Results 151 to 160 of about 476,350 (261)

Substrate‐Selective Inhibition of the SARS‐CoV‐2 Papain‐Like Protease: Inhibition of Hydrolysis of Human Over Viral Substrates

Chemistry – A European Journal, EarlyView.
The SARS‐CoV‐2 papain‐like protease (PLpro) is a medicinal chemistry target. Here we report mass spectrometry assays employing oligopeptide substrates based on the sequences of the viral polyproteins 1a/1ab and on an ISG15‐modified human protein, which enabled the identification of substrate‐selective PLpro inhibitors.
Sakshi Sharma, Peter A. C. Wing, Wojtek Treyde, Shyam Basak, Simeon D. Draganov, Taylah Andrews‐Clark, Eidarus Salah, Petra Lukacik, Claire Strain‐Damerell, Adán Pinto‐Fernández, Martin A. Walsh, Fernanda Duarte, Christopher J. Schofield, Lennart Brewitz   +13 more
wiley   +1 more source

SARS-CoV-2 Variants and Immune Evasion: Mapping the Future of Vaccine Design. [PDF]

Rev Med Virol
Uzer F, Erendor F, Sanlioglu S.
europepmc   +1 more source

Artificial intelligence in enzyme catalysis: Emerging trends and applications in biocatalyst engineering

The Canadian Journal of Chemical Engineering, EarlyView.
Schematic representation of artificial intelligence approaches in enzyme catalysis, integrating bibliometric analysis, emerging research trends, and machine learning tools for enzyme design, prediction, and industrial biocatalytic applications. Abstract This study systematically explores the applications of artificial intelligence (AI) in enzyme ...
Misael Bessa Sales, Francisco Izaias da Silva Aires, Paulo Gonçalves de Sousa Junior, Calebe Da Rocha Silva, Emanuel Lino Rodrigues, Maria Cristiane Martins de Souza, José C. S. dos Santos   +6 more
wiley   +1 more source

Development of IgA vasculitis after SARS‐CoV‐2 vaccination

Journal of Cutaneous Immunology and Allergy, 2022
Yasuaki Ogura, Hiroki Morimoto, Masaki Otsuka, Yoshiki Tokura   +3 more
doaj   +1 more source

Tick‐Tock, the Time Has Come: Leveraging TikTok to Understand, Prevent, and Treat Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective TikTok—a highly engaging social media platform with a powerful algorithm that displays short videos—has become massively popular in recent years. As research highlights the concerning relationship between image‐based content on social media and disordered eating symptoms, TikTok may serve as an optimal platform to understand eating ...
Macarena Kruger, Isabella Pruscino, Caroline G. Martin, Elizabeth A. Velkoff   +3 more
wiley   +1 more source

Cutaneous Lymphomas and Lymphoproliferative Disorders Associated With SARS-CoV-2 Vaccination: A Systematic Review. [PDF]

J Skin Cancer
Mussi M, Zengarini C, Corrà A, Brunetti T, Natale A, La Placa M, Piraccini BM, Guglielmo A, Pileri A.   +8 more
europepmc   +1 more source

The origin of SARS-CoV-2 [PDF]

The Lancet Infectious Diseases, 2020
openaire   +2 more sources

Sex Differences in Social, Health, and Lifestyle Characteristics Associated With Binge‐Eating Behaviors: Results From a French National Random Population‐Based Study

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To explore sex differences in social, health and lifestyle characteristics associated with binge‐eating behaviors in a large population‐based study. Method This study included 84,995 participants (women 52.1%) aged ≥ 15 years from the French national random population‐based EpiCov cohort.
Junko Kose, Nathalie Godart, Anne Pastorello, Caroline Huas, Alexandra Rouquette, EpiCov Study Group, Josiane Warszawski, Nathalie Bajos, Guillaume Bagein, François Beck, Emilie Counil, Florence Jusot, Nathalie Lydié, Claude Martin, Laurence Meyer, Philippe Raynaud, Alexandra Rouquette, Ariane Pailhé, Delphine Rahib, Patrick Sillard, Rémy Slama, Alexis Spire   +21 more
wiley   +1 more source

Structural mimics of SARS-CoV-2. [PDF]

Infection
Killassy N, Arbuthnot P, Maepa MB.
europepmc   +1 more source

SARS-CoV-2 Spike Protein's Structural Dynamics Affect the Activity of the Bebtelovimab Antibody. [PDF]

J Chem Inf Model
Mansur M, Hong H, Singh S, Liu Z, Azevedo M, Li D, Knox B, Hasan MR, Tong W, Baudry J, Ning B.   +10 more
europepmc   +1 more source