Results 351 to 360 of about 1,228,387 (374)

Determinants of susceptibility to SARS-CoV-2 infection in murine ACE2. [PDF]

J Virol
Kondo T, Suzuki R, Yajima H, Kawahara S, Yamaya K, Ichikawa T, Tsujino S, Suzuki S, Tamura T, Hashiguchi T, Fukuhara T.   +10 more
europepmc   +1 more source

Harnessing Viral Proteases for Cellular and Molecular Engineering

Chemistry–Methods, EarlyView.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui, Tien‐Hung Lan, Yubin Zhou   +2 more
wiley   +1 more source

Identification and targeting of regulators of SARS-CoV-2-host interactions in the airway epithelium. [PDF]

Sci Adv
Dirvin B, Noh H, Tomassoni L, Cao D, Zhou Y, Ke X, Qian J, Jangra S, Schotsaert M, García-Sastre A, Karan C, Califano A, Cardoso WV.   +12 more
europepmc   +1 more source

Continuous Flow Block Copolymer Nanoaggregate Synthesis and Their Flow Dialysis Purification

Chemistry–Methods, EarlyView.
This work details the methodology for the synthesis of block copolymer nanoparticles through continuous flow self‐assembly and purification via flow dialysis. Nanoaggregates are formed by mixing block copolymer solutions in THF with water, followed by dialysis to eliminate excess solvent.
Gayathri Dev Ammini, Lakshani J. Weerarathna, Tanja Junkers   +2 more
wiley   +1 more source

SARS-CoV-2 RNA-binding protein suppresses extracellular miRNA release. [PDF]

RNA Biol
Mun H, Shin CH, Fei Q, Giraldo AEL, Choi KM, Lee JW, Kim K, Min KW, Shi L, Bedford MT, Kim DC, Chun YL, Ryu S, Kim D, Chang JH, Westrope RT, Shay M, Nguyen E, Hur JK, Agyenda A, Kim NC, Kang SU, Lee W, Yoon JH.   +23 more
europepmc   +1 more source

A Scalable L‐α‐Glycerophosphorylcholine Synthesis through the Automatic pH‐Controlled (R)‐Glycidol Ring Opening with Phosphorylcholine

Chemistry–Methods, EarlyView.
Automatic titrator enables the regioselective ring opening of (R)‐glycidol in water in the presence of phosphorylcholine, leading to the synthesis of L‐α‐glycerophosphorylcholine, a commercially available drug, in very high yield. The reaction is triggered by a minimum amount of NaOH and reactants, while the optimal pH is precisely regulated through ...
Antonio Massa, Mauro Anibaldi, Lorenzo De Ferra   +2 more
wiley   +1 more source

SARS-CoV-2 Infection and Childhood Islet Autoimmunity.

JAMA Pediatr
Walker GJ, Mallitt KA, Craig ME, Ashwood P, Barry SC, Brown JD, Caguicla J, Davis EA, Hamilton-Williams EE, Harrison LC, Haynes A, Huynh T, Martin G, McGorm KJ, Morahan G, Naing Z, Oakey H, Penno MAS, Sevendal A, Sinnott RO, Soldatos G, Thomson RL, Tye-Din J, Vuillermin PJ, Ward EJ, Wentworth JM, Colman PG, Couper JJ, Kim KW, Rawlinson WD, ENDIA Study Group.   +30 more
europepmc   +1 more source

Structural impact of synonymous mutations in six SARS-CoV-2 Variants of Concern. [PDF]

PLoS One
Ziesel A, Jabbari H.
europepmc   +1 more source

Hierarchical clustering of clinical and flow cytometry parameters is associated with deterioration in patients with community‐acquired pneumonia in the emergency department: A preliminary study

Cytometry Part B: Clinical Cytometry, EarlyView.
ABSTRACT Anticipating the evolution of septic patients with community‐acquired pneumonia (CAP) is challenging for front‐line physicians in the Emergency Department (ED). Prognosis depends mainly on early identification, antibiotics, organ support, but also immune status.
Thomas Lafon, Robin Jeannet, Thomas Daix, Guillaume Monneret, Jean Feuillard   +4 more
wiley   +1 more source