 infection in lung transplant recipients induces circulating exosomes with SARS‐CoV‐2 spike protein S2

Clinical and Translational Medicine, 2021
Sandhya Bansal, Sofya Tokman, Timothy Fleming, Gabriel N. Maine, Kristina Sanborn, Ramsey Hachem, Ankit Bharat, Michael A. Smith, Ross M. Bremner, T. Mohanakumar   +9 more
doaj   +1 more source

Infection fatality risk for SARS-CoV-2: a nationwide seroepidemiological study in the non-institutionalized population of Spain

, 2020
Roberto Pastor‐Barriuso, Beatriz Pérez‐Gómez, Miguel A. Hernán, Mayte Pérez‐Olmeda, Raquel Yotti, Jesús Calatayud, Jose L Sanmartín, Inmaculada León-Gómez, Aurora Fernández-García, Pablo Fernández‐Navarro, Israel Cruz, Mariano Martín, Concepción Delgado‐Sanz, Nerea Fernández‐de‐Larrea, José León Paniagua, Juan F Muñoz-Montalvo, Faustino Blanco, Amparo Larrauri, Marina Pollán   +18 more
openalex   +1 more source