Results 251 to 260 of about 1,274,904 (321)

Resistance of endothelial cells to SARS-CoV-2 infection <i>in vitro</i>. [PDF]

open access: yesJ Virol
Ahmetaj-Shala B   +7 more
europepmc   +1 more source

Membralin Assembles a MAN1B1–VCP Complex to Target Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation

open access: yesAdvanced Science, EarlyView.
This study identifies Membralin as an ER‐phagy receptor that recruits MAN1B1 and VCP to form a selective ERLAD complex. By sensing dense N‐glycan clusters on viral fusion glycoproteins, this ubiquitin‐independent pathway directs SARS‐CoV‐2 spike, Ebola GP, influenza HA, and HIV‐1 Env to lysosomal degradation, thereby limiting viral infectivity ...
Jing Zhang   +5 more
wiley   +1 more source

Rethinking Power Solutions for Healthcare Wearables: From Point‐of‐Care and Episodic use to Continuous Monitoring and Therapeutic Platforms

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
This Perspective examines practical power solutions for wearable healthcare systems, highlighting the limits of standard batteries. It categorizes wearables into four domains—point‐of‐care diagnostics, episodic monitoring, continuous long‐term monitoring, and therapeutic platforms—and analyzes their power needs.
Seokheun Choi
wiley   +1 more source

The Common Cold Is Associated With Protection From SARS-CoV-2 Infections. [PDF]

open access: yesJ Infect Dis
Moore CM   +40 more
europepmc   +1 more source

Analysis of B Cell Receptor Repertoires Reveals Key Signatures of the Systemic B Cell Response after SARS-CoV-2 Infection

open access: hybrid, 2021
Yudi Zhang   +20 more
openalex   +1 more source

Transcranial Direct Current Stimulation Neuromodulation in Elderly Individuals and Its Impact on Anxiety and Depression Symptoms

open access: yesAGING MEDICINE, EarlyView.
Anodal tDCS over the left prefrontal cortex, combined with cognitive training, enhanced cognition, reduced anxiety and depression, and improved motor response in elderly women. These findings support tDCS as a safe, effective strategy for promoting brain plasticity and mental health in aging.
Guilherme Augusto Santos Bueno   +5 more
wiley   +1 more source

Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2

open access: yesCell, 2020
Qihui Wang   +13 more
semanticscholar   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

open access: yesAdvanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng   +4 more
wiley   +1 more source

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