Results 171 to 180 of about 1,228,387 (374)
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac+7 more
wiley +1 more source
Surveillance of seasonal respiratory viruses among Chilean patients during the COVID‐19 pandemic
Luis A. Alonso‐Palomares+8 more
doaj +1 more source
Functionalized Antifouling Polymer Brushes for Biospecific Surfaces
Modern biosensors offer high sensitivity but often struggle with long‐term stability and selectivity for specific targets. Antifouling polymer brushes help enhance both stability and selectivity. In this review, we compare recent antifouling coatings, their design parameters, and how they are integrated with biorecognition elements for improved ...
Erik J. Postma+4 more
wiley +1 more source
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
J. Lan+10 more
semanticscholar +1 more source
Detecting single molecules on large interfaces is challenging due to minimal perturbations on the sensing surface. Some biological systems achieve this feat using amplification mechanisms, but their molecular foundations remain unclear. To investigate, a Design of Experiments (DoE) approach examines how pH and ionic strength in conditioning solutions ...
Michele Catacchio+9 more
wiley +1 more source
Advancing COVID-19 diagnostics:rapid detection of intact SARS-CoV-2 using viability RT-PCR assay [PDF]
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). Commonly used methods for both clinical diagnosis of SARS-CoV-2 infection and management of infected patients involve the detection of viral RNA, but
Dickman, Mor M.+12 more
core +1 more source
Fetal Surgery in the Era of SARS-CoV-2 Pandemic: A Single-Institution Review [PDF]
Kavita Narang+10 more
openalex +1 more source
A simple method relying on surface‐initiated RAFT polymerization is presented using a mixed‐chain transfer agent (mixed‐CTA) approach to grow well‐defined poly(HPMAm) brushes with precise control, achieving >70 nm thickness in 4 h at moderate temperature, 50 °C. Abstract Over three decades, efforts to prevent non‐specific protein adsorption on surfaces
Manisha Singh+4 more
wiley +1 more source
Photonic Crystal Enhanced Microscopy on a 2D Photonic Crystal Surface
This work demonstrates the design, fabrication, and the first‐time test of a 2D photonic crystal surface for photonic resonator absorption microscopy. The designed surface uniformly enhances electromagnetic near fields, achieving > 100% improved detecting uniformity for surface‐captured AuNPs from a blocking biosensor assay aimed for detecting SARS‐CoV‐
Weinan Liu+5 more
wiley +1 more source