Results 231 to 240 of about 926,443 (292)

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Selection and Characterization of SARS-CoV-2 Spike Binding Clickmers. [PDF]

Chembiochem
Moradzadeh N, Jonczyk A, Schmitz A, Fieberg V, Civit L, Valero J, Famulok M, Mayer G.   +7 more
europepmc   +1 more source

On the analyzing of bifurcation properties of the one‐dimensional Mackey–Glass model by using a generalized approach

Mathematical Methods in the Applied Sciences, EarlyView.
The goal of this work is to look at how a nonlinear model describes hematopoiesis and its complexities utilizing commonly used techniques with historical and material links. Based on time delay, the Mackey–Glass model is explored in two instances. To offer a range, the relevance of the parameter impacting stability (bifurcation) is recorded.
Shuai Zhang, Yaya Wang, Hongyin Geng, Wei Gao, Esin Ilhan, Haci Mehmet Baskonus   +5 more
wiley   +1 more source

SARS-CoV-2 and Influenza Co-Circulation and Co-Vaccination: A Narrative Review. [PDF]

Vaccines (Basel)
Kamransarkandi M, Varyushina EA, Gorshkov AN, Stukova MA.   +3 more
europepmc   +1 more source

Co-Culture Systems to Study Epithelial-Immune Interactions During SARS-CoV-2 Infection. [PDF]

Curr Protoc
Randell SH, Barnett KC.
europepmc   +1 more source

Imaging Venous Transit Time and Blood–Brain Barrier Permeability of the Deep Brain

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Imaging of venous vessels with advanced pulse sequences allows the assessment of important hemodynamic parameters. Previous work has measured venous transit time (VTT) and blood–brain barrier (BBB) water permeability in cortical tissue.
Wen Shi, Jie Song, Jiani Wu, Yifan Gou, Zhiyi Hu, Vivek Yedavalli, Zixuan Lin, Hanzhang Lu   +7 more
wiley   +1 more source

Two years of SARS-CoV-2 genomic surveillance capacity development in Guinea. [PDF]

Sci Rep
Magassouba N, Gustani-Buss E, Ifono K, Nelson EV, Camara J, Annibaldis G, Renevey A, Hinzmann J, Hinrichs M, Ryter S, Emua E, Millimono SL, Kolie E, Condé M, Sylla B, Ibrahim N, Mely S, Soubrier H, de Bellocq JG, Escudero-Pérez B, Cuypers LN, Moissonnier E, de Caluwé L, Müller J, Thielebein A, Tomazatos A, Jacobsen C, Pahlmann M, Becker-Ziaja B, Erameh C, Okogbenin S, Koundouno FR, Sidibé Y, Keïta K, Keita MB, Loi G, Kipela MFJM, Ki-Zerbo GA, Dia S, Lemey P, Günther S, Camara A, Soropogui B, Kafetzopoulou LE, Boumbaly S, Duraffour S.   +45 more
europepmc   +1 more source

Impact of COVID‐19 and Vaccination on Lower Urinary Tract Symptoms: Insights From a Prospective Cohort Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To evaluate the prevalence, clinical course, and risk factors of lower urinary tract symptoms (LUTS) in patients hospitalized with COVID‐19, and to assess associations with comorbidities, disease severity, and vaccination status. Methods We conducted a prospective cohort study of adult patients hospitalized with confirmed COVID‐19, who ...
Julia Duarte de Souza, Jose de Bessa Jr., Natássia Cristina Carboni Truzzi, Carolina Trigo Rocha, Bruno Camargo Rocha Paim de Araujo, Julyana Kanate Mazzoni Moromizato, Thulio Bosi Vieira Brandão, Rachel Mazoni Costa, Marcelo Hisano, Zein Mohamed Sammour, Homero Bruschini, William Carlos Nahas, Cristiano Mendes Gomes   +12 more
wiley   +1 more source