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Structural model of SARS-CoV-2 including the X rays structure of the spikes (PDB ID 6VSB). The model is composed of cryoEM density from SARS-CoV-1 for the core and SARS-CoV-2 spikes pdbs.
Steinbauer, M., Böckler, D.
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A previously immune-naive world population is experiencing natural infection with SARS-CoV-2. Severe COVID-19 predominantly impacts adults, yet multisystem inflammatory disorder primarily impacts children. Herein, we discuss known clinical and biological features of SARS-CoV-2 in children and reflect on currently identified immune features and discuss ...
Bogunovic, Dusan, Merad, Miriam
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Epidemiology of SARS-CoV-2 [PDF]
Abstract Purpose SARS-CoV-2 is a recently emerged ß-coronavirus. Here we present the current knowledge on its epidemiologic features. Methods Non-systematic review.
Salzberger, Bernd +7 more
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There is no “origin” to SARS-CoV-2
Since the beginning of the COVID-19 pandemic in 2020 caused by SARS-CoV-2, the question of the origin of this virus has been a highly debated issue. Debates have been, and are still, very disputed and often violent between the two main hypotheses: a natural origin through the "spillover" model or a laboratory-leak origin.
Frutos, Roger +3 more
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first identified in 2020 and has led to an unprecedented global pandemic. Understanding the virology behind SARS-CoV-2 infection has provided key insights into our efforts to develop antiviral agents and control the COVID-19 pandemic.
Li, Yijia, Li, Jonathan Z.
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SARS-CoV-2 virus has become a global health problem that has caused millions of deaths worldwide. The infection can present with multiple clinical features ranging from asymptomatic or mildly symptomatic patients to patients with severe or critical illness that can even lead to death.
Dennis Jiménez, Marbel Torres Arias
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Bronchiolitis and SARS-CoV-2 [PDF]
BackgroundIt has been speculated that the SARS-CoV-2 was already widespread in western countries before February 2020.MethodsWe gauged this hypothesis by analysing the nasal swab of infants with either bronchiolitis or a non-infectious disease admitted to the Ospedale Maggiore, Milan (one of the first epicentres of SARS-CoV-2 outbreak in Europe) from ...
Milani G. P. +10 more
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Reporte nº17 – Provincia de Córdoba – 19 de marzo de 2021. Consorcio interinstitucional para la Secuenciación del genoma y estudios genómicos de SARS-COV-2 (Proyecto PAIS) [PDF]
Fil: Consorcio Argentino de Genómica de SARS-CoV-2; Argentina.Fil: Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Instituto de Virología Dr. José María Vanella; Argentina.Fil: Gobierno de la Provincia de Córdoba.
Gobierno de la Provincia de Córdoba. Ministerio de Salud. Laboratorio Central +2 more
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SummaryThe recent emergence of a new coronavirus (severe acute respiratory syndrome coronavirus‑2, SARS-CoV-2) that is transmitted efficiently among humans and can result in serious disease and/or death has become a global threat to public health and economy.
Heinz, Franz X., Stiasny, Karin
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It has been posited SARS-CoV-2 contains at least one unique superantigen-like motif not found in any other SARS or endemic coronaviruses. Superantigens are potent antigens that can send the immune system into overdrive. SARS-CoV-2 causes many of the biological and clinical consequences of a superantigen, and, in the context of reinfection and waning ...
Adam Hamdy, Anthony Leonardi
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