Results 271 to 280 of about 1,293,835 (325)

The evolutionary landscape and serotypic dynamics of avian infectious bronchitis virus from spike protein

iMetaOmics, EarlyView.
This study integrates two decades of surveillance with genomic and structural analyses to decipher how spike protein glycosylation haplotypes drive avian coronavirus evolution. We uncover how specific glycosylation patterns associate with receptor‐binding affinity, shape global transmission dynamics, and correlate with clinical outcomes.
Hao Zhang, Zongxi Han, Chuangchao Zou, Yihui Huang, Shiping Sun, Ouyang Peng, Usama Ashraf, Qiuping Xu, Yao Ge, Qixiang Kang, Xiuli Ma, Xinheng Zhang, Ye Zhao, Xin Yang, Hongning Wang, Guozhong Zhang, Qingmei Xie, Mang Shi, Yongsen Ruan, Min Liao, Shengwang Liu, Yongchang Cao   +21 more
wiley   +1 more source

High-Fidelity and Cost-Effective Engineering of SARS-CoV-2. [PDF]

Viruses
Olguin-Nava M, Hennig T, Börtlein C, Bohn P, Ambi UB, Gabel A, Günter LM, Gribling-Burrer AS, Schmidt N, Caliskan N, Dölken L, Munschauer M, Smyth RP.   +12 more
europepmc   +1 more source

Diagnostic Concordance of Two‐ and Three‐Gene SARS‐CoV‐2 Molecular Assays in Cameroon: Implications for Efficient Pandemic Response in Low‐ and Middle‐Income Countries

Journal of Clinical Laboratory Analysis, EarlyView.
This study assessed the interoperability of DaAn Gene, ThermoFisher, and GeneXpert assays used for COVID‐19 testing in Cameroon. GeneXpert showed higher diagnostic performance over ThermoFisher, with all assays having excellent agreement at high viral loads (CT < 20).
Aurelie Minelle Kengni Ngueko, Sandrine Claire Djupsa Ndjeyep, Ezechiel Ngoufack Jagni Semengue, Alex Durand Nka, Collins Ambe Chenwi, Aude Christelle Ka'e, Yagai Bouba, Jeremiah Efakika Gabisa, Evariste Molimbou, Naomi‐Karell Etame, Tatiana Anim‐Keng Tekoh, Rachel Audrey Nayang Mundo, Pamela Patricia Tueguem, Vincent Kamael Mekel, Hugues Mba, Désiré Takou, Grace Angong Beloumou, Michel Carlos Tommo Tchouaket, Larissa Gaelle Moko Fotso, Derrick Tambe Ayuk, Christian Ngongang Ouankou, Claudia Alteri, Luna Colagrossi, Yap Boum II, Halle Gregory Eddy Ekane, Francesca Ceccherini‐Silberstein, Vittorio Colizzi, Nicaise Ndembi, Alfred K. Njamnshi, Alexis Ndjolo, Carlo‐Federico Perno, Maria‐Mercedes Santoro, Joseph Fokam   +32 more
wiley   +1 more source

The seven enigmas of SARS-CoV-2: from the past to the future. [PDF]

J Hum Immun
Andreakos E, Arkin L, Bastard P, Bolze A, Borghesi A, Brodin P, Casanova JL, Casari G, Cobat A, Drolet B, Fellay J, Hsieh E, Meyts I, Mogensen TH, Sancho-Shimizu V, Spaan AN, Su HC, Vinh DC, Yatim A, Zhang Q, Zhang SY, COVID Human Genetic Effort+.   +21 more
europepmc   +1 more source

Attention‐deficit hyperactivity disorder in children and young persons during the COVID‐19 pandemic. A temporal trends analysis of electronic heath records in Greater Manchester, England

JCPP Advances, EarlyView.
Abstract Background The incidence of attention‐deficit hyperactivity disorder (ADHD) in children and young people has increased in recent years. Disease frequency varies according to sociodemographic characteristics. There are seasonal patterns in ADHD diagnosis and prescribing with rates falling during school holidays.
Louise Hussey, Evangelos Kontopantelis, Pearl L. H. Mok, Darren M. Ashcroft, Shruti Garg, Carolyn A. Chew‐Graham, Karina Lovell, Roger T. Webb   +7 more
wiley   +1 more source

Genomic epidemiology of SARS-CoV-2 in Peru from 2020 to 2024. [PDF]

Commun Med (Lond)
Sobkowiak B, Langdon A, Romero PE, Carrasco-Escobar G, Villa D, Cava Miller R, Cornejo Villanueva V, Dávila-Barclay A, Cuicapuza D, Salvatierra G, González L, Ayzanoa B, Huancachoque J, Marcos-Carbajal P, Gómez de la Torre JC, Barletta C, Chenet SM, Tapia-Limonchi R, Ballón J, Fernández P, Valderrama R, Leguía M, Delgado-Ratto C, Gotuzzo E, Zamudio C, Lescano W, Cárcamo C, Hurtado V, Lope-Pari P, Padilla-Rojas C, Jiménez-Vásquez V, Escalante-Maldonado O, Araujo-Castillo RV, Cabezas C, Colijn C, Tsukayama P.   +35 more
europepmc   +1 more source

Two causes of COVID‐19‐related myocardial injury‐associated cardiogenic shock: Myocarditis and microvascular thrombosis

ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai, Hirohiko Aikawa, Yoshiaki Morita, Keiko Ohta‐Ogo, Teruo Noguchi   +4 more
wiley   +1 more source

Prevalence and costs of US pediatric hospitalizations, 2022

Journal of Hospital Medicine, EarlyView.
Abstract Background Pediatric hospitalizations represent an evolving component of US healthcare utilization. The coronavirus disease 2019 (COVID‐19) pandemic hastened rising mental health visits and shrinking rural hospital capacity. Understanding contemporary patterns in pediatric hospitalizations is critical to inform health system planning and ...
Anna J. Lytchakov, Nathan M. Money, Jennifer A. Hoffmann, Todd A. Florin, Kenneth A. Michelson, Sriram Ramgopal   +5 more
wiley   +1 more source

Hepatopulmonary syndrome as presentation of pediatric metabolic dysfunction‐associated steatohepatitis

JPGN Reports, EarlyView.
Abstract Childhood obesity is rising and leading to serious co‐morbidities, among which is metabolic dysfunction‐associated steatotic liver disease (MASLD) predisposing individuals to cirrhosis. We describe a young 11‐year‐old Hispanic male who presented with hepatopulmonary syndrome secondary to cirrhotic portal hypertension from metabolic dysfunction‐
Shruti Sakhuja, Stacey S. Beer, Kalyani R. Patel, Alexiss M. Williams, Nhu Thao Galvan, John A. Goss, Krupa R. Mysore   +6 more
wiley   +1 more source