Results 161 to 170 of about 869,733 (343)

SARS‐CoV‐2 infection in lung transplant recipients induces circulating exosomes with SARS‐CoV‐2 spike protein S2

Clinical and Translational Medicine, 2021
Sandhya Bansal, Sofya Tokman, Timothy Fleming, Gabriel N. Maine, Kristina Sanborn, Ramsey Hachem, Ankit Bharat, Michael A. Smith, Ross M. Bremner, T. Mohanakumar   +9 more
doaj   +1 more source

Hepatitis E Virus ORF1 Polyprotein Harbors a Pocket‐Like Cavity That Is Vital for Virus Replication and Represents a Novel Antiviral Target

Advanced Science, EarlyView.
Within the hepatitis E virus (HEV) ORF1 polyprotein, the X domain interacts with viral RNA‐dependent RNA polymerase (RdRp), forming a functional “pocket‐like” cavity (PC) that is crucial for viral replication. Structure‐based screening, surface plasmon resonance (SPR) assays, and HEV model validation collectively identify saikosaponin D and ...
Xiaohui Ding, Dou Zeng, Dan Liu, Yingying Bian, Bin Li, Zheng Li, Qiudi Li, Shiquan Liang, Yunlong Si, Qili Yao, Yibo Ding, Jiahui Zhu, Xiangyang Li, Kuiyang Zheng, Hongbo Guo, Wenshi Wang   +15 more
wiley   +1 more source

Colorimetric Detection of SARS-CoV-2 and Drug-Resistant pH1N1 Using CRISPR/dCas9

, 2020
Jeong Moon, Hyung-Jun Kwon, Dongeun Yong, In-Chul Lee, Hongki Kim, Hyunju Kang, Eun‐Kyung Lim, Kyu‐Sun Lee, Juyeon Jung, Hyun Gyu Park, Taejoon Kang   +10 more
openalex   +1 more source

The origin of SARS-CoV-2 [PDF]

The Lancet Infectious Diseases, 2020
openaire   +3 more sources

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges

International Journal of Antimicrobial Agents, 2020
Chih-Cheng Lai, Tzu-Ping Shih, W. Ko, H. Tang, P. Hsueh   +4 more
semanticscholar   +1 more source

The NSP5, ORF6 and NSP13 of SARS‐CoV‐2 Cooperate to Modulate Inflammatory Cell Death Activation

Advanced Science, EarlyView.
ZBP1 is capable of initiating a large cell death complex to induce programmed cell death during SARS‐CoV‐2 infection. However, SARS‐CoV‐2 can inhibit the activation of ZBP1‐mediated cell death by targeting key components of this complex. This suppression of ZBP1‐mediated cell death may account for the increased mortality observed in patients co ...
Huan Wang, Mengdi Liang, Jing Zhang, Hua Tong, Fenfen Zhang, Ying Liu, Pui Wang, Mengmeng Chang, Fei Han, Siwen Liu, Yongping Lin, Wenjun Song, Rajendra Karki, Peihui Wang, Honglin Chen, Yang Liu, Min Zheng   +16 more
wiley   +1 more source

“Recordando la parotiditis en la era del SARS-CoV-2”

, 2000
Anabela Salgueiro Marques, Joana Diogo, Carolina Gomes Coelho   +2 more
openalex   +1 more source

Identification of inhibitors of SARS-CoV-2 3CL-Pro enzymatic activity using a small molecule in-vitro repurposing screen

, 2020
Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen, Francesca Esposito, Laura Vangeel, Markus Wolf, Bernhard Ellinger, Carsten Claussen, Gerd Geißlinger, Angela Corona, Daniela Iaconis, Carmine Talarico, Candida Manelfi, Rolando Cannalire, Giulia Rossetti, Jonas Goßen, Simone Albani, Francesco Musiani, Katja Herzog, Ye Yang, Barbara Giabbai, Nicola Demitri, Dirk Jochmans, Steven De Jonghe, Jasper Rymenants, Vincenzo Summa, Enzo Tramontano, Andrea R. Beccari, Pieter Leyssen, Paola Storici, Johan Neyts, Philip Gribbon, Andrea Zaliani   +32 more
openalex   +1 more source

Variants of SARS-CoV-2 [PDF]

JAMA, 2021
Preeti N. Malani, Adam S. Lauring
openaire   +2 more sources

RESP2: An Uncertainty Aware Multi‐Target Multi‐Property Optimization AI Pipeline for Antibody Discovery

Advanced Science, EarlyView.
RESP2, an enhanced antibody discovery pipeline for multi‐target and multi‐property optimization, identifies antibodies with optimized developability and broad affinity to multiple antigen variants. In silico evaluation shows RESP2 outperforms leading AI methods, achieving ≥85% success rates.
Jonathan Parkinson, Ryan Hard, Young Su Ko, Wei Wang   +3 more
wiley   +1 more source