Results 231 to 240 of about 1,228,387 (374)

Boosting test-efficiency by pooled testing strategies for SARS-CoV-2

, 2020
Rudolf Hanel, Stefan Thurner
openalex   +2 more sources

Pharmacotherapeutics of SARS-CoV-2

Journal of Family Medicine and Primary Care, 2022
Harish Gupta, Nitu Nigam, Satish Kumar
openaire   +3 more sources

Neutrophil–Endothelium Interaction Mediated by S100A9 Promotes Pulmonary Vascular Remodeling During Pulmonary Hypertension

Advanced Science, EarlyView.
This study investigates the critical mechanisms underlying pulmonary hypertension progression, with a focus on the novel role of neutrophil‐derived S100A9 in endothelial dysfunction‐mediated pulmonary vascular remodeling. By integrating human lung samples, multi‐omics analyses, animal models, and mechanistic in vitro studies, it is revealed that how ...
Yu Guo, Zhenqiang Gao, Ruoyang Zhang, Huanyu Long, Muzhi Zhang, Lin Liu, Zhe An, Yuezhe Shi, Ye Cui, Yufeng Jia, Lei Wang, Ying Sun, Jie Liu, Wei Wang   +13 more
wiley   +1 more source

Interim guidance for antigen testing for SARS-CoV-2 [PDF]

Updated Jan. 20, 2022General Guidance -- Regulatory Requirements for Using Antigen Tests for SARS-CoV-2 -- Performance of Antigen Tests for SARS-CoV-2 -- Processing of Antigen Tests for SARS-CoV-2 -- Interpreting the Results of Antigen Testing for SARS ...

core  

School education during the SARS-CoV-2 pandemic - Which concept is safe, feasible and environmentally sound?

, 2020
Christian J. Kähler, Thomas Fuchs, Benedikt Mutsch, Rainer Hain   +3 more
openalex   +1 more source

Engineered Dual‐Function Antibody‐Like Proteins to Combat SARS‐CoV‐2‐Induced Immune Dysregulation and Inflammation

Advanced Science, EarlyView.
Engineered antibody‐like proteins block the SARS‐CoV‐2 spike protein from binding to host receptors and suppress immune overactivation through an MBL‐based scaffold. These dual‐function proteins effectively alleviate inflammation, complement activation, and lung injury, offering a promising therapeutic strategy against severe COVID‐19 and its ...
Yizhuo Wang, Chenwu Bai, Kerui Hou, Zhen Zhang, Ming Guo, Xin Wang, Fan Yang, Xin Liu   +7 more
wiley   +1 more source

Platelets Can Associate With SARS-CoV-2 RNA and Are Hyperactivated in COVID-19

, 2020
Younes Zaid, Florian Puhm, Isabelle Allaeys, Abdallah Naya, Mounia Oudghiri, Loubna Khalki, Youness Limami, Nabil Zaïd, Khalid Sadki, Rafiqua Ben El Haj, Wissal Mahir, Lamiae Belayachi, Bouchra Belefquih, A. Benouda, Amine Cheikh, Marc‐André Langlois, Yahia Cherrah, Louis Flamand, Fadila Guessous, Éric Boilard   +19 more
openalex   +1 more source

Author Correction: A role for Biofoundries in rapid development and validation of automated SARS-CoV-2 clinical diagnostics [PDF]

, 2020
Michael A. Crone, Miles Priestman, Marta Ciechonska, Kirsten Jensen, David Sharp, Arthi Anand, Paul Randell, Marko Storch, Paul S. Freemont   +8 more
openalex   +1 more source

The Neglected Role of GSDMD C‐Terminal in Counteracting Type I Interferon Signaling

Advanced Science, EarlyView.
The C‐terminal domain of Gasdermin D (GSDMD‐CT) shows functions beyond pyroptosis. GSDMD‐CT negatively regulates IFN‐I signaling during viral infection by triggering autophagic degradation of RIG‐I and TBK1. GSDMD‐CT interacts with retinoic acid‐inducible gene‐I (RIG‐I) and tank‐binding kinase 1 (TBK1), leading to TRIM28‐mediated ubiquitination and ...
Weilv Xu, Suhui He, Wen Shi, Jinxia Xu, Shiyang Liu, Zexu Yu, Danyue Li, Qiao Jin, Yumeng Wang, Zian Zhang, Qian Lv, Yuanxiang Ge, Yunjie Li, Xinyue Li, Nan Chen, Xinyu Fu, Yang Yang, Fushan Shi   +17 more
wiley   +1 more source

Atlas of ACE2 gene expression reveals novel insights into transmission of SARS-CoV-2

, 2020
Kun Sun, Liuqi Gu, Li Ma, Yunfeng Duan
openalex   +1 more source