Results 21 to 30 of about 805,395 (207)

Detection of SARS-CoV-2 in Different Types of Clinical Specimens.

open access: yesJournal of the American Medical Association (JAMA), 2020
This study describes results of PCR and viral RNA testing for SARS-CoV-2 in bronchoalveolar fluid, sputum, feces, blood, and urine specimens from patients with COVID-19 infection in China to identify possible means of non-respiratory transmission.
Wenling Wang   +6 more
semanticscholar   +1 more source

Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection

open access: yesScience, 2021
Variable memory Immune memory against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) helps to determine protection against reinfection, disease risk, and vaccine efficacy.
J. Dan   +20 more
semanticscholar   +1 more source

Characteristics of SARS-CoV-2 and COVID-19

open access: yesNature Reviews Microbiology, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory disease, named ‘coronavirus disease 2019’ (COVID-19), which ...
Ben Hu, Hua Guo, P. Zhou, Zhènglì Shí
semanticscholar   +1 more source

Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England

open access: yesScience, 2021
UK variant transmission Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has the capacity to generate variants with major genomic changes. The UK variant B.1.1.7 (also known as VOC 202012/01) has many mutations that alter virus attachment and
N. Davies   +22 more
semanticscholar   +1 more source

SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients

open access: yesNew England Journal of Medicine, 2020
SARS-CoV-2 Viral Load in Upper Respiratory Specimens The authors report results of an analysis of nasal and throat swabs from 17 patients in Zhuhai, China, who had received a diagnosis of Covid-19....
L. Zou   +15 more
semanticscholar   +1 more source

A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing

open access: yesNature, 2020
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has infected over 2.3 million people, led to the death of more than 160,000 individuals
D. Gordon   +124 more
semanticscholar   +1 more source

SARS-CoV-2 variants, spike mutations and immune escape

open access: yesNature Reviews Microbiology, 2021
Although most mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome are expected to be either deleterious and swiftly purged or relatively neutral, a small proportion will affect functional properties and may alter ...
William T. Harvey   +10 more
semanticscholar   +1 more source

Mechanisms of SARS-CoV-2 entry into cells

open access: yesNature reviews. Molecular cell biology, 2021
The unprecedented public health and economic impact of the COVID-19 pandemic caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been met with an equally unprecedented scientific response.
C. B. Jackson   +3 more
semanticscholar   +1 more source

Cardiovascular disease in SARS‐CoV‐2 infection

open access: yesClinical & Translational Immunology, 2021
Pre‐existing cardiovascular disease (CVD) increases the morbidity and mortality of COVID‐19 and is strongly associated with poor disease outcomes. However, SARS‐CoV‐2 infection can also trigger de novo acute and chronic cardiovascular disease.
Kei Sato   +5 more
doaj   +1 more source

Racing for a SARS‐CoV‐2 vaccine

open access: yesEMBO Molecular Medicine, 2021
Graphical Abstract Interview with EMBO Members Özlem Türeci and Uğur Şahin, BioNTech, conducted by science journalist Kai Kupferschmidt.
Özlem Türeci, Uğur Şahin
doaj   +1 more source

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