Results 11 to 20 of about 1,303,574 (326)
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
Science, 2020 How SARS-CoV-2 binds to human cells Scientists are racing to learn the secrets of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2), which is the cause of the pandemic disease COVID-19. The first step in viral entry is the binding of the viral
R. Yan +5 more
semanticscholar +1 more source
The proximal origin of SARS-CoV-2
Nature Network Boston, 2020 SARS-CoV-2 is the seventh coronavirus known to infect humans; SARSCoV, MERS-CoV and SARS-CoV-2 can cause severe disease, whereas HKU1, NL63, OC43 and 229E are associated with mild symptoms6. Here we review what can be deduced about the origin of SARS-CoV-
K. Andersen +5 more
semanticscholar +1 more source
Frontiers in Microbiology, 2022 Orthopoxviruses (OPXVs) not only infect their natural hosts, but some OPXVs can also cause disease in humans. Previously, we partially characterized an OPXV isolated from an 18-year-old male living in Northern Norway.
Diana Diaz-Cánova +4 more
doaj +1 more source
Detection of SARS-CoV-2 in Different Types of Clinical Specimens.
Journal of the American Medical Association (JAMA), 2020 This study describes results of PCR and viral RNA testing for SARS-CoV-2 in bronchoalveolar fluid, sputum, feces, blood, and urine specimens from patients with COVID-19 infection in China to identify possible means of non-respiratory transmission.
Wenling Wang +6 more
semanticscholar +1 more source
The design of Indonesian SARS‐CoV‐2 primers based on phylogenomic analysis of the SARS‐CoV‐2 clades
Indonesian Journal of Biotechnology, 2022 Molecular detection needs to be augmented for COVID‐19 detection in Indonesia using the PCR method with primer‐based gene analysis. This is necessary because the RNA of the SARS‐CoV‐2 virus, the causative infectious agent of the pandemic, has been ...
Tsania Taskia Nabila +3 more
doaj +1 more source
Physiological Reports, 2021 The objective of this review is to give an overview of the pathophysiological effects of the Coronavirus Disease 2019 (COVID‐19) in relation to hypertension (HT), with a focus on the Renin–Angiotensin–Aldosterone System (RAAS) and the MAS receptor. HT is
Briyanth Ravichandran +5 more
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Nature Microbiology, 2020 The present outbreak of a coronavirus-associated acute respiratory disease called coronavirus disease 19 (COVID-19) is the third documented spillover of an animal coronavirus to humans in only two decades that has resulted in a major epidemic.
Alexander E. Susan C. Ralph S. Raoul J. Christian Anastasia Gorbalenya Baker Baric de Groot Drosten Gulyaeva H +17 more
semanticscholar +1 more source
SARS-CoV-2 variants, spike mutations and immune escape
Nature Reviews Microbiology, 2021 Although most mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome are expected to be either deleterious and swiftly purged or relatively neutral, a small proportion will affect functional properties and may alter ...
William T. Harvey +10 more
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Characteristics of SARS-CoV-2 and COVID-19
Nature Reviews Microbiology, 2020 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory disease, named ‘coronavirus disease 2019’ (COVID-19), which ...
Ben Hu, Hua Guo, P. Zhou, Zhènglì Shí
semanticscholar +1 more source
Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection
Science, 2021 Variable memory Immune memory against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) helps to determine protection against reinfection, disease risk, and vaccine efficacy.
J. Dan +20 more
semanticscholar +1 more source