Results 61 to 70 of about 1,293,835 (325)

Evolutionary Multi-Objective Design of SARS-CoV-2 Protease Inhibitor Candidates

, 2020
Computational drug design based on artificial intelligence is an emerging research area. At the time of writing this paper, the world suffers from an outbreak of the coronavirus SARS-CoV-2.
A Alhossary, CA Lipinski, CA Nicolaou, D Douguet, D Weininger, E van der Horst, E Zitzler, GR Bickerton, H Nguyen, HG Beyer, K Deb, L Zhang, N Brown, N Brown, O Trott, P Ertl, P Ertl, RF de Freitas, RV Devi, SCH Pegg, SS Kaplan, T Gaillard, T Krause, TT Wager, W Dai   +24 more
core   +1 more source

COVID-19 publications: Database coverage, citations, readers, tweets, news, Facebook walls, Reddit posts [PDF]

, 2020
© 2020 The Authors. Published by MIT Press. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.1162/qss_a_00066The COVID ...
Adie E., Chen Q., Clark F., Colavizza G., Costas R., de Solla Price D., Delwiche F. A., Fairclough R., Gunn W., Harzing A. W., Haustein S., Haustein S., Haustein S., Holmberg K., Ioannidis J. P., Kostoff R. N., Kousha K., Kousha K., Lewison G., Merchant R. M., Mohammadi E., Mohammadi E., Mohammadi E., Mohammadi E., Mohammadi E., Orduña-Malea E., Ortega J. L., Ortega J. L., Ovadia S., Pouris A., Pouris A., Rethlefsen M. L., Robinson-García N., Robinson-García N., Song P., Stegehuis C., Stoddard G., Sud P., Thelwall M., Thelwall M., Thelwall M., Thelwall M., Thelwall M., Thelwall M., Thelwall M., Thelwall M., Tian D., Torres-Salinas D., Van Noorden R., Wallace M. L., WHO, Yu H., Zahedi Z., Zahedi Z., Zahedi Z.   +54 more
core   +2 more sources

Aptamer‐based strategies against SARS‐CoV‐2 viruses

BMEMat, 2023
The COVID‐19 pandemic, caused by SARS‐CoV‐2, has seriously threatened human life and security in recent years and has had a serious impact on economic development. A range of strategies, including antibodies, small‐molecule agents and vaccines, have been
Yihao Huang, Ximing Chen, Jialu Zhang, Wenhai Tian, Siwen Liu, Rachel Chun‐Yee Tam, Chaoyong Yang, Yanling Song   +7 more
doaj   +1 more source

Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

Nature Communications, 2020
Since 2002, beta coronaviruses (CoV) have caused three zoonotic outbreaks, SARS-CoV in 2002–2003, MERS-CoV in 2012, and the newly emerged SARS-CoV-2 in late 2019. However, little is currently known about the biology of SARS-CoV-2.
Xiuyuan Ou, Yan Liu, X. Lei, Pei Li, Dan Mi, L. Ren, Li Guo, Ruixuan Guo, Ting Chen, Jiaxin Hu, Zichun Xiang, Z. Mu, Xing Chen, Jieyong Chen, Keping Hu, Q. Jin, Jianwei Wang, Zhaohui Qian   +17 more
semanticscholar   +1 more source

Reliable and accurate diagnostics from highly multiplexed sequencing assays [PDF]

, 2020
Scalable, inexpensive, and secure testing for SARS-CoV-2 infection is crucial for control of the novel coronavirus pandemic. Recently developed highly multiplexed sequencing assays (HMSAs) that rely on high-throughput sequencing can, in principle, meet ...
Bloom, Joshua S., Booeshaghi, A. Sina, Cooper, Aaron R., Gehring, Jase, Kosuri, Sriram, Lubock, Nathan B., Luebbert, Laura, Pachter, Lior, Simpkins, Scott W.   +8 more
core  

Droplet evaporation residue indicating SARS-COV-2 survivability on surfaces

, 2020
SARS-CoV-2 survives and remains viable on surfaces for several days under different environments as reported in recent studies. However, it is unclear how the viruses survive for such a long time and why their survivability varies across different ...
He, Zilong, Hong, Jiarong, Kumar, S. Santosh, Li, Jiaqi, Shao, Siyao, Sokoloff, J. B.   +5 more
core   +1 more source

Molecular Crowding Modulates SARS‐CoV‐2 Aptamer Affinity

Small Structures, 2023
SARS‐CoV‐2 aptamer is a favorable candidate for the recognition and detection of SARS‐CoV‐2, owing to its small size and easy synthesis. However, the issue of compromised binding affinities in real samples and targeting mutant SARS‐CoV‐2 hinder wide ...
Ting Song, Miao Sun, Jialu Zhang, Yinzhu Lu, Shuang Wan, Chaoyong Yang, Yanling Song   +6 more
doaj   +1 more source

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

Nature Microbiology, 2020
Over the past 20 years, several coronaviruses have crossed the species barrier into humans, causing outbreaks of severe, and often fatal, respiratory illness. Since SARS-CoV was first identified in animal markets, global viromics projects have discovered
M. Letko, A. Marzi, V. Munster
semanticscholar   +1 more source

The pulmonary-proteoliposome as a new therapeutic approach for Coronaviruses [PDF]

, 2020
We are proposing the use of pulmonary-proteoliposome as a new therapeutic approach for Coronaviruses. The designed strategy represents a potential treatment to reduce the overall viral load in the lungs and to help the immune system to successfully stave
Feliciello, Isidoro, Procino, Alfredo
core   +1 more source

Erythema Multiforme Major following SARS‐CoV‐2 vaccine

Clinical Case Reports, 2021
Erythema multiforme major, an immune‐mediated skin reaction to infections or medications with oral involvement, should be taken into account as a potential side effect of several vaccines, including SARS‐CoV‐2.
Alberto Maria Saibene, Andrea Alliata, Anna Teresa Cozzi, Alice Ottavi, Sofia Spagnolini, Carlotta Pipolo, Alberto Maccari, Giovanni Felisati   +7 more
doaj   +1 more source