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SARS-CoV-2 pathogenesis

Nature Reviews Microbiology, 2022
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop a mild to moderate disease with virus replication restricted mainly to the upper airways, some progress to having a life-threatening pneumonia.
Mart M. Lamers, Bart L. Haagmans
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SARS-CoV-2

2022
The basic proteinase of SARS-CoV-2 M^pro virus (3CLpro) controls a number of activities of the replication complex of the virus and is therefore a target for the development of specific inhibitors. In the development of drugs against SARS-CoV-2, much attention is paid to previously known effective compounds.
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SARS-CoV-2 dilated cardiomyopathy

British Journal of Cardiology, 2022
SARS-CoV-2 is an emerging cause of viral myocarditis that generates multiple complications, such as dilated cardiomyopathy. We describe a young, obese male patient with severe myocardial involvement by the SARS-CoV-2 virus, who presented with chest pain, elevated cardiac enzymes, non-specific electrocardiographic findings, echocardiogram with evidence ...
Manuel Felipe, Cáceres-Acosta   +2 more
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Transmission of SARS-CoV-2

Annals of Internal Medicine, 2021
Eric A. Meyerowitz   +3 more
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