Results 271 to 280 of about 869,733 (343)

Animal Welfare as an Essential Element of One Health

Animal Research and One Health, EarlyView.
Philip Lymbery
wiley   +1 more source

Scale‐up of a monoclonal antibody CHO fed‐batch production in stirred tank bioreactors: Effect of hydrodynamic conditions and feeding regimen

Biotechnology Progress, EarlyView.
Abstract Key hydrodynamic‐related parameters such as volumetric power input (P/V), impeller configuration, aeration strategy, and maximum gas sparge rate, as well as an appropriate feeding strategy, must be carefully selected to improve production yields in bioreactor.
Lucas Lemire, Sebastian‐Juan Reyes, Yves Durocher, Robert Voyer, Olivier Henry, Phuong Lan Pham   +5 more
wiley   +1 more source

SYBR green one-step qRT-PCR for the detection of SARS-CoV-2 RNA in saliva

, 2020
Diep R Ganguly, Sarah Rottet, Susan H. Yee, Wei Yih Hee, AB Smith, N.W. Khin, Anthony A. Millar, Aude M. Fahrer   +7 more
openalex   +1 more source

Harnessing chimeric antigen receptor macrophages against solid tumors

Cancer Communications, EarlyView.
Abstract Macrophages are prevalent in multiple tumors and exhibit diverse and potent functional activities. Therapeutic reprogramming of macrophage phenotypes represents a promising strategy for cancer immunotherapy. Engineering chimeric antigen receptors (CARs) to endow macrophages with anti‐tumor capacities demonstrated encouraging efficacy ...
Mengru Wang, Zhen Qin, Xiu‐Wu Bian, Yu Shi   +3 more
wiley   +1 more source

Polysialosides Outperform Sulfated Analogs for Binding with SARS-CoV-2. [PDF]

Small
Khatri V, Boback N, Abdelwahab H, Niemeyer D, Palmer TM, Sahoo AK, Kerkhoff Y, Ludwig K, Heinze J, Balci D, Trimpert J, Haag R, Povolotsky TL, Netz RR, Drosten C, Lauster DC, Bhatia S.   +16 more
europepmc   +1 more source

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease‐Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

Chemistry &Biodiversity, EarlyView.
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida, Vitor de Souza Mazucato, Ludmilla Tonani, Marcia Regina von Zeska Kress, Gisele Barbosa, Renata Krogh, Adriano Defini Andricopulo, Leonardo Luiz Gomes Ferreira, Paulo Cezar Vieira   +8 more
wiley   +1 more source

Comparative analysis of neutralization assays performed using live SARS-CoV-2 virus and pseudovirus to assess immunogenicity of a bivalent SARS-CoV-2 protein vaccine in humans. [PDF]

Front Immunol
Gao C, Yi J, Baidoo A, Liu D, Li J, Li D, Li J, Zhou Q, Xie L.   +8 more
europepmc   +1 more source

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

Chemistry &Biodiversity, EarlyView.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade, Edson de O. Lima Filho, Caio F. Valadão, Luana da S. M. Forezi, Fernando de C. da Silva   +4 more
wiley   +1 more source

Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition

, 2020
Allison J. Greaney, Tyler N. Starr, Pavlo Gilchuk, Seth J. Zost, Elad Binshtein, Andrea N. Loes, Sarah K. Hilton, John Huddleston, Rachel Eguia, Katharine H. D. Crawford, Adam S. Dingens, Rachel S. Nargi, Rachel E. Sutton, Naveenchandra Suryadevara, Paul W. Rothlauf, Zhuoming Liu, Sean P. J. Whelan, Robert H. Carnahan, James E. Crowe, Jesse D. Bloom   +19 more
openalex   +1 more source

Incidence of and Risk Factors for SARS-CoV-2 Infection Among Vaccinated Healthcare Workers During Emergence of SARS-CoV-2 Gamma Variant in the Amazon Region, Brazil, 2021. [PDF]

Clin Infect Dis
Parra G, Lessa FC, Campelo E, Amorim Ramos TC, Vieira AR, Lalwani P, Nichiata LYI, Silva-Flannery L, Siza C, Lima KJV, Tapajos AC, Vieira A, Plucinski M, Marston BJ, Morgan J, Esteves RJF, Fernandes da Costa C, Naveca FG, Araujo G, Padoveze MC, Brazil Healthcare Personnel COVID-19 Team .   +20 more
europepmc   +1 more source