Results 221 to 230 of about 18,157,587 (245)

Personalized Treatment of Patients With Multiple Sclerosis: A Case Report and Literature Review

Medicine Bulletin, EarlyView.
ABSTRACT Managing multiple sclerosis (MS) with a highly active disease course presents significant challenges, particularly regarding the timing of therapeutic escalation and the preservation of brain volume. We present a personalized management strategy for a 36‐year‐old male with relapsing‐remitting MS (RRMS) who experienced initial misdiagnosis ...
Fengjun Wang, Han Wang, Yu Zhang, Guoxun Zhang   +3 more
wiley   +1 more source

SARS‐CoV‐2 enhances lysosomal exocytosis and deacidifies lysosomes to facilitate viral release

mLife, EarlyView.
Abstract The mechanism of SARS‐CoV‐2 egress predominantly governs the quantity and quality of progeny viruses, thereby significantly contributing to viral pathogenicity. However, the key factors influencing viral egress remain largely unclear. In this study, using transcription‐ and replication‐competent SARS‐CoV‐2 virus‐like‐particle (SARS‐CoV‐2 trVLP)
Fujun Qin, Chuang Yan, Zizheng Liu, Dianbing Wang, Huimin Zhong, Qiang Ding, Minghai Chen, Xian‐En Zhang   +7 more
wiley   +1 more source

Unveiling the Structural and Mechanical Diversity of SARS-CoV-2 Variants Using Atomic Force Microscopy. [PDF]

ACS Appl Mater Interfaces
Sziklai D, Budavári B, Kiss B, Herényi L, Kis Z, Pályi B, Kellermayer M.   +6 more
europepmc   +1 more source

Cefdinir reprograms Gram‐positive bacteria to synergize with lysozyme against superbugs

mLife, EarlyView.
Abstract Multidrug‐resistant (MDR) bacteria pose a critical global health threat, urgently requiring solutions. Cefdinir, the highest‐selling third‐generation cephalosporin but one now facing clinical obsolescence due to escalating resistance, is conventionally classified as a nascent cell wall synthesis inhibitor.
Qi Zhang, Yang Yang, Shuqi Li, Zhao Liu, Chun‐Kit Lee, Chi‐Bun Ko, Qian Zhao   +6 more
wiley   +1 more source

Wastewater Surveillance for SARS-CoV-2 in Rural Kentucky, 2021-2023. [PDF]

Viruses
Keck JW, Adatorwovor R, Noble A, Tucker S, Strike WD, Torabi S, Banadaki MD, Mijatovic B, Roggenkamp SK, McNeil DL, Ormsbee LE, Berry SM.   +11 more
europepmc   +1 more source

On the analyzing of bifurcation properties of the one‐dimensional Mackey–Glass model by using a generalized approach

Mathematical Methods in the Applied Sciences, EarlyView.
The goal of this work is to look at how a nonlinear model describes hematopoiesis and its complexities utilizing commonly used techniques with historical and material links. Based on time delay, the Mackey–Glass model is explored in two instances. To offer a range, the relevance of the parameter impacting stability (bifurcation) is recorded.
Shuai Zhang, Yaya Wang, Hongyin Geng, Wei Gao, Esin Ilhan, Haci Mehmet Baskonus   +5 more
wiley   +1 more source

A Case of Sudden Unexpected Infant Death with Presumptive SARS-CoV-2 Infection. [PDF]

Int J Mol Sci
Galichina VA, Nasyrov RA, Davydova ZV, Gabaraev SE, Yagmurov OD.   +4 more
europepmc   +1 more source

Simultaneous T2, T2*, and R2′ Mapping for Multiple Sclerosis Using Nonlinear Model‐Based Reconstruction of Undersampled Radial RARE‐EPI MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To demonstrate the synergy of undersampled radial 2in1‐RARE‐EPI acquisition and nonlinear model‐based reconstruction for accelerated and simultaneous T2, T2*, and R2′ mapping in brains of patients with multiple sclerosis (MS). Methods 2in1‐RARE‐EPI combines a RARE module with an EPI module to capture T2 and T2* information.
Jose Raul Velasquez Vides, Carl J. J. Herrmann, Thomas Gladytz, Hoby P. Hetherington, Hendrik Mattern, Xiaoqing Wang, Jason M. Millward, Shahriar Shalikar, Igor Fabian Tellez Ceja, Beate Endemann, Sonia Waiczies, Joseph Kuchling, Friedemann Paul, Georg Rose, Min‐Chi Ku, Franz Schmitt, Thoralf Niendorf   +16 more
wiley   +1 more source

Recent COVID-19 Vaccination and Risk of SARS-CoV-2 Transmission.

JAMA Netw Open
Benist SC, Smith-Jeffcoat SE, Talbot HK, Zhu Y, Schmitz JE, Scott TA, Stockwell MS, McLaren SH, Sano ED, Vargas CY, Valdez de Romero A, Chu HY, Englund JA, Clark E, MacMillan MP, Lauring AS, Oyegun EI, Bertumen JB, Grijalva CG, Kirking HL.   +19 more
europepmc   +1 more source